Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Coronary Heart Disease: full-pipeline trial registry
3 of 20 indexed Coronary Heart Disease trials are currently recruiting.
Corpus placement: #848 of 28,707 conditions by registered trial count.
20 US clinical trials · 3 currently recruiting · #848 of 28,707 conditions by registered trial count
Coronary Heart Disease: 20 US clinical trials tracked, 3 recruiting.
Coronary Heart Disease is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is CardioDx, running 2 of these trials.
Enrollment posture brief
Registry condition coronary-heart-disease
OPEN 3 | RECR 15% | LATE 5 | EARLY 4 | RANK #848 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Recurrent Adult Acute Myeloid Leukemia (15% recruiting · 20 trials)
Coronary Heart Disease lists 3 open slots (15% of 20 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Coronary Heart Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Coronary Heart Disease is recruiting below its size-band peers.
3 of 20 indexed trials (15%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Coronary Heart Disease trials is spread across many organizations.
CardioDx accounts for 2 of 20 trials (10%). 18 distinct sponsors appear on at least one study for this condition label.
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Typical Coronary Heart Disease enrolment sits around 489 participants.
Median target enrolment is 489 among the 20 trials that report a genuine target (sentinel values excluded). 7 of those (35%) plan for fewer than 100 participants.
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Coronary Heart Disease research is mostly interventional.
18 interventional and 2 observational studies make up this index (90% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
20 total, page 1 of 1
Project 3: ACHIEVE- CHD
University Hospitals Cleveland Medical Center
NCT05918380
Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients
West Virginia School of Osteopathic Medicine
NCT06049420
Thiamine Intervention and Coronary Artery Bypass Grafting
University of California, Los Angeles
NCT06326996
A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome
Hoffmann-La Roche
NCT00658515
Personalized Risk Evaluation and Diagnosis (Using Corus CAD or ASGES) in the Coronary Tree
CardioDx
NCT00500617
12-week Open-label, Phase IIIb Comparing Efficacy and Safety of Rosuvastatin (CRESTOR™) in Combination With Ezetimibe
AstraZeneca
NCT00525824
Evaluate Safety and Efficacy of ABT-335 in Combination With Rosuvastatin Calcium in Subjects With Multiple Abnormal Lipid Levels in the Blood
Abbott
NCT00300482
Cholesterol and Pharmacogenetic Study
UCSF Benioff Children's Hospital Oakland
NCT00451828
Safety and Efficacy Study Using ABT-335 (Investigational Drug) in Combination With Atorvastatin, to Study the Effects on Thickening of the Blood Vessel Wall in Patients With Abnormal Lipid (Fat) Levels in the Blood
AbbVie (prior sponsor, Abbott)
NCT00616772
Coronary Obstruction Detection by Molecular Personalized Gene Expression (Corus CAD or ASGES)
CardioDx
NCT01117506
Efficacy and Safety of the ACAT Inhibitor CS-505 (Pactimibe) for Reducing the Progression of Coronary Artery Disease
Daiichi Sankyo
NCT00185042
Heart to Health: A Combined Lifestyle and Medication Intervention to Reduce Cardiovascular Disease (CVD) Risk
University of North Carolina, Chapel Hill
NCT01245686
An IT Approach to Implementing Depression Treatment in Cardiac Patients (iHeart DepCare)
Columbia University
NCT03882411
Slowing HEART diSease With Lifestyle and Omega-3 Fatty Acids
Beth Israel Deaconess Medical Center
NCT01624727
A Study of the Effect of RO4607381 on Atherosclerotic Plaque in Patients With Coronary Heart Disease
Hoffmann-La Roche
NCT00655473
A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 and MAS825 for Inflammatory Marker Reduction in Adult Participants With Coronary Heart Disease and Clonal Hematopoiesis of Indeterminate Potential (CHIP)
Novartis Pharmaceuticals
NCT06097663
Walnut Consumption, Endothelial Function, and Biomarkers
Brigham and Women's Hospital
NCT01884363
Study of the Arachidonate 5-Lipoxygenase Enzyme in Affecting the Risk for Coronary Heart Disease
University of Florida
NCT00379808
Developing and Evaluating an Indoor Air Pollution Intervention Among Cardiovascular Patients: the AIRWISE Study
University of Montana
NCT06384625
Relationship Between the Menstrual Cycle and Heart Disease in Women
Oregon Health and Science University
NCT01546454
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
| Phase 3 | 4 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Coronary Heart Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Coronary Heart Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Coronary Heart Disease page
20 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Coronary Heart Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- CardioDx sponsors the most Coronary Heart Disease trials on record, review their full trial history before evaluating a specific study. See CardioDx's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Coronary Heart Disease condition card totals 20 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.