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NCT07197905 · ClinicalTrials.gov registry record · Phase 2

Restoring Iron Deficiency in POTS

A Phase 2 study of POTS - Postural Orthostatic Tachycardia Syndrome, sponsored by Vanderbilt University Medical Center.

Recruiting
Registry status
Phase 2
Development phase
12
Enrollment target
1
Study location

NCT07197905 is a Phase 2 study of POTS - Postural Orthostatic Tachycardia Syndrome that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 12 participants, below the 86-participant average among 5 other POTS - Postural Orthostatic Tachycardia Syndrome trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07197905, a Phase 2 study of POTS - Postural Orthostatic Tachycardia Syndrome, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.

RECRUITING
Registry status
Phase 2
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

People with postural orthostatic tachycardia syndrome (POTS) often have low red blood cell volumes and low ferritin in their blood (a marker of iron storage in the body). The purpose of this pilot study is to investigate whether giving iron to people with POTS who have low ferritin levels will increase the red blood cell volume and improve POTS symptoms.

Interventions

  • DRUG Intravenous iron

Study Locations (1)

Tennessee

  • Autonomic Dysfunction Center/ Vanderbilt University Medical Center - Nashville

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2025-11-24
Est. Completion 2026-12
Phase Phase 2

What the Registry Record Tells You About NCT07197905

The ClinicalTrials.gov registry entry for NCT07197905 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 86-participant average among 5 other POTS - Postural Orthostatic Tachycardia Syndrome trials with a reported enrollment target (86% lower). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with POTS - Postural Orthostatic Tachycardia Syndrome appearing as the primary indexed condition, and to 1 intervention - of which Intravenous iron is the first listed.

NCT07197905 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.

Frequently Asked Questions

What is clinical trial NCT07197905 about?

NCT07197905 is a clinical study titled "Restoring Iron Deficiency in POTS". People with postural orthostatic tachycardia syndrome (POTS) often have low red blood cell volumes and low ferritin in their blood (a marker of iron storage in the body). The purpose of this pilot study is to investigate whether giving iron to people with POTS who have low ferritin levels will incre...

What is the current status of trial NCT07197905?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2025-11-24. Estimated completion is 2026-12.

What conditions does trial NCT07197905 study?

This clinical trial studies the following conditions: POTS - Postural Orthostatic Tachycardia Syndrome.

What interventions are being tested in trial NCT07197905?

The interventions under investigation include: Intravenous iron (DRUG).

Who is sponsoring clinical trial NCT07197905?

This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07197905 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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