Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 7 recruiting now early-phase tilt

Recurrent Prostate Cancer: early-phase trial registry

7 of 22 indexed Recurrent Prostate Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #756 of 28,707 conditions by registered trial count.

22 US clinical trials · 7 currently recruiting · #756 of 28,707 conditions by registered trial count

Recurrent Prostate Cancer: 22 US clinical trials tracked, 7 recruiting.

Recurrent Prostate Cancer is the subject of 22 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 7 of these trials.

Enrollment posture brief

Registry condition recurrent-prostate-cancer

OPEN 7 | RECR 32% | LATE 1 | EARLY 18 | RANK #756 | SPON 7

Nearest open-share peer: Childhood Obesity (32% recruiting · 44 trials)

Advanced Melanoma63.6%Recurrent Prostate Cance (th…32%Acute Myeloid Leukemia Arisi18.2%Adenocarcinoma of the Prosta0%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Recurrent Prostate Cancer

Recurrent Prostate Cancer lists 7 open slots (32% of 22 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Recurrent Prostate Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Recurrent Prostate Cancer is recruiting below its size-band peers.

    7 of 22 indexed trials (31.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Recurrent Prostate Cancer research.

    National Cancer Institute (NCI) accounts for 7 of 22 trials (31.8%). 15 distinct sponsors appear on at least one study for this condition label.

  3. Most Recurrent Prostate Cancer trials plan to enrol fewer than 100 people.

    Median target enrolment is 49 among the 22 trials that report a genuine target (sentinel values excluded). 17 of those (77.3%) plan for fewer than 100 participants.

  4. Recurrent Prostate Cancer research is mostly interventional.

    21 interventional and 1 observational studies make up this index (95.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 28Phase 31

Open and recent trials

22 total, page 1 of 1

RECRUITING Phase 2 532 participants

Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial

Mayo Clinic

NCT06378866

RECRUITING Phase 2 464 participants

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

VA Office of Research and Development

NCT04787744

RECRUITING Phase 1 66 participants

Clinical Study to Assess the Safety and Efficacy of the SpectraCure P18 System

SpectraCure AB

NCT03067051

RECRUITING Phase 2 65 participants

Enzalutamide and PDS01ADC in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering Therapy

National Cancer Institute (NCI)

NCT06096870

RECRUITING Phase 2 60 participants

PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher Test Scores

H. Lee Moffitt Cancer Center and Research Institute

NCT03495427

RECRUITING 16 participants

Tumor Microenvironment Analysis of Prostate Cancer Metastasis

Columbia University

NCT05304858

RECRUITING Phase 1 14 participants

Trial of pTVG-HP+Nivo+Targeted Ablation of Resistant Lesions in Non-Castrate RecurrentOMPC

University of Wisconsin, Madison

NCT07090148

ACTIVE NOT RECRUITING NA 130 participants

Controlled Low Calorie Diet in Reducing Side Effects and Increasing Response to Chemotherapy in Patients With Breast or Prostate Cancer

University of Southern California

NCT01802346

ACTIVE NOT RECRUITING Phase 1 42 participants

High-Dose Rate Brachytherapy and Stereotactic Body Radiation Therapy in Treating Patients With Prostate Cancer

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

NCT01655836

ACTIVE NOT RECRUITING Phase 1 26 participants

Stereotactic Body Radiation Therapy in Treating Patients With Prostate Cancer After Undergoing Surgery

City of Hope Medical Center

NCT01923506

ACTIVE NOT RECRUITING Phase 1 25 participants

Enzalutamide, Radiation Therapy and Hormone Therapy in Treating Patients With Intermediate or High-Risk Prostate Cancer

Thomas Jefferson University

NCT02023463

ACTIVE NOT RECRUITING Phase 1 8 participants

Study of ADXS-504 Immunotherapy for Recurrent Prostate Cancer

Mark Stein

NCT05077098

COMPLETED Phase 3 1,050 participants

Docetaxel and Prednisone With or Without Bevacizumab in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy

National Cancer Institute (NCI)

NCT00110214

COMPLETED Phase 1 100 participants

Treating Patients With Metastatic Prostate Cancer Not Responding to Hormone and Chemotherapy

National Cancer Institute (NCI)

NCT00331344

COMPLETED Phase 1 88 participants

Enzalutamide and Mifepristone in Treating Patients With Metastatic Hormone Resistant Prostate Cancer

University of Chicago

NCT02012296

COMPLETED Phase 1 80 participants

Combination Chemotherapy in Treating Patients With Metastatic or Unresectable Solid Tumors

National Cancer Institute (NCI)

NCT00058253

COMPLETED Phase 2 49 participants

Lapatinib Ditosylate in Treating Patients With a Rising PSA Indicating Recurrent Prostate Cancer

National Cancer Institute (NCI)

NCT00103194

COMPLETED NA 32 participants

Soy Isoflavones in Treating Patients With Recurrent Prostate Cancer or Rising Prostate-Specific Antigen

Ohio State University Comprehensive Cancer Center

NCT01682941

COMPLETED Phase 2 19 participants

Magnetic Resonance Imaging in Measuring the Effect of Cabozantinib in Patients With Castrate Resistant Prostate Cancer

University of Chicago

NCT01599793

COMPLETED Phase 2 17 participants

17-AAG in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Previous Hormone Therapy

National Cancer Institute (NCI)

NCT00118092

COMPLETED Phase 2 17 participants

Linsitinib in Treating Patients With Asymptomatic or Mildly Symptomatic Metastatic Prostate Cancer

National Cancer Institute (NCI)

NCT01533246

COMPLETED Phase 1 15 participants

Sodium Selenite and Radiation Therapy in Treating Patients With Metastatic Cancer

Stanford University

NCT02184533

Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 8
Phase 3 1

Named interventions

Most-linked intervention names on Recurrent Prostate Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

laboratory biomarker analysis Other
9 trials
tanespimycin Drug
2 trials
pharmacological study Other
2 trials
docetaxel Drug
2 trials
Enzalutamide Drug
2 trials
prednisone Drug
2 trials
mitoxantrone hydrochloride Drug
1 trials
mifepristone Drug
1 trials

US sites by state

Facility locations filed on Recurrent Prostate Cancer trials. A trial with sites in several states counts in each.

New York 5 trials
California 5 trials
Pennsylvania 4 trials
Minnesota 4 trials
Illinois 4 trials
Wisconsin 3 trials
Ohio 3 trials
Florida 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Recurrent Prostate Cancer page

22 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Recurrent Prostate Cancer condition card totals 22 registered trials; most-linked intervention laboratory biomarker analysis; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.