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ClinicalTrials.gov 11 recruiting now later-stage tilt

Prediabetic State: later-stage trial registry

11 of 24 indexed Prediabetic State trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #686 of 28,707 conditions by registered trial count.

24 US clinical trials · 11 currently recruiting · #686 of 28,707 conditions by registered trial count

Prediabetic State: 24 US clinical trials tracked, 11 recruiting.

Prediabetic State is the subject of 24 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Columbia University, running 2 of these trials.

Enrollment posture brief

Registry condition prediabetic-state

OPEN 11 | RECR 46% | LATE 3 | EARLY 1 | RANK #686 | SPON 2

Nearest open-share peer: Glaucoma Open-Angle (46% recruiting · 24 trials)

Prediabetic State (this)46%Aplastic Anemia37.5%Behavior37.5%Allergic Rhinitis8.3%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Prediabetic State

Prediabetic State lists 11 open slots (46% of 24 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Prediabetic State on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Prediabetic State is recruiting above its size-band peers.

    11 of 24 indexed trials (45.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Prediabetic State trials is spread across many organizations.

    Columbia University accounts for 2 of 24 trials (8.3%). 20 distinct sponsors appear on at least one study for this condition label.

  3. Typical Prediabetic State enrolment sits around 120 participants.

    Median target enrolment is 120 among the 24 trials that report a genuine target (sentinel values excluded). 11 of those (45.8%) plan for fewer than 100 participants.

  4. Prediabetic State research is mostly interventional.

    22 interventional and 2 observational studies make up this index (91.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 43

Open and recent trials

24 total, page 1 of 1

RECRUITING Phase 4 7,410 participants

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

VA Office of Research and Development

NCT02915198

RECRUITING 850 participants

Wake Forest Alzheimer's Disease Clinical Core

Wake Forest University Health Sciences

NCT03140865

RECRUITING NA 324 participants

PreventT2 Together: Examining the Efficacy of Couple-based Lifestyle Intervention to Prevent Type 2 Diabetes

University of Utah

NCT06690788

RECRUITING NA 300 participants

Sleep for Health Study on the Effects of Cognitive Behavioral Therapy for Insomnia on Diabetes Risk

Kaiser Permanente

NCT06067139

RECRUITING NA 216 participants

The GRoceries Aimed at Increasing Nutrition Study

University of Pennsylvania

NCT07167004

RECRUITING Phase 4 200 participants

Effect of Zinc on Glucose Homeostasis

University of Maryland, Baltimore

NCT05835037

RECRUITING NA 120 participants

Exercise Training and Fat Metabolism in Postmenopausal Women

Florida State University

NCT05351476

RECRUITING NA 54 participants

Heat and Exercise in Aging as Therapy (HEAT)

Texas Tech University

NCT06580964

RECRUITING Phase 1 32 participants

Human Models of Selective Insulin Resistance: Alpelisib, Part I

Columbia University

NCT06354088

RECRUITING NA 26 participants

Role of Aging and Individual Variation in Exercise Training Responsiveness

Duke University

NCT06471569

RECRUITING NA 20 participants

Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center

Cedars-Sinai Medical Center

NCT06897982

ACTIVE NOT RECRUITING 500 participants

Evaluation of a Telehealth DPP With Medicare Patients at the University of Mississippi Medical Center

University of Mississippi Medical Center

NCT04822480

ACTIVE NOT RECRUITING Phase 4 60 participants

Use of Empagliflozin to Treat Prediabetes

Oregon State University

NCT05426525

ACTIVE NOT RECRUITING NA 20 participants

Enhancing Mental and Physical Health of Women Veterans

VA Office of Research and Development

NCT05050266

COMPLETED NA 1,500 participants

Minnesota Medicaid Incentives to Prevent Chronic Disease

Minnesota Department of Human Services

NCT02422420

COMPLETED NA 521 participants

A Pharmacist-Coordinated Implementation of the Diabetes Prevention Program

University of California, Los Angeles

NCT02384109

COMPLETED NA 300 participants

Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients

Massachusetts General Hospital

NCT02551640

COMPLETED NA 163 participants

Text Messaging for Weight Loss

Denver Health and Hospital Authority

NCT02063048

COMPLETED NA 101 participants

Undiagnosed Diabetes in a Dental Setting

Columbia University

NCT01711385

COMPLETED NA 72 participants

Feasibility of a Partnered Approach to Prevent Diabetes

Northwestern University

NCT00302055

COMPLETED NA 69 participants

A Mobile Phone-based Program for Adults With Prediabetes

University of Michigan

NCT03025607

COMPLETED NA 60 participants

Macronutrient Effects on Alzheimer's Disease (MEAL-2)

Wake Forest University Health Sciences

NCT02463084

COMPLETED NA 39 participants

RCT of a Polyherbal Dietary Supplement for Prediabetes

University of Maryland, Baltimore

NCT03388762

COMPLETED NA 30 participants

Feasibility and Preliminary Effects of Fasting-Mimicking Diet in Asian Americans With Prediabetes

University of California, Irvine

NCT06518798

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 4 3

Named interventions

Most-linked intervention names on Prediabetic State records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
3 trials
FeatForward App (on study smartphone) Other
1 trials
Text Message Based Weight Loss Support Behavioral
1 trials
Standard care from primary care providers Other
1 trials
Shared decision-making with pharmacists Behavioral
1 trials
Enhanced intervention Behavioral
1 trials
JOOL Health Mobile Phone Application Device
1 trials
GlucoSupreme™ Herbal Dietary supplement
1 trials

US sites by state

Facility locations filed on Prediabetic State trials. A trial with sites in several states counts in each.

California 5 trials
North Carolina 3 trials
Pennsylvania 2 trials
Oregon 2 trials
New York 2 trials
Maryland 2 trials
Florida 2 trials
Colorado 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Prediabetic State page

24 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Prediabetic State condition card totals 24 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.