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ClinicalTrials.gov 7 recruiting now early-phase tilt

Plasma Cell Myeloma: early-phase trial registry

7 of 33 indexed Plasma Cell Myeloma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #463 of 28,707 conditions by registered trial count.

33 US clinical trials · 7 currently recruiting · #463 of 28,707 conditions by registered trial count

Plasma Cell Myeloma: 33 US clinical trials tracked, 7 recruiting.

Plasma Cell Myeloma is the subject of 33 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 17 in Phase 1-2 (earlier-stage). The most active sponsor is Sanofi, running 4 of these trials.

Enrollment posture brief

Registry condition plasma-cell-myeloma

OPEN 7 | RECR 21% | LATE 6 | EARLY 17 | RANK #463 | SPON 4

Nearest open-share peer: Renal Impairment (21% recruiting · 33 trials)

Barrett Esophagus54.5%Clinical Stage IV Cutaneous 45.5%Child Development39.4%Anatomic Stage IIB Breast Ca24.2%Plasma Cell Myeloma (this)21%
Open-enrollment share among volume-matched conditions near Plasma Cell Myeloma

Plasma Cell Myeloma lists 7 open slots (21% of 33 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Plasma Cell Myeloma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Plasma Cell Myeloma is recruiting below its size-band peers.

    7 of 33 indexed trials (21.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Plasma Cell Myeloma trials is spread across many organizations.

    Sanofi accounts for 4 of 33 trials (12.1%). 17 distinct sponsors appear on at least one study for this condition label.

  3. Typical Plasma Cell Myeloma enrolment sits around 73 participants.

    Median target enrolment is 73 among the 33 trials that report a genuine target (sentinel values excluded). 18 of those (54.5%) plan for fewer than 100 participants.

  4. Plasma Cell Myeloma research is mostly interventional.

    28 interventional and 5 observational studies make up this index (84.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 210Phase 35Phase 41

Open and recent trials

33 total, page 1 of 1

RECRUITING Phase 3 1,450 participants

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

ECOG-ACRIN Cancer Research Group

NCT04566328

RECRUITING Phase 3 510 participants

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

SWOG Cancer Research Network

NCT05561387

RECRUITING NA 175 participants

Non-chemotherapeutic Interventions for the Improvement of Quality of Life and Immune Function in Patients With Multiple Myeloma

Roswell Park Cancer Institute

NCT05312255

RECRUITING NA 100 participants

Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

University of Southern California

NCT03858205

RECRUITING 100 participants

Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic Malignancies

M.D. Anderson Cancer Center

NCT05011045

RECRUITING Phase 2 34 participants

Belantamab Mafodotin, Pomalidomide and Dexamethasone for the Treatment of High-Risk Myeloma

Emory University

NCT05208307

RECRUITING Phase 1 20 participants

Imaging Study of [89Zr]DFO-YS5 for Detecting CD46 Positive Malignancy in Multiple Myeloma

Robert Flavell, MD, PhD

NCT05892393

ACTIVE NOT RECRUITING Phase 3 1,087 participants

Bortezomib or Carfilzomib With Lenalidomide and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma

ECOG-ACRIN Cancer Research Group

NCT01863550

ACTIVE NOT RECRUITING 583 participants

A Prospective, Non-interventional, Multinational, Observational Study With Isatuximab in Patients With Relapsed and/or Refractory Multiple Myeloma (RRMM)

Sanofi

NCT04458831

ACTIVE NOT RECRUITING Phase 3 475 participants

A Study to Investigate the Clinical Benefit of Isatuximab in Combination With Bortezomib, Lenalidomide and Dexamethasone in Adults With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant

Sanofi

NCT03319667

ACTIVE NOT RECRUITING 350 participants

Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study

City of Hope Medical Center

NCT04537871

ACTIVE NOT RECRUITING Phase 3 337 participants

Isatuximab in Combination With Lenalidomide and Dexamethasone in High-risk Smoldering Multiple Myeloma

Sanofi

NCT04270409

ACTIVE NOT RECRUITING NA 130 participants

Decision Aid Website in Helping to Make Decisions About Fertility in Participants With Cancer

M.D. Anderson Cancer Center

NCT03141437

ACTIVE NOT RECRUITING Phase 2 113 participants

Elotuzumab and Lenalidomide After Stem Cell Transplant in Treating Patients With Newly Diagnosed Multiple Myeloma

M.D. Anderson Cancer Center

NCT02420860

ACTIVE NOT RECRUITING Phase 2 108 participants

Lenalidomide Maintenance in Plasma Cell Myeloma

Memorial Sloan Kettering Cancer Center

NCT02538198

ACTIVE NOT RECRUITING Phase 2 73 participants

Study of Selinexor Plus DRd for Newly Diagnosed Multiple Myeloma

US Oncology Research

NCT04782687

ACTIVE NOT RECRUITING Phase 2 70 participants

International Treatment-extension Study in Adult Participants With Multiple Myeloma and Who Have Derived Clinical Benefit From Isatuximab

