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Prediabetic State clinical trials
10 of 22 indexed Prediabetic State trials are currently recruiting.
22 US clinical trials · 10 currently recruiting
Prediabetic State is the subject of 22 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Columbia University, running 2 of these trials.
The research picture
Prediabetic State has 22 registered US clinical trials, 10 of them open to new participants right now, about 45% of the total.
- 10
- recruiting participants now
- 45%
- of trials open to enrollment
- 3
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Columbia University
Active & Recent Trials
22 total, page 1 of 1
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes
VA Office of Research and Development
NCT02915198
Wake Forest Alzheimer's Disease Clinical Core
Wake Forest University Health Sciences
NCT03140865
PreventT2 Together: Examining the Efficacy of Couple-based Lifestyle Intervention to Prevent Type 2 Diabetes
University of Utah
NCT06690788
Sleep for Health Study on the Effects of Cognitive Behavioral Therapy for Insomnia on Diabetes Risk
Kaiser Permanente
NCT06067139
Effect of Zinc on Glucose Homeostasis
University of Maryland, Baltimore
NCT05835037
Exercise Training and Fat Metabolism in Postmenopausal Women
Florida State University
NCT05351476
Heat and Exercise in Aging as Therapy (HEAT)
Texas Tech University
NCT06580964
Human Models of Selective Insulin Resistance: Alpelisib, Part I
Columbia University
NCT06354088
Role of Aging and Individual Variation in Exercise Training Responsiveness
Duke University
NCT06471569
Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center
Cedars-Sinai Medical Center
NCT06897982
Evaluation of a Telehealth DPP With Medicare Patients at the University of Mississippi Medical Center
University of Mississippi Medical Center
NCT04822480
Use of Empagliflozin to Treat Prediabetes
Oregon State University
NCT05426525
Enhancing Mental and Physical Health of Women Veterans
VA Office of Research and Development
NCT05050266
Minnesota Medicaid Incentives to Prevent Chronic Disease
Minnesota Department of Human Services
NCT02422420
A Pharmacist-Coordinated Implementation of the Diabetes Prevention Program
University of California, Los Angeles
NCT02384109
Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients
Massachusetts General Hospital
NCT02551640
Text Messaging for Weight Loss
Denver Health and Hospital Authority
NCT02063048
Undiagnosed Diabetes in a Dental Setting
Columbia University
NCT01711385
A Mobile Phone-based Program for Adults With Prediabetes
University of Michigan
NCT03025607
Macronutrient Effects on Alzheimer's Disease (MEAL-2)
Wake Forest University Health Sciences
NCT02463084
RCT of a Polyherbal Dietary Supplement for Prediabetes
University of Maryland, Baltimore
NCT03388762
Feasibility and Preliminary Effects of Fasting-Mimicking Diet in Asian Americans With Prediabetes
University of California, Irvine
NCT06518798
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Prediabetic State Trial Landscape
22 indexed Prediabetic State studies · 10 recruiting (45%).
Phase mix: 3 late (III/IV) vs 1 early (I/II).
Top sponsor: Columbia University (2 trials), 9 others listed. 22 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Prediabetic State?
PlainTrial tracks 22 US clinical trials for Prediabetic State, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Prediabetic State?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.