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NCT02204085 · ClinicalTrials.gov registry record · Phase 1

A Phase I/II Trial of the MUC1 Inhibitor, GO-203-2C in Patients With Relapsed or Refractory Acute Myeloid Leukemia

A Phase 1 study of Recurrent Adult Acute Myeloid Leukemia and Acute Myeloid Leukemia, in Relapse, sponsored by Beth Israel Deaconess Medical Center.

Active
Registry status
Phase 1
Development phase
33
Enrollment target
2
Study locations

NCT02204085 is a Phase 1 study of Recurrent Adult Acute Myeloid Leukemia and Acute Myeloid Leukemia, in Relapse that is active but no longer recruiting, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 33 participants, below the 53-participant average among 19 other Recurrent Adult Acute Myeloid Leukemia trials with a reported enrollment target (38% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT02204085, a Phase 1 study of Recurrent Adult Acute Myeloid Leukemia and Acute Myeloid Leukemia, in Relapse, is active but no longer recruiting, sponsored by Beth Israel Deaconess Medical Center.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
33 participants
Enrollment target
2
Study locations

Study Summary

This research study is studying a targeted therapy known as GO-203-2C as a possible treatment for with acute myeloid leukemia (AML) both alone and in combination with decitabine. GO-203-2c targets cancer cells, while leaving healthy cells unaffected.This is a Phase I/II clinical trial. A Phase I clinical trial tests the safety of an investigational intervention and also tries to define the appropriate dose of the investigational intervention to use for further studies.

Interventions

  • DRUG GO-203-2c
  • DRUG GO-203-2c + Decitabine

Study Locations (2)

Massachusetts

  • Dana-Farber Cancer Institute - Boston
  • Beth Israel Deaconess Medical Center - Boston

Trial Details

FieldValue
Enrollment Target 33 participants
Start Date 2014-09
Est. Completion 2025-12
Phase Phase 1

What the Registry Record Tells You About NCT02204085

The ClinicalTrials.gov registry entry for NCT02204085 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 33 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 53-participant average among 19 other Recurrent Adult Acute Myeloid Leukemia trials with a reported enrollment target (38% lower). The listed sponsor is Beth Israel Deaconess Medical Center, which has 488 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Recurrent Adult Acute Myeloid Leukemia appearing as the primary indexed condition, and to 2 interventions - of which GO-203-2c is the first listed.

NCT02204085 reports 2 study locations spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT02204085 about?

NCT02204085 is a clinical study titled "A Phase I/II Trial of the MUC1 Inhibitor, GO-203-2C in Patients With Relapsed or Refractory Acute Myeloid Leukemia". This research study is studying a targeted therapy known as GO-203-2C as a possible treatment for with acute myeloid leukemia (AML) both alone and in combination with decitabine. GO-203-2c targets cancer cells, while leaving healthy cells unaffected.This is a Phase I/II clinical trial. A Phase I cli...

What is the current status of trial NCT02204085?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 33 participants. The study started on 2014-09. Estimated completion is 2025-12.

What conditions does trial NCT02204085 study?

This clinical trial studies the following conditions: Recurrent Adult Acute Myeloid Leukemia, Acute Myeloid Leukemia, in Relapse.

What interventions are being tested in trial NCT02204085?

The interventions under investigation include: GO-203-2c (DRUG), GO-203-2c + Decitabine (DRUG).

Who is sponsoring clinical trial NCT02204085?

This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02204085 being conducted?

This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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