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NCT06161688 · ClinicalTrials.gov registry record · Phase 2

Ensitrelvir for Viral Persistence and Inflammation in People Experiencing Long COVID

A Phase 2 study of Long COVID and Post Acute Sequelae of COVID-19, sponsored by Timothy Henrich.

Active
Registry status
Phase 2
Development phase
40
Enrollment target
1
Study location

NCT06161688 is a Phase 2 study of Long COVID and Post Acute Sequelae of COVID-19 that is active but no longer recruiting, run by Timothy Henrich. The registered enrollment target is 40 participants, below the 2,187-participant average among 50 other Long COVID trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06161688, a Phase 2 study of Long COVID and Post Acute Sequelae of COVID-19, is active but no longer recruiting, sponsored by Timothy Henrich.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

Persistent viral infection with viral reservoirs and detection of circulating spike protein after the initial acute illness is one potential pathogenic mechanism for Long COVID. This mechanism may be susceptible to antiviral therapy that blocks viral replication, which has the potential to alleviate long COVID symptoms. This trial will study the safety and efficacy of Ensitrelvir (S-217622), an antiviral, to treat individuals with Long COVID in an adult population.

Conditions Studied

Long COVID Post Acute Sequelae of COVID-19 Post-Acute COVID-19

Interventions

  • OTHER Placebo
  • DRUG Ensitrelvir

Study Locations (1)

California

  • UCSF/Zuckerberg San Francisco General Hospital - San Francisco

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2024-04-09
Est. Completion 2025-12-31
Phase Phase 2

Sponsor

Timothy Henrich

1 total trials

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What the Registry Record Tells You About NCT06161688

The ClinicalTrials.gov registry entry for NCT06161688 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,187-participant average among 50 other Long COVID trials with a reported enrollment target (98% lower). The listed sponsor is Timothy Henrich, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Long COVID appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06161688 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT06161688 about?

NCT06161688 is a clinical study titled "Ensitrelvir for Viral Persistence and Inflammation in People Experiencing Long COVID". Persistent viral infection with viral reservoirs and detection of circulating spike protein after the initial acute illness is one potential pathogenic mechanism for Long COVID. This mechanism may be susceptible to antiviral therapy that blocks viral replication, which has the potential to alleviate...

What is the current status of trial NCT06161688?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2024-04-09. Estimated completion is 2025-12-31.

What conditions does trial NCT06161688 study?

This clinical trial studies the following conditions: Long COVID, Post Acute Sequelae of COVID-19, Post-Acute COVID-19.

What interventions are being tested in trial NCT06161688?

The interventions under investigation include: Placebo (OTHER), Ensitrelvir (DRUG).

Who is sponsoring clinical trial NCT06161688?

This trial is sponsored by Timothy Henrich, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06161688 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.