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ACL Reconstruction clinical trials
4 of 5 indexed ACL Reconstruction trials are currently recruiting.
5 US clinical trials · 4 currently recruiting
ACL Reconstruction is the subject of 5 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. The most active sponsor is Illinois Center for Orthopaedic Research and Education, running 1 of these trials.
The research picture
ACL Reconstruction has 5 registered US clinical trials, 4 of them open to new participants right now, about 80% of the total.
- 4
- recruiting participants now
- 80%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 1
- top sponsor: Illinois Center for Orthopaedic Research and Education
Active & Recent Trials
5 total, page 1 of 1
Does Blood Flow Restriction Training Improve Quadriceps Function After Arthroscopic Knee Surgery?
The University of Texas Health Science Center, Houston
NCT03096366
A Comparison of Outcomes After Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) Surgery Using Semiconductor Fabric Products
Illinois Center for Orthopaedic Research and Education
NCT06979804
Protein Supplementation After ACL Surgery
The Methodist Hospital Research Institute
NCT06311058
Effect of Internal Brace on Outcomes Following ACL Reconstruction With BTB Autograft
NYU Langone Health
NCT06542705
When do School-aged Patients Return to School After ACL Surgery?
St. Louis University
NCT03929237
Phase Distribution
Phase data not available
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the ACL Reconstruction Trial Landscape
5 indexed ACL Reconstruction studies · 4 recruiting (80%).
Phase mix: 0 late (III/IV) vs 0 early (I/II).
Top sponsor: Illinois Center for Orthopaedic Research and Education (1 trial), 4 others listed. 5 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for ACL Reconstruction?
PlainTrial tracks 5 US clinical trials for ACL Reconstruction, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for ACL Reconstruction?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.