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Post Acute Sequelae of COVID-19 clinical trials
5 of 9 indexed Post Acute Sequelae of COVID-19 trials are currently recruiting.
9 US clinical trials · 5 currently recruiting
Post Acute Sequelae of COVID-19 is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 2 of these trials.
The research picture
Post Acute Sequelae of COVID-19 has 9 registered US clinical trials, 5 of them open to new participants right now, about 56% of the total.
- 5
- recruiting participants now
- 56%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Massachusetts General Hospital
Active & Recent Trials
9 total, page 1 of 1
COVID-19 Outcome Prediction Algorithm
University of California, Los Angeles
NCT05471011
Autoimmune Intervention Mastery Course Study
Terry L. Wahls
NCT05057676
Mind Body Intervention for Long COVID-19
Beth Israel Deaconess Medical Center
NCT06045338
AT1001 for the Treatment of Long COVID
Massachusetts General Hospital
NCT05747534
PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)
National Institute of Mental Health (NIMH)
NCT06920628
Ensitrelvir for Viral Persistence and Inflammation in People Experiencing Long COVID
Timothy Henrich
NCT06161688
Home-based Brain Stimulation Treatment for Post-acute Sequelae of COVID-19 (PASC)
Massachusetts General Hospital
NCT05092516
Glutamatergic Modulation as a Treatment for Depressive Symptoms Among Patients With Post-acute Sequelae of COVID (PASC): A Pilot Trial
New York State Psychiatric Institute
NCT05690503
Diaphragmatic Breathing Exercises for Post-COVID-19 Diaphragmatic Dysfunction (DD)
University of Minnesota
NCT06330376
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Post Acute Sequelae of COVID-19 Trial Landscape
9 indexed Post Acute Sequelae of COVID-19 studies · 5 recruiting (56%).
Phase mix: 0 late (III/IV) vs 4 early (I/II).
Top sponsor: Massachusetts General Hospital (2 trials), 7 others listed. 9 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Post Acute Sequelae of COVID-19?
PlainTrial tracks 9 US clinical trials for Post Acute Sequelae of COVID-19, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Post Acute Sequelae of COVID-19?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.