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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Recurrent B-Cell Non-Hodgkin Lymphoma: early-phase trial registry

5 of 13 indexed Recurrent B-Cell Non-Hodgkin Lymphoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 5 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Recurrent B-Cell Non-Hodgkin Lymphoma: 13 US clinical trials tracked, 5 recruiting.

Recurrent B-Cell Non-Hodgkin Lymphoma is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 3 of these trials.

Enrollment posture brief

Registry condition recurrent-b-cell-non-hodgkin-lymphoma

OPEN 5 | RECR 38% | LATE 0 | EARLY 13 | RANK #1315 | SPON 3

Nearest open-share peer: Anaplastic Oligodendroglioma (38% recruiting · 13 trials)

ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Recurrent B-Cell Non-Hod (th…38%Accidental Falls30.8%Actinic Keratoses23.1%
Open-enrollment share among volume-matched conditions near Recurrent B-Cell Non-Hodgkin Lymphoma

Recurrent B-Cell Non-Hodgkin Lymphoma lists 5 open slots (38% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Recurrent B-Cell Non-Hodgkin Lymphoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Recurrent B-Cell Non-Hodgkin Lymphoma is recruiting below its size-band peers.

    5 of 13 indexed trials (38.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Recurrent B-Cell Non-Hodgkin Lymphoma research.

    National Cancer Institute (NCI) accounts for 3 of 13 trials (23.1%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Most Recurrent B-Cell Non-Hodgkin Lymphoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 30 among the 13 trials that report a genuine target (sentinel values excluded). 13 of those (100%) plan for fewer than 100 participants.

  4. Recurrent B-Cell Non-Hodgkin Lymphoma research is mostly interventional.

    13 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 23

Open and recent trials

13 total, page 1 of 1

RECRUITING Phase 2 40 participants

Loncastuximab Tesirine for the Treatment of Relapsed or Refractory B-Cell Malignancies

University of Washington

NCT05453396

RECRUITING Phase 1 32 participants

Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell Lymphoma

National Cancer Institute (NCI)

NCT05272384

RECRUITING Phase 1 25 participants

CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies

Mayo Clinic

NCT04892277

RECRUITING Phase 1 15 participants

Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) Following Stem Cell Transplantation for the Treatment of Intermediate or High Grade B-cell Non-Hodgkin Lymphoma

City of Hope Medical Center

NCT05432635

RECRUITING Phase 1 15 participants

Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) for the Treatment of Intermediate or High Grade B-Cell Non-Hodgkin Lymphoma

City of Hope Medical Center

NCT05801913

ACTIVE NOT RECRUITING Phase 1 53 participants

A Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Express a CD20-Specific Chimeric Antigen Receptor for Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas

Fred Hutchinson Cancer Center

NCT03277729

ACTIVE NOT RECRUITING Phase 1 48 participants

Testing the Safety of the Anti-cancer Drugs Tazemetostat and Belinostat in Patients With Lymphomas That Have Resisted Treatment

National Cancer Institute (NCI)

NCT05627245

ACTIVE NOT RECRUITING Phase 1 43 participants

Selinexor Plus Combination Chemotherapy in Treating Patients With Advanced B Cell Non-Hodgkin Lymphoma

Barbara Ann Karmanos Cancer Institute

NCT03147885

ACTIVE NOT RECRUITING Phase 2 34 participants

Epcoritamab and Lenalidomide in Treating Patients With Refractory or Relapsed Immunodeficiency-Related Large B-Cell Lymphoma

Northwestern University

NCT06723457

ACTIVE NOT RECRUITING Phase 1 30 participants

R-ICE and Lenalidomide in Treating Patients With First-Relapse/Primary Refractory Diffuse Large B-Cell Lymphoma

Academic and Community Cancer Research United

NCT02628405

ACTIVE NOT RECRUITING Phase 1 24 participants

Alisertib, Bortezomib, and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or B-cell Low Grade Non-Hodgkin Lymphoma

National Cancer Institute (NCI)

NCT01695941

ACTIVE NOT RECRUITING Phase 2 10 participants

TTI-622 in Combination With Pembrolizumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Mayo Clinic

NCT05507541

ACTIVE NOT RECRUITING Phase 1 4 participants

An Early Phase Study of Venetoclax, Lenalidomide, and Rituximab/Hyaluronidase in Slow-Growing Lymphomas That Have Come Back After Treatment or Have Not Responded to Treatment

Thomas Jefferson University

NCT04447716

Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 3

Named interventions

Most-linked intervention names on Recurrent B-Cell Non-Hodgkin Lymphoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Biospecimen Collection Procedure
6 trials
Computed Tomography Procedure
5 trials
Lenalidomide Drug
3 trials
Laboratory Biomarker Analysis Other
3 trials
Anti-CD19-CAR CMV-specific T-lymphocytes Biological
2 trials
Leukapheresis Procedure
2 trials
Rituximab Biological
2 trials
Positron Emission Tomography Procedure
2 trials

US sites by state

Facility locations filed on Recurrent B-Cell Non-Hodgkin Lymphoma trials. A trial with sites in several states counts in each.

New York 4 trials
California 4 trials
Minnesota 3 trials
Illinois 3 trials
Washington 2 trials
Pennsylvania 2 trials
New Jersey 2 trials
Iowa 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Recurrent B-Cell Non-Hodgkin Lymphoma page

13 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Recurrent B-Cell Non-Hodgkin Lymphoma condition card totals 13 registered trials; most-linked intervention Biospecimen Collection; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.