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ClinicalTrials.gov 3 recruiting now official registry

Portal Hypertension clinical trials

3 of 10 indexed Portal Hypertension trials are currently recruiting.

10 US clinical trials · 3 currently recruiting

Portal Hypertension is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is University of Michigan, running 2 of these trials.

The research picture

Portal Hypertension has 10 registered US clinical trials, 3 of them open to new participants right now, about 30% of the total.

3
recruiting participants now
30%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
2
top sponsor: University of Michigan
Phase 21Phase 34

Active & Recent Trials

10 total, page 1 of 1

RECRUITING Phase 3 660 participants

Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension; Renewal

Thomas Jefferson University

NCT05470205

RECRUITING NA 60 participants

Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension

Mayo Clinic

NCT06797193

RECRUITING 45 participants

Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver Cirrhosis

Massachusetts General Hospital

NCT06265272

ACTIVE NOT RECRUITING 52 participants

LiveSMART Trial to Prevent Falls in Patients With Cirrhosis - Supplementary Study

University of Michigan

NCT07140120

ACTIVE NOT RECRUITING Phase 2 30 participants

Durvalumab (MEDI4736) and Tremelimumab for Hepatocellular Carcinoma in Patients Listed for a Liver Transplant

Davendra Sohal

NCT05027425

COMPLETED NA 500 participants

Non-invasive Diagnosis of Portal Hypertension With Acoustic Radiation Force Impulse (ARFI)

VA Connecticut Healthcare System

NCT01644656

COMPLETED Phase 3 230 participants

LiveSMART Trial to Prevent Falls in Patients With Cirrhosis

University of Michigan

NCT05794555

COMPLETED Phase 3 213 participants

Prevention of Esophageal Varices by Beta-Adrenergic Blockers

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00006398

COMPLETED Phase 3 70 participants

Use of Sanvar® With Endoscopic Treatment for the Control of Acute Variceal Bleeding

Debiovision

NCT00331188

COMPLETED NA 20 participants

Evaluation of 3D Overlay During Transjugular Intrahepatic Portosystemic Shunt (TIPS) Procedure

Medical College of Wisconsin

NCT02053571

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 3 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Portal Hypertension Trial Landscape

10 indexed Portal Hypertension studies · 3 recruiting (30%).

Phase mix: 4 late (III/IV) vs 1 early (I/II).

Top sponsor: University of Michigan (2 trials), 8 others listed. 10 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Portal Hypertension?

PlainTrial tracks 10 US clinical trials for Portal Hypertension, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Portal Hypertension?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.