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2026 data Public-data reference. official source

Plasma Cell Myeloma

Open-data reference.

32 US clinical trials · 7 currently recruiting

Active & Recent Trials

RECRUITING Phase 3 1,450 participants

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

ECOG-ACRIN Cancer Research Group

NCT04566328

RECRUITING Phase 3 510 participants

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

SWOG Cancer Research Network

NCT05561387

RECRUITING NA 175 participants

Non-chemotherapeutic Interventions for the Improvement of Quality of Life and Immune Function in Patients With Multiple Myeloma

Roswell Park Cancer Institute

NCT05312255

RECRUITING NA 100 participants

Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

University of Southern California

NCT03858205

RECRUITING 100 participants

Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic Malignancies

M.D. Anderson Cancer Center

NCT05011045

RECRUITING Phase 2 34 participants

Belantamab Mafodotin, Pomalidomide and Dexamethasone for the Treatment of High-Risk Myeloma

Emory University

NCT05208307

RECRUITING Phase 1 20 participants

Imaging Study of [89Zr]DFO-YS5 for Detecting CD46 Positive Malignancy in Multiple Myeloma

Robert Flavell, MD, PhD

NCT05892393

ACTIVE NOT RECRUITING Phase 3 1,087 participants

Bortezomib or Carfilzomib With Lenalidomide and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma

ECOG-ACRIN Cancer Research Group

NCT01863550

ACTIVE NOT RECRUITING 583 participants

A Prospective, Non-interventional, Multinational, Observational Study With Isatuximab in Patients With Relapsed and/or Refractory Multiple Myeloma (RRMM)

Sanofi

NCT04458831

ACTIVE NOT RECRUITING Phase 3 475 participants

A Study to Investigate the Clinical Benefit of Isatuximab in Combination With Bortezomib, Lenalidomide and Dexamethasone in Adults With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant

Sanofi

NCT03319667

ACTIVE NOT RECRUITING 350 participants

Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study

City of Hope Medical Center

NCT04537871

ACTIVE NOT RECRUITING Phase 3 337 participants

Isatuximab in Combination With Lenalidomide and Dexamethasone in High-risk Smoldering Multiple Myeloma

Sanofi

NCT04270409

ACTIVE NOT RECRUITING NA 130 participants

Decision Aid Website in Helping to Make Decisions About Fertility in Participants With Cancer

M.D. Anderson Cancer Center

NCT03141437

ACTIVE NOT RECRUITING Phase 2 113 participants

Elotuzumab and Lenalidomide After Stem Cell Transplant in Treating Patients With Newly Diagnosed Multiple Myeloma

M.D. Anderson Cancer Center

NCT02420860

ACTIVE NOT RECRUITING Phase 2 108 participants

Lenalidomide Maintenance in Plasma Cell Myeloma

Memorial Sloan Kettering Cancer Center

NCT02538198

ACTIVE NOT RECRUITING Phase 2 73 participants

Study of Selinexor Plus DRd for Newly Diagnosed Multiple Myeloma

US Oncology Research

NCT04782687

ACTIVE NOT RECRUITING Phase 2 70 participants

International Treatment-extension Study in Adult Participants With Multiple Myeloma and Who Have Derived Clinical Benefit From Isatuximab

Sanofi

NCT05669989

ACTIVE NOT RECRUITING Phase 2 63 participants

SARS-CoV-2 Vaccine (GEO-CM04S1) Versus mRNA SARS-COV-2 Vaccine in Patients With Blood Cancer

GeoVax

NCT04977024

ACTIVE NOT RECRUITING 50 participants

Stopping Maintenance Therapy in People With Multiple Myeloma in MRD-Negative Remission

Memorial Sloan Kettering Cancer Center

NCT04221178

ACTIVE NOT RECRUITING Phase 2 49 participants

Daratumumab, Ixazomib, & Dexamethasone or Daratumumab, Bortezomib, & Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma

Emory University

NCT03942224

ACTIVE NOT RECRUITING Phase 1 49 participants

Iberdomide, Daratumumab, Bortezomib, and Dexamethasone for Treatment of Newly Diagnosed Multiple Myeloma, IDEAL Study

Mayo Clinic

NCT05392946

ACTIVE NOT RECRUITING Phase 2 31 participants

Daratumumab After Stem Cell Transplant in Treating Patients With Multiple Myeloma

City of Hope Medical Center

NCT03346135

ACTIVE NOT RECRUITING Phase 2 29 participants

Carfilzomib, Pomalidomide, and Dexamethasone in Treating Patients With High-Risk Multiple Myeloma

Emory University

NCT03756896

ACTIVE NOT RECRUITING Phase 1 18 participants

SVN53-67/M57-KLH Peptide Vaccine in Treating Patients With Newly Diagnosed Multiple Myeloma Receiving Lenalidomide Maintenance Therapy

Roswell Park Cancer Institute

NCT02334865

ACTIVE NOT RECRUITING Phase 2 4 participants

Belantamab Mafodotin and Lenalidomide for the Treatment of Multiple Myeloma in Patients With Minimal Residual Disease Positive After Stem Cell Transplant

Roswell Park Cancer Institute

NCT04876248

COMPLETED 375 participants

S0120, Studying Blood and Bone Marrow Samples From Patients With Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, or Plasmacytoma

SWOG Cancer Research Network

NCT00900263

COMPLETED NA 100 participants

Evaluating Effectiveness of Powered Drill Bone Marrow Biopsy

Emory University

NCT03078452

COMPLETED Phase 1 87 participants

Ixazomib With Cyclophosphamide and Dexamethasone in Patients With Previously Untreated Symptomatic Multiple Myeloma or Light Chain Amyloidosis

Mayo Clinic

NCT01864018

COMPLETED NA 25 participants

DISCO Application for the Improvement of Financial Outcomes in Patients With Hematologic Cancer

Barbara Ann Karmanos Cancer Institute

NCT04282343

COMPLETED Phase 4 20 participants

Home Based Daratumumab Administration for Patients With Multiple Myeloma

Thomas Jefferson University

NCT05511428

COMPLETED Phase 1 15 participants

90 Y-BC8-DOTA Monoclonal Antibody, Fludarabine Phosphate, and Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Multiple Myeloma

Fred Hutchinson Cancer Center

NCT01503242

COMPLETED Phase 1 14 participants

Lenalidomide and Dexamethasone With or Without Anakinra in Treating Patients With Early Stage Multiple Myeloma

Mayo Clinic

NCT02492750

Phase Distribution

PhaseTrial count
Early Phase 1 6
Phase 2 10
Phase 3 5
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Plasma Cell Myeloma Trial Landscape

ClinicalTrials.gov lists 32 US studies indexed under Plasma Cell Myeloma, and 7 of those are currently open to recruitment — roughly 22% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Plasma Cell Myeloma shows 6 late-stage studies (Phase 3 and Phase 4 combined) alongside 16 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Plasma Cell Myeloma is led by Sanofi with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 32 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Plasma Cell Myeloma?

PlainTrial tracks 32 US clinical trials for Plasma Cell Myeloma, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Plasma Cell Myeloma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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