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2026 data Public-data reference. official source

Recurrent Prostate Cancer

Open-data reference.

22 US clinical trials · 7 currently recruiting

Active & Recent Trials

RECRUITING Phase 2 532 participants

Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial

Mayo Clinic

NCT06378866

RECRUITING Phase 2 464 participants

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

VA Office of Research and Development

NCT04787744

RECRUITING Phase 1 66 participants

Clinical Study to Assess the Safety and Efficacy of the SpectraCure P18 System

SpectraCure AB

NCT03067051

RECRUITING Phase 2 65 participants

Enzalutamide and PDS01ADC in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering Therapy

National Cancer Institute (NCI)

NCT06096870

RECRUITING Phase 2 60 participants

PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher Test Scores

H. Lee Moffitt Cancer Center and Research Institute

NCT03495427

RECRUITING 16 participants

Tumor Microenvironment Analysis of Prostate Cancer Metastasis

Columbia University

NCT05304858

RECRUITING Phase 1 14 participants

Trial of pTVG-HP+Nivo+Targeted Ablation of Resistant Lesions in Non-Castrate RecurrentOMPC

University of Wisconsin, Madison

NCT07090148

ACTIVE NOT RECRUITING NA 130 participants

Controlled Low Calorie Diet in Reducing Side Effects and Increasing Response to Chemotherapy in Patients With Breast or Prostate Cancer

University of Southern California

NCT01802346

ACTIVE NOT RECRUITING Phase 1 42 participants

High-Dose Rate Brachytherapy and Stereotactic Body Radiation Therapy in Treating Patients With Prostate Cancer

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

NCT01655836

ACTIVE NOT RECRUITING Phase 1 26 participants

Stereotactic Body Radiation Therapy in Treating Patients With Prostate Cancer After Undergoing Surgery

City of Hope Medical Center

NCT01923506

ACTIVE NOT RECRUITING Phase 1 25 participants

Enzalutamide, Radiation Therapy and Hormone Therapy in Treating Patients With Intermediate or High-Risk Prostate Cancer

Thomas Jefferson University

NCT02023463

ACTIVE NOT RECRUITING Phase 1 8 participants

Study of ADXS-504 Immunotherapy for Recurrent Prostate Cancer

Mark Stein

NCT05077098

COMPLETED Phase 3 1,050 participants

Docetaxel and Prednisone With or Without Bevacizumab in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy

National Cancer Institute (NCI)

NCT00110214

COMPLETED Phase 1 100 participants

Treating Patients With Metastatic Prostate Cancer Not Responding to Hormone and Chemotherapy

National Cancer Institute (NCI)

NCT00331344

COMPLETED Phase 1 88 participants

Enzalutamide and Mifepristone in Treating Patients With Metastatic Hormone Resistant Prostate Cancer

University of Chicago

NCT02012296

COMPLETED Phase 1 80 participants

Combination Chemotherapy in Treating Patients With Metastatic or Unresectable Solid Tumors

National Cancer Institute (NCI)

NCT00058253

COMPLETED Phase 2 49 participants

Lapatinib Ditosylate in Treating Patients With a Rising PSA Indicating Recurrent Prostate Cancer

National Cancer Institute (NCI)

NCT00103194

COMPLETED NA 32 participants

Soy Isoflavones in Treating Patients With Recurrent Prostate Cancer or Rising Prostate-Specific Antigen

Ohio State University Comprehensive Cancer Center

NCT01682941

COMPLETED Phase 2 19 participants

Magnetic Resonance Imaging in Measuring the Effect of Cabozantinib in Patients With Castrate Resistant Prostate Cancer

University of Chicago

NCT01599793

COMPLETED Phase 2 17 participants

17-AAG in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Previous Hormone Therapy

National Cancer Institute (NCI)

NCT00118092

COMPLETED Phase 2 17 participants

Linsitinib in Treating Patients With Asymptomatic or Mildly Symptomatic Metastatic Prostate Cancer

National Cancer Institute (NCI)

NCT01533246

COMPLETED Phase 1 15 participants

Sodium Selenite and Radiation Therapy in Treating Patients With Metastatic Cancer

Stanford University

NCT02184533

Phase Distribution

PhaseTrial count
Early Phase 1 10
Phase 2 8
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Recurrent Prostate Cancer Trial Landscape

ClinicalTrials.gov lists 22 US studies indexed under Recurrent Prostate Cancer, and 7 of those are currently open to recruitment — roughly 32% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Recurrent Prostate Cancer shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 18 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Recurrent Prostate Cancer is led by National Cancer Institute (NCI) with 7 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 22 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Recurrent Prostate Cancer?

PlainTrial tracks 22 US clinical trials for Recurrent Prostate Cancer, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Recurrent Prostate Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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