Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
POTS - Postural Orthostatic Tachycardia Syndrome: early-phase trial registry
3 of 6 indexed POTS - Postural Orthostatic Tachycardia Syndrome trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,866 of 28,707 conditions by registered trial count.
6 US clinical trials · 3 currently recruiting · #2,866 of 28,707 conditions by registered trial count
POTS - Postural Orthostatic Tachycardia Syndrome: 6 US clinical trials tracked, 3 recruiting.
POTS - Postural Orthostatic Tachycardia Syndrome is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Vanderbilt University Medical Center, running 2 of these trials.
Enrollment posture brief
Registry condition pots-postural-orthostatic-tachycardia-syndrome
OPEN 3 | RECR 50% | LATE 0 | EARLY 1 | RANK #2866 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Achalasia (50% recruiting · 8 trials)
POTS - Postural Orthostatic Tachycardia Syndrome lists 3 open slots (50% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for POTS - Postural Orthostatic Tachycardia Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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POTS - Postural Orthostatic Tachycardia Syndrome is recruiting above its size-band peers.
3 of 6 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates POTS - Postural Orthostatic Tachycardia Syndrome research.
Vanderbilt University Medical Center accounts for 2 of 6 trials (33.3%). 5 distinct sponsors appear on at least one study for this condition label.
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Typical POTS - Postural Orthostatic Tachycardia Syndrome enrolment sits around 100 participants.
Median target enrolment is 100 among the 6 trials that report a genuine target (sentinel values excluded). 3 of those (50%) plan for fewer than 100 participants.
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POTS - Postural Orthostatic Tachycardia Syndrome research is mostly interventional.
5 interventional and 1 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
6 total, page 1 of 1
Long COVID Immune Profiling
Vanderbilt University Medical Center
NCT06027255
Does a Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Nat hx With Its Numerous Co-morbidities?
Virginia Commonwealth University
NCT06616363
Restoring Iron Deficiency in POTS
Vanderbilt University Medical Center
NCT07197905
Pathophysiology of Dysautonomia and Postural Tachycardia Syndrome (POTS) in Post-viral Syndromes and COVID-19
Brigham and Women's Hospital
NCT07405515
Non-invasive Vagal Neurostimulation (nVNS) in Adolescents With Postural Orthostatic Tachycardia Syndrome (POTS)
Mayo Clinic
NCT06268288
A MHealth System for Patients with POTS
Jami Warren
NCT06296914
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on POTS - Postural Orthostatic Tachycardia Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on POTS - Postural Orthostatic Tachycardia Syndrome trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this POTS - Postural Orthostatic Tachycardia Syndrome page
6 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 POTS - Postural Orthostatic Tachycardia Syndrome trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Vanderbilt University Medical Center sponsors the most POTS - Postural Orthostatic Tachycardia Syndrome trials on record, review their full trial history before evaluating a specific study. See Vanderbilt University Medical Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This POTS - Postural Orthostatic Tachycardia Syndrome condition card totals 6 registered trials; most-linked intervention STEPS management protocol; top US site state Tennessee. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.