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ClinicalTrials.gov 11 recruiting now early-phase tilt

Smoking, Cigarette: early-phase trial registry

11 of 22 indexed Smoking, Cigarette trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #756 of 28,707 conditions by registered trial count.

22 US clinical trials · 11 currently recruiting · #756 of 28,707 conditions by registered trial count

Smoking, Cigarette: 22 US clinical trials tracked, 11 recruiting.

Smoking, Cigarette is the subject of 22 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Medical University of South Carolina, running 2 of these trials.

Enrollment posture brief

Registry condition smoking-cigarette

OPEN 11 | RECR 50% | LATE 0 | EARLY 4 | RANK #756 | SPON 2

Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)

Advanced Melanoma63.6%Smoking, Cigarette (this)50%Acute Myeloid Leukemia Arisi18.2%Adenocarcinoma of the Prosta0%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Smoking, Cigarette

Smoking, Cigarette lists 11 open slots (50% of 22 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Smoking, Cigarette on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Smoking, Cigarette is recruiting above its size-band peers.

    11 of 22 indexed trials (50%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Smoking, Cigarette trials is spread across many organizations.

    Medical University of South Carolina accounts for 2 of 22 trials (9.1%). 18 distinct sponsors appear on at least one study for this condition label.

  3. Typical Smoking, Cigarette enrolment sits around 100 participants.

    Median target enrolment is 100 among the 22 trials that report a genuine target (sentinel values excluded). 11 of those (50%) plan for fewer than 100 participants.

  4. Smoking, Cigarette research is mostly interventional.

    18 interventional and 4 observational studies make up this index (81.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 21

Open and recent trials

22 total, page 1 of 1

RECRUITING 5,122 participants

The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study

Memorial Sloan Kettering Cancer Center

NCT06535867

RECRUITING NA 900 participants

Dyadic Financial Incentive Treatments for Dual Smoker Couples

University of Georgia

NCT06296849

RECRUITING NA 768 participants

Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

University of Virginia

NCT05660525

RECRUITING NA 231 participants

Optimizing Tobacco Treatment Delivery for People Living With HIV

Medical University of South Carolina

NCT05019495

RECRUITING 200 participants

University of Michigan COPD Identification Through Lung Cancer Screening Cohort Study - MAP2

University of Michigan

NCT07482475

RECRUITING Phase 1 100 participants

Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation

University of Pennsylvania

NCT03721822

RECRUITING 100 participants

Vape Use Among Younger & Older Smokers

Abramson Cancer Center at Penn Medicine

NCT07214168

RECRUITING NA 50 participants

ACT Lung Health Intervention: Phase Two

Dana-Farber Cancer Institute

NCT06945120

RECRUITING NA 48 participants

Maternal Smoking Cessation and Pediatric Obesity Prevention

State University of New York at Buffalo

NCT03514602

RECRUITING NA 20 participants

Trauma-Informed Care for Smoking Cessation for Pregnancy

University of California, San Francisco

NCT07129590

RECRUITING NA 10 participants

A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home

Memorial Sloan Kettering Cancer Center

NCT06693700

ACTIVE NOT RECRUITING Phase 1 47 participants

Biomarkers of Exposure and Effect in Standardized Research E-cigarette (SREC) Users

Masonic Cancer Center, University of Minnesota

NCT04003805

COMPLETED NA 1,944 participants

Helping Poor Smokers Quit

Washington University School of Medicine

NCT03194958

COMPLETED NA 663 participants

Tobacco/Nicotine Purchase Patterns Across SES

Virginia Polytechnic Institute and State University

NCT06795997

COMPLETED NA 433 participants

The Impact of Standardized Tobacco Product Packaging on Young Adults in the Retail Environment

RAND

NCT05973981

COMPLETED NA 165 participants

A Facebook Intervention for Young Sexual and Gender Minority Smokers

University of California, San Francisco

NCT03259360

COMPLETED Early Phase 1 99 participants

Hollings Cancer Center Varenicline Sampling Study

Medical University of South Carolina

NCT03742154

COMPLETED NA 95 participants

Personalized Feedback for Smokers With Elevated Anxiety Sensitivity

University of Houston

NCT03382093

COMPLETED NA 70 participants

FDA Cigarette Warning Labels: Eye Tracking Study

Abramson Cancer Center at Penn Medicine

NCT04936724

COMPLETED NA 61 participants

Connecting Alaska Native People to Quit Smoking

Mayo Clinic

NCT03645941

COMPLETED Phase 2 58 participants

AXS-05 Phase II Trial on Smoking Behavior

James Davis

NCT03471767

COMPLETED 30 participants

A Comparison of Exhaled Carbon Monoxide Measurements Using the iCOquit Smokerlyzer and Vitalograph Breath CO Monitor vs Carboxyhemoglobin From Venous Samples While Validating a Mobile Research Application

Rose Research Center

NCT04826549

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 1

Named interventions

Most-linked intervention names on Smoking, Cigarette records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Pictorial Warning Labels Other
1 trials
Smoking Information Control Behavioral
1 trials
Personalized Feedback Intervention Behavioral
1 trials
Basic Needs Navigator Behavioral
1 trials
Specialized Quitline Behavioral
1 trials
Tax Conditions Behavioral
1 trials
Varenicline 0.5 MG Drug
1 trials
Bupropion SR Drug
1 trials

US sites by state

Facility locations filed on Smoking, Cigarette trials. A trial with sites in several states counts in each.

Pennsylvania 4 trials
New York 3 trials
Virginia 2 trials
South Carolina 2 trials
North Carolina 2 trials
Minnesota 2 trials
California 2 trials
Texas 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Smoking, Cigarette page

22 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Smoking, Cigarette condition card totals 22 registered trials; most-linked intervention Pictorial Warning Labels; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.