Sanofi

NCT05669989

ACTIVE NOT RECRUITING Phase 2 63 participants

SARS-CoV-2 Vaccine (GEO-CM04S1) Versus mRNA SARS-COV-2 Vaccine in Patients With Blood Cancer

GeoVax

NCT04977024

ACTIVE NOT RECRUITING 50 participants

Stopping Maintenance Therapy in People With Multiple Myeloma in MRD-Negative Remission

Memorial Sloan Kettering Cancer Center

NCT04221178

ACTIVE NOT RECRUITING Phase 2 49 participants

Daratumumab, Ixazomib, & Dexamethasone or Daratumumab, Bortezomib, & Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma

Emory University

NCT03942224

ACTIVE NOT RECRUITING Phase 1 49 participants

Iberdomide, Daratumumab, Bortezomib, and Dexamethasone for Treatment of Newly Diagnosed Multiple Myeloma, IDEAL Study

Mayo Clinic

NCT05392946

ACTIVE NOT RECRUITING Phase 2 31 participants

Daratumumab After Stem Cell Transplant in Treating Patients With Multiple Myeloma

City of Hope Medical Center

NCT03346135

ACTIVE NOT RECRUITING Phase 2 29 participants

Carfilzomib, Pomalidomide, and Dexamethasone in Treating Patients With High-Risk Multiple Myeloma

Emory University

NCT03756896

ACTIVE NOT RECRUITING Phase 1 18 participants

SVN53-67/M57-KLH Peptide Vaccine in Treating Patients With Newly Diagnosed Multiple Myeloma Receiving Lenalidomide Maintenance Therapy

Roswell Park Cancer Institute

NCT02334865

ACTIVE NOT RECRUITING Phase 2 4 participants

Belantamab Mafodotin and Lenalidomide for the Treatment of Multiple Myeloma in Patients With Minimal Residual Disease Positive After Stem Cell Transplant

Roswell Park Cancer Institute

NCT04876248

COMPLETED 375 participants

S0120, Studying Blood and Bone Marrow Samples From Patients With Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, or Plasmacytoma

SWOG Cancer Research Network

NCT00900263

COMPLETED NA 100 participants

Evaluating Effectiveness of Powered Drill Bone Marrow Biopsy

Emory University

NCT03078452

COMPLETED Phase 1 87 participants

Ixazomib With Cyclophosphamide and Dexamethasone in Patients With Previously Untreated Symptomatic Multiple Myeloma or Light Chain Amyloidosis

Mayo Clinic

NCT01864018

COMPLETED NA 25 participants

DISCO Application for the Improvement of Financial Outcomes in Patients With Hematologic Cancer

Barbara Ann Karmanos Cancer Institute

NCT04282343

COMPLETED Phase 4 20 participants

Home Based Daratumumab Administration for Patients With Multiple Myeloma

Thomas Jefferson University

NCT05511428

COMPLETED Phase 1 16 participants

MLN9708 (Ixazomib) in Combination With Panobinostat and Dexamethasone in Multiple Myeloma

Jason Valent

NCT02057640

COMPLETED Phase 1 15 participants

90 Y-BC8-DOTA Monoclonal Antibody, Fludarabine Phosphate, and Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Multiple Myeloma

Fred Hutchinson Cancer Center

NCT01503242

COMPLETED Phase 1 14 participants

Lenalidomide and Dexamethasone With or Without Anakinra in Treating Patients With Early Stage Multiple Myeloma

Mayo Clinic

NCT02492750

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 10
Phase 3 5
Phase 4 1

Named interventions

Most-linked intervention names on Plasma Cell Myeloma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Dexamethasone Drug
14 trials
Lenalidomide Drug
12 trials
Bortezomib Drug
6 trials
Questionnaire Administration Other
6 trials
Quality-of-Life Assessment Other
6 trials
Laboratory Biomarker Analysis Other
5 trials
Pomalidomide Drug
4 trials
Carfilzomib Drug
3 trials

US sites by state

Facility locations filed on Plasma Cell Myeloma trials. A trial with sites in several states counts in each.

California 11 trials
New York 8 trials
Texas 6 trials
Georgia 5 trials
Arizona 5 trials
Arkansas 5 trials
Missouri 4 trials
Minnesota 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Plasma Cell Myeloma page

33 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 7 Plasma Cell Myeloma trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Sanofi sponsors the most Plasma Cell Myeloma trials on record, review their full trial history before evaluating a specific study. See Sanofi's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Plasma Cell Myeloma condition card totals 33 registered trials; most-linked intervention Dexamethasone; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.