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ClinicalTrials.gov 3 recruiting now early-phase tilt

Recurrent Adult Acute Myeloid Leukemia: early-phase trial registry

3 of 20 indexed Recurrent Adult Acute Myeloid Leukemia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #848 of 28,707 conditions by registered trial count.

20 US clinical trials · 3 currently recruiting · #848 of 28,707 conditions by registered trial count

Recurrent Adult Acute Myeloid Leukemia: 20 US clinical trials tracked, 3 recruiting.

Recurrent Adult Acute Myeloid Leukemia is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 19 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 4 of these trials.

Enrollment posture brief

Registry condition recurrent-adult-acute-myeloid-leukemia

OPEN 3 | RECR 15% | LATE 0 | EARLY 19 | RANK #848 | SPON 4

Nearest open-share peer: Coronary Heart Disease (15% recruiting · 20 trials)

Advanced or Metastatic Solid55%ALS50%Abdominal Pain25%Acute Myocardial Infarction25%Recurrent Adult Acute My (th…15%
Open-enrollment share among volume-matched conditions near Recurrent Adult Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia lists 3 open slots (15% of 20 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Recurrent Adult Acute Myeloid Leukemia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Recurrent Adult Acute Myeloid Leukemia is recruiting below its size-band peers.

    3 of 20 indexed trials (15%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Recurrent Adult Acute Myeloid Leukemia research.

    National Cancer Institute (NCI) accounts for 4 of 20 trials (20%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Most Recurrent Adult Acute Myeloid Leukemia trials plan to enrol fewer than 100 people.

    Median target enrolment is 33 among the 20 trials that report a genuine target (sentinel values excluded). 16 of those (80%) plan for fewer than 100 participants.

  4. Recurrent Adult Acute Myeloid Leukemia research is mostly interventional.

    19 interventional and 1 observational studies make up this index (95% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 115Phase 24

Open and recent trials

20 total, page 1 of 1

RECRUITING Phase 1 127 participants

A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma

Mayo Clinic

NCT03017820

RECRUITING Phase 1 30 participants

Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

University of Chicago

NCT02333162

RECRUITING Phase 1 27 participants

CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid Leukemia

City of Hope Medical Center

NCT05672147

ACTIVE NOT RECRUITING Phase 1 135 participants

Vorinostat and Azacitidine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia

National Cancer Institute (NCI)

NCT00392353

ACTIVE NOT RECRUITING Phase 2 108 participants

Total Marrow and Lymphoid Irradiation and Chemotherapy Before DSCT in Treating Patients With High-Risk ALL or AML

City of Hope Medical Center

NCT02094794

ACTIVE NOT RECRUITING Phase 1 44 participants

Nintedanib and Azacitidine in Treating Participants With HOX Gene Overexpression Relapsed or Refractory Acute Myeloid Leukemia

Northwestern University

NCT03513484

ACTIVE NOT RECRUITING Phase 1 33 participants

A Phase I/II Trial of the MUC1 Inhibitor, GO-203-2C in Patients With Relapsed or Refractory Acute Myeloid Leukemia

Beth Israel Deaconess Medical Center

NCT02204085

ACTIVE NOT RECRUITING Phase 1 31 participants

Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm

City of Hope Medical Center

NCT02159495

ACTIVE NOT RECRUITING Phase 1 15 participants

Bortezomib, Sorafenib Tosylate, and Decitabine in Treating Patients With Acute Myeloid Leukemia

National Cancer Institute (NCI)

NCT01861314

COMPLETED Phase 1 199 participants

Filgrastim, Cladribine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Newly Diagnosed or Relapsed/Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Fred Hutchinson Cancer Center

NCT02044796

COMPLETED Phase 1 51 participants

GTI-2040 and High-Dose Cytarabine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia

National Cancer Institute (NCI)

NCT00070551

COMPLETED Phase 1 48 participants

CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Granulocytic Sarcoma

Wake Forest University Health Sciences

NCT02484391

COMPLETED Phase 2 43 participants

Azacitidine in Treating Patients With Relapsed Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia Who Have Undergone Stem Cell Transplant

Fred Hutchinson Cancer Center

NCT01083706

COMPLETED Phase 2 39 participants

Biomarkers in Predicting Treatment Response to Sirolimus and Chemotherapy in Patients With High-Risk Acute Myeloid Leukemia

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

NCT02583893

COMPLETED Phase 1 30 participants

Donor Natural Killer Cells in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

M.D. Anderson Cancer Center

NCT01787474

COMPLETED Phase 1 28 participants

Decitabine With GCLAM for Adults With Newly Diagnosed, Relapsed, or Refractory AML or High-Risk MDS

Fred Hutchinson Cancer Center

NCT02921061

COMPLETED 14 participants

Metabolic Changes in Blood Samples From Patients With Acute Myeloid Leukemia

Wake Forest University Health Sciences

NCT02581917

COMPLETED Phase 1 13 participants

Pacritinib and Chemotherapy in Treating Patients With Acute Myeloid Leukemia and FLT3 Mutations

Bhavana Bhatnagar

NCT02323607

COMPLETED Phase 2 12 participants

PXD101 in Treating Patients With Acute Myeloid Leukemia

National Cancer Institute (NCI)

NCT00357032

COMPLETED Phase 1 8 participants

Decitabine, Donor Natural Killer Cells, and Aldesleukin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Sumithira Vasu

NCT02316964

Phase Distribution

PhaseTrial count
Phase 1 15
Phase 2 4

Named interventions

Most-linked intervention names on Recurrent Adult Acute Myeloid Leukemia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Laboratory Biomarker Analysis Other
8 trials
Cytarabine Drug
6 trials
laboratory biomarker analysis Other
5 trials
Fludarabine Phosphate Drug
3 trials
Filgrastim Biological
3 trials
Decitabine Drug
3 trials
Mitoxantrone Hydrochloride Drug
2 trials
Pharmacological Study Other
2 trials

US sites by state

Facility locations filed on Recurrent Adult Acute Myeloid Leukemia trials. A trial with sites in several states counts in each.

Ohio 4 trials
California 4 trials
Washington 3 trials
Illinois 3 trials
North Carolina 2 trials
Texas 1 trials
Pennsylvania 1 trials
New York 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Recurrent Adult Acute Myeloid Leukemia page

20 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 3 Recurrent Adult Acute Myeloid Leukemia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • National Cancer Institute (NCI) sponsors the most Recurrent Adult Acute Myeloid Leukemia trials on record, review their full trial history before evaluating a specific study. See National Cancer Institute (NCI)'s trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Recurrent Adult Acute Myeloid Leukemia condition card totals 20 registered trials; most-linked intervention Laboratory Biomarker Analysis; top US site state Ohio. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.