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ClinicalTrials.gov 9 recruiting now early-phase tilt small index

Adenoid Cystic Carcinoma: early-phase trial registry

9 of 17 indexed Adenoid Cystic Carcinoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,004 of 28,707 conditions by registered trial count.

17 US clinical trials · 9 currently recruiting · #1,004 of 28,707 conditions by registered trial count

Adenoid Cystic Carcinoma: 17 US clinical trials tracked, 9 recruiting.

Adenoid Cystic Carcinoma is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 16 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 5 of these trials.

Enrollment posture brief

Registry condition adenoid-cystic-carcinoma

OPEN 9 | RECR 53% | LATE 0 | EARLY 16 | RANK #1004 | SPON 5

Nearest open-share peer: Advanced Hepatocellular Carcinoma (53% recruiting · 17 trials)

Acute Myeloid Leukemia, in R70.6%Adenoid Cystic Carcinoma (th…53%Abdominal Aortic Aneurysm52.9%Acute Lymphoblastic Leukemia23.5%Actinic Keratosis11.8%
Open-enrollment share among volume-matched conditions near Adenoid Cystic Carcinoma

Adenoid Cystic Carcinoma lists 9 open slots (53% of 17 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Adenoid Cystic Carcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Adenoid Cystic Carcinoma is recruiting above its size-band peers.

    9 of 17 indexed trials (52.9%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Adenoid Cystic Carcinoma research.

    Memorial Sloan Kettering Cancer Center accounts for 5 of 17 trials (29.4%). 11 distinct sponsors appear on at least one study for this condition label.

  3. Most Adenoid Cystic Carcinoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 38 among the 17 trials that report a genuine target (sentinel values excluded). 12 of those (70.6%) plan for fewer than 100 participants.

  4. Adenoid Cystic Carcinoma research is mostly interventional.

    17 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 29

Open and recent trials

17 total, page 1 of 1

RECRUITING Phase 1 319 participants

A Study of XMT-1660 in Participants With Solid Tumors

Mersana Therapeutics

NCT05377996

RECRUITING Phase 1 242 participants

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

VM Oncology

NCT03556228

RECRUITING Phase 1 105 participants

Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)

Rgenta Therapeutics

NCT06462183

RECRUITING Phase 1 100 participants

Study of REM-422 in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma

Remix Therapeutics

NCT06118086

RECRUITING Phase 1 67 participants

A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit

Novelty Nobility

NCT06805825

RECRUITING Phase 2 35 participants

A Phase 2 Trial of Ivonescimab for Patients With Advanced, Metastatic Salivary Gland Cancers

Glenn J. Hanna

NCT06805617

RECRUITING Phase 2 34 participants

A Study of Enfortumab Vedotin in People With Adenoid Cystic Carcinoma

Memorial Sloan Kettering Cancer Center

NCT06891560

RECRUITING Phase 1 32 participants

CB-103 With Either Lenvatinib or Abemaciclib in Patients With NOTCH ACC

Glenn J. Hanna

NCT05774899

RECRUITING NA 32 participants

Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: The SOLAR Trial

Dana-Farber Cancer Institute

NCT04883671

ACTIVE NOT RECRUITING Phase 2 818 participants

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

National Cancer Institute (NCI)

NCT02834013

ACTIVE NOT RECRUITING Phase 2 64 participants

Lenvatinib and Pembrolizumab in People With Advanced Adenoid Cystic Carcinoma and Other Salivary Gland Cancers

Memorial Sloan Kettering Cancer Center

NCT04209660

ACTIVE NOT RECRUITING Phase 2 45 participants

MC200708 Pemetrexed and Pembrolizumab for the Treatment of Recurrent and/or Metastatic Salivary Gland Cancer

Mayo Clinic

NCT04895735

ACTIVE NOT RECRUITING Phase 2 35 participants

9-ING-41 Plus Carboplatin in Salivary Gland Carcinoma

Glenn J. Hanna

NCT05010629

ACTIVE NOT RECRUITING Phase 2 33 participants

Testing Lenvatinib in Patients With Adenoid Cystic Carcinoma

Memorial Sloan Kettering Cancer Center

NCT02780310

ACTIVE NOT RECRUITING Phase 1 14 participants

AL101 Before Surgery for the Treatment of Notch Activated Adenoid Cystic Cancer

M.D. Anderson Cancer Center

NCT04973683

COMPLETED Phase 2 38 participants

Regorafenib in Patients With Progressive, Recurrent/Metastatic Adenoid Cystic Carcinoma

Memorial Sloan Kettering Cancer Center

NCT02098538

COMPLETED Phase 2 33 participants

Axitinib (AG-013736) in Patients With Progressive, Recurrent/Metastatic Adenoid Cystic Carcinoma

Memorial Sloan Kettering Cancer Center

NCT01558661

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 9

Named interventions

Most-linked intervention names on Adenoid Cystic Carcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Lenvatinib Drug
3 trials
Computed Tomography Procedure
2 trials
Biospecimen Collection Procedure
2 trials
AG-013736 (axitinib) Drug
1 trials
AL101 Drug
1 trials
Pemetrexed Disodium Drug
1 trials
XMT-1660 Drug
1 trials
9-ING-41 Drug
1 trials

US sites by state

Facility locations filed on Adenoid Cystic Carcinoma trials. A trial with sites in several states counts in each.

New York 9 trials
Massachusetts 7 trials
Texas 6 trials
New Jersey 5 trials
Michigan 4 trials
California 4 trials
Florida 3 trials
Arizona 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Adenoid Cystic Carcinoma page

17 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Adenoid Cystic Carcinoma condition card totals 17 registered trials; most-linked intervention Lenvatinib; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.