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2026 data Public-data reference. official source

Adenoid Cystic Carcinoma

Open-data reference.

17 US clinical trials · 9 currently recruiting

Active & Recent Trials

RECRUITING Phase 1 319 participants

A Study of XMT-1660 in Participants With Solid Tumors

Mersana Therapeutics

NCT05377996

RECRUITING Phase 1 242 participants

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

VM Oncology

NCT03556228

RECRUITING Phase 1 105 participants

Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)

Rgenta Therapeutics

NCT06462183

RECRUITING Phase 1 100 participants

Study of REM-422 in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma

Remix Therapeutics

NCT06118086

RECRUITING Phase 1 67 participants

A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit

Novelty Nobility

NCT06805825

RECRUITING Phase 2 35 participants

A Phase 2 Trial of Ivonescimab for Patients With Advanced, Metastatic Salivary Gland Cancers

Glenn J. Hanna

NCT06805617

RECRUITING Phase 2 34 participants

A Study of Enfortumab Vedotin in People With Adenoid Cystic Carcinoma

Memorial Sloan Kettering Cancer Center

NCT06891560

RECRUITING Phase 1 32 participants

CB-103 With Either Lenvatinib or Abemaciclib in Patients With NOTCH ACC

Glenn J. Hanna

NCT05774899

RECRUITING NA 32 participants

Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: The SOLAR Trial

Dana-Farber Cancer Institute

NCT04883671

ACTIVE NOT RECRUITING Phase 2 818 participants

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

National Cancer Institute (NCI)

NCT02834013

ACTIVE NOT RECRUITING Phase 2 64 participants

Lenvatinib and Pembrolizumab in People With Advanced Adenoid Cystic Carcinoma and Other Salivary Gland Cancers

Memorial Sloan Kettering Cancer Center

NCT04209660

ACTIVE NOT RECRUITING Phase 2 45 participants

MC200708 Pemetrexed and Pembrolizumab for the Treatment of Recurrent and/or Metastatic Salivary Gland Cancer

Mayo Clinic

NCT04895735

ACTIVE NOT RECRUITING Phase 2 35 participants

9-ING-41 Plus Carboplatin in Salivary Gland Carcinoma

Glenn J. Hanna

NCT05010629

ACTIVE NOT RECRUITING Phase 2 33 participants

Testing Lenvatinib in Patients With Adenoid Cystic Carcinoma

Memorial Sloan Kettering Cancer Center

NCT02780310

ACTIVE NOT RECRUITING Phase 1 14 participants

AL101 Before Surgery for the Treatment of Notch Activated Adenoid Cystic Cancer

M.D. Anderson Cancer Center

NCT04973683

COMPLETED Phase 2 38 participants

Regorafenib in Patients With Progressive, Recurrent/Metastatic Adenoid Cystic Carcinoma

Memorial Sloan Kettering Cancer Center

NCT02098538

COMPLETED Phase 2 33 participants

Axitinib (AG-013736) in Patients With Progressive, Recurrent/Metastatic Adenoid Cystic Carcinoma

Memorial Sloan Kettering Cancer Center

NCT01558661

Phase Distribution

PhaseTrial count
Early Phase 1 7
Phase 2 9

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Adenoid Cystic Carcinoma Trial Landscape

ClinicalTrials.gov lists 17 US studies indexed under Adenoid Cystic Carcinoma, and 9 of those are currently open to recruitment — roughly 53% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Adenoid Cystic Carcinoma shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 16 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Adenoid Cystic Carcinoma is led by Memorial Sloan Kettering Cancer Center with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 17 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Adenoid Cystic Carcinoma?

PlainTrial tracks 17 US clinical trials for Adenoid Cystic Carcinoma, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Adenoid Cystic Carcinoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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