Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Prediabetic State

Open-data reference.

22 US clinical trials · 10 currently recruiting

Active & Recent Trials

RECRUITING Phase 4 7,410 participants

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

VA Office of Research and Development

NCT02915198

RECRUITING 850 participants

Wake Forest Alzheimer's Disease Clinical Core

Wake Forest University Health Sciences

NCT03140865

RECRUITING NA 324 participants

PreventT2 Together: Examining the Efficacy of Couple-based Lifestyle Intervention to Prevent Type 2 Diabetes

University of Utah

NCT06690788

RECRUITING NA 300 participants

Sleep for Health Study on the Effects of Cognitive Behavioral Therapy for Insomnia on Diabetes Risk

Kaiser Permanente

NCT06067139

RECRUITING Phase 4 200 participants

Effect of Zinc on Glucose Homeostasis

University of Maryland, Baltimore

NCT05835037

RECRUITING NA 120 participants

Exercise Training and Fat Metabolism in Postmenopausal Women

Florida State University

NCT05351476

RECRUITING NA 54 participants

Heat and Exercise in Aging as Therapy (HEAT)

Texas Tech University

NCT06580964

RECRUITING Phase 1 32 participants

Human Models of Selective Insulin Resistance: Alpelisib, Part I

Columbia University

NCT06354088

RECRUITING NA 26 participants

Role of Aging and Individual Variation in Exercise Training Responsiveness

Duke University

NCT06471569

RECRUITING NA 20 participants

Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center

Cedars-Sinai Medical Center

NCT06897982

ACTIVE NOT RECRUITING 500 participants

Evaluation of a Telehealth DPP With Medicare Patients at the University of Mississippi Medical Center

University of Mississippi Medical Center

NCT04822480

ACTIVE NOT RECRUITING Phase 4 60 participants

Use of Empagliflozin to Treat Prediabetes

Oregon State University

NCT05426525

ACTIVE NOT RECRUITING NA 20 participants

Enhancing Mental and Physical Health of Women Veterans

VA Office of Research and Development

NCT05050266

COMPLETED NA 1,500 participants

Minnesota Medicaid Incentives to Prevent Chronic Disease

Minnesota Department of Human Services

NCT02422420

COMPLETED NA 521 participants

A Pharmacist-Coordinated Implementation of the Diabetes Prevention Program

University of California, Los Angeles

NCT02384109

COMPLETED NA 300 participants

Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients

Massachusetts General Hospital

NCT02551640

COMPLETED NA 163 participants

Text Messaging for Weight Loss

Denver Health and Hospital Authority

NCT02063048

COMPLETED NA 101 participants

Undiagnosed Diabetes in a Dental Setting

Columbia University

NCT01711385

COMPLETED NA 69 participants

A Mobile Phone-based Program for Adults With Prediabetes

University of Michigan

NCT03025607

COMPLETED NA 60 participants

Macronutrient Effects on Alzheimer's Disease (MEAL-2)

Wake Forest University Health Sciences

NCT02463084

COMPLETED NA 39 participants

RCT of a Polyherbal Dietary Supplement for Prediabetes

University of Maryland, Baltimore

NCT03388762

COMPLETED NA 30 participants

Feasibility and Preliminary Effects of Fasting-Mimicking Diet in Asian Americans With Prediabetes

University of California, Irvine

NCT06518798

Phase Distribution

PhaseTrial count
Early Phase 1 1
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Prediabetic State Trial Landscape

ClinicalTrials.gov lists 22 US studies indexed under Prediabetic State, and 10 of those are currently open to recruitment — roughly 45% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Prediabetic State shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Prediabetic State is led by Columbia University with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 22 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Prediabetic State?

PlainTrial tracks 22 US clinical trials for Prediabetic State, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Prediabetic State?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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