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NCT06027255 · ClinicalTrials.gov registry record · NA
Long COVID Immune Profiling
A NA study of Long COVID and Autonomic Dysfunction, sponsored by Vanderbilt University Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 150
- Enrollment target
- 1
- Study location
NCT06027255 is a NA study of Long COVID and Autonomic Dysfunction that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 150 participants, below the 2,185-participant average among 50 other Long COVID trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06027255, a NA study of Long COVID and Autonomic Dysfunction, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
Parasympathetic nervous system (PNS) is part of the body's autonomic nervous system(PNS) protects body against inflammation. Study shows that reduced PNS function activity is associated with persistent inflammation. Preliminary data from the studies shows, that post-COVID-19 POTS patients have reduced parasympathetic (PNS) function. Given that the PNS protects against inflammation, this clinical trial aims to prove that post-COVID-19 POTS is caused by reduced PNS activity, which in turn, contributes to persistent inflammation, orthostatic intolerance, and OI symptoms. The study will evaluate immune cell activation in post-COVID-19 POTS and patients with history of COVID-19 infection without sequelae and correlate this with the degree of decreased PNS activity.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST IL-6
- DIAGNOSTIC_TEST cytokines (IL-17, and IFN-ɣ)
- BEHAVIORAL Compass 31
Study Locations (1)
Tennessee
- Cyndya Shibao - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2024-04-24 |
| Est. Completion | 2027-07-01 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06027255
The ClinicalTrials.gov registry entry for NCT06027255 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,185-participant average among 50 other Long COVID trials with a reported enrollment target (93% lower). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Long COVID appearing as the primary indexed condition, and to 3 interventions - of which IL-6 is the first listed.
NCT06027255 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.
Frequently Asked Questions
What is clinical trial NCT06027255 about?
NCT06027255 is a clinical study titled "Long COVID Immune Profiling". Parasympathetic nervous system (PNS) is part of the body's autonomic nervous system(PNS) protects body against inflammation. Study shows that reduced PNS function activity is associated with persistent inflammation. Preliminary data from the studies shows, that post-COVID-19 POTS patients have redu...
What is the current status of trial NCT06027255?
This trial is currently recruiting. It is a NA study. The enrollment target is 150 participants. The study started on 2024-04-24. Estimated completion is 2027-07-01.
What conditions does trial NCT06027255 study?
This clinical trial studies the following conditions: Long COVID, Autonomic Dysfunction, POTS - Postural Orthostatic Tachycardia Syndrome.
What interventions are being tested in trial NCT06027255?
The interventions under investigation include: IL-6 (DIAGNOSTIC_TEST), cytokines (IL-17, and IFN-ɣ) (DIAGNOSTIC_TEST), Compass 31 (BEHAVIORAL).
Who is sponsoring clinical trial NCT06027255?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06027255 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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