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NCT07197905 · ClinicalTrials.gov registry record · Phase 2
Restoring Iron Deficiency in POTS
A Phase 2 study of POTS - Postural Orthostatic Tachycardia Syndrome, sponsored by Vanderbilt University Medical Center.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT07197905: Recruiting Phase 2 study of POTS - Postural Orthostatic Tachycardia Syndrome, sponsored by Vanderbilt University Medical Center.
NCT07197905 is a Phase 2 study of POTS - Postural Orthostatic Tachycardia Syndrome that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 12 participants, below the 86-participant average among 5 other POTS - Postural Orthostatic Tachycardia Syndrome trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07197905, a Phase 2 study of POTS - Postural Orthostatic Tachycardia Syndrome, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
People with postural orthostatic tachycardia syndrome (POTS) often have low red blood cell volumes and low ferritin in their blood (a marker of iron storage in the body). The purpose of this pilot study is to investigate whether giving iron to people with POTS who have low ferritin levels will increase the red blood cell volume and improve POTS symptoms.
Primary Outcome
Orthostatic tachycardia, defined as the difference between upright and supine heart rates, will be assessed during a 10-minute head-up tilt test.
Conditions Studied
Interventions
- DRUG Intravenous iron
Study Locations (1)
Tennessee
- Autonomic Dysfunction Center/ Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2025-11-24 |
| Est. Completion | 2026-12 |
| Phase | Phase 2 |
What NCT07197905 shows while recruiting
NCT07197905 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 86-participant average among 5 other POTS - Postural Orthostatic Tachycardia Syndrome trials with a reported enrollment target (86% lower).
The record links to 1 condition, with POTS - Postural Orthostatic Tachycardia Syndrome appearing as the primary indexed condition, and to 1 intervention - of which Intravenous iron is the first listed.
NCT07197905 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT07197905 about?
NCT07197905 is a clinical study titled "Restoring Iron Deficiency in POTS". People with postural orthostatic tachycardia syndrome (POTS) often have low red blood cell volumes and low ferritin in their blood (a marker of iron storage in the body). The purpose of this pilot study is to investigate whether giving iron to people with POTS who have low ferritin levels will incre...
What is the current status of trial NCT07197905?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2025-11-24. Estimated completion is 2026-12.
What conditions does trial NCT07197905 study?
This clinical trial studies the following conditions: POTS - Postural Orthostatic Tachycardia Syndrome.
What interventions are being tested in trial NCT07197905?
The interventions under investigation include: Intravenous iron (DRUG).
Who is sponsoring clinical trial NCT07197905?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07197905 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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