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ClinicalTrials.gov 3 recruiting now later-stage tilt small index

Phantom Limb Pain: later-stage trial registry

3 of 13 indexed Phantom Limb Pain trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 3 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Phantom Limb Pain: 13 US clinical trials tracked, 3 recruiting.

Phantom Limb Pain is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Spaulding Rehabilitation Hospital, running 3 of these trials.

Enrollment posture brief

Registry condition phantom-limb-pain

OPEN 3 | RECR 23% | LATE 1 | EARLY 0 | RANK #1315 | SPON 3

Nearest open-share peer: Endometrial Serous Adenocarcinoma (23% recruiting · 13 trials)

ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Accidental Falls30.8%Actinic Keratoses23.1%Phantom Limb Pain (this)23%
Open-enrollment share among volume-matched conditions near Phantom Limb Pain

Phantom Limb Pain lists 3 open slots (23% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Phantom Limb Pain on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Phantom Limb Pain is recruiting below its size-band peers.

    3 of 13 indexed trials (23.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Phantom Limb Pain research.

    Spaulding Rehabilitation Hospital accounts for 3 of 13 trials (23.1%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Most Phantom Limb Pain trials plan to enrol fewer than 100 people.

    Median target enrolment is 48 among the 13 trials that report a genuine target (sentinel values excluded). 8 of those (61.5%) plan for fewer than 100 participants.

  4. Phantom Limb Pain research is mostly interventional.

    13 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 41

Open and recent trials

13 total, page 1 of 1

RECRUITING NA 290 participants

Pragmatic Trial of Remote tDCS and Somatosensory Training for Phantom Limb Pain With Machine Learning to Predict Treatment Response

Spaulding Rehabilitation Hospital

NCT05188183

RECRUITING NA 110 participants

Surgical Treatments for Postamputation Pain

Prometei Pain Rehabilitation Center

NCT05009394

RECRUITING NA 36 participants

Home-based Rehabilitation Intervention for Phantom Limb Pain in Veterans With Lower Limb Amputations

VA Office of Research and Development

NCT06106984

ACTIVE NOT RECRUITING NA 607 participants

Electrical Nerve Block for Amputation Pain

Neuros Medical

NCT02221934

ACTIVE NOT RECRUITING NA 132 participants

Optimizing Rehabilitation for Phantom Limb Pain Using Mirror Therapy and Transcranial Direct Current Stimulation (tDCS)

Spaulding Rehabilitation Hospital

NCT02487966

ACTIVE NOT RECRUITING NA 48 participants

VR to Evaluate Phantom Limb Pain

Shirley Ryan AbilityLab

NCT05915065

ACTIVE NOT RECRUITING NA 4 participants

Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain

Prasad Shirvalkar, MD, PhD

NCT03029884

COMPLETED Phase 4 144 participants

Treating Phantom Limb Pain Using Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study

University of California, San Diego

NCT01824082

COMPLETED NA 57 participants

Controlled Study of Farabloc for Chronic Phantom Limb Pain Among Veteran Amputees

Southern California Institute for Research and Education

NCT00797849

COMPLETED NA 14 participants

Virtual Reality Treatment for Phantom Limb Pain

University of Pennsylvania

NCT03338842

COMPLETED NA 12 participants

Cryoanalgesia to Treat Phantom Limb Pain Following Above-Knee Amputation

University of California, San Diego

NCT06071715

COMPLETED 9 participants

Predicting Pain Response to Transcranial Direct Current Stimulation for Phantom Limb Pain in Limb Amputees

Spaulding Rehabilitation Hospital

NCT02627495

COMPLETED NA 8 participants

C-RFA of Residual Limb Neuroma

University of Utah

NCT04538417

Phase Distribution

PhaseTrial count
Phase 4 1

Named interventions

Most-linked intervention names on Phantom Limb Pain records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Distractor and Lower limb VR Device
1 trials
Cooled Radiofrequency Ablation Device
1 trials
Sham Limb Cover Device
1 trials
Farabloc Limb Cover Device
1 trials
transcranial Direct Current Stimulation (tDCS): (Soterix ©) Device
1 trials
SHAM cryoneurolysis Device
1 trials
ACTIVE cryoneurolysis Device
1 trials
Perineural infusion [continuous peripheral nerve block(s)] Drug
1 trials

US sites by state

Facility locations filed on Phantom Limb Pain trials. A trial with sites in several states counts in each.

Massachusetts 4 trials
California 4 trials
Illinois 3 trials
Ohio 2 trials
Minnesota 2 trials
Michigan 2 trials
Utah 1 trials
Texas 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Phantom Limb Pain page

13 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Phantom Limb Pain condition card totals 13 registered trials; most-linked intervention Distractor and Lower limb VR; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.