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Phantom Limb Pain clinical trials
Every US clinical trial registered for Phantom Limb Pain — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
13 US clinical trials · 3 currently recruiting
The research picture
Phantom Limb Pain has 13 registered US clinical trials, 3 of them open to new participants right now — about 23% of the total.
- 3
- recruiting participants now
- 23%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Spaulding Rehabilitation Hospital
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Pragmatic Trial of Remote tDCS and Somatosensory Training for Phantom Limb Pain With Machine Learning to Predict Treatment Response
Spaulding Rehabilitation Hospital
NCT05188183
Surgical Treatments for Postamputation Pain
Prometei Pain Rehabilitation Center
NCT05009394
Home-based Rehabilitation Intervention for Phantom Limb Pain in Veterans With Lower Limb Amputations
VA Office of Research and Development
NCT06106984
Electrical Nerve Block for Amputation Pain
Neuros Medical
NCT02221934
Optimizing Rehabilitation for Phantom Limb Pain Using Mirror Therapy and Transcranial Direct Current Stimulation (tDCS)
Spaulding Rehabilitation Hospital
NCT02487966
VR to Evaluate Phantom Limb Pain
Shirley Ryan AbilityLab
NCT05915065
Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain
Prasad Shirvalkar, MD, PhD
NCT03029884
Treating Phantom Limb Pain Using Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study
University of California, San Diego
NCT01824082
Controlled Study of Farabloc for Chronic Phantom Limb Pain Among Veteran Amputees
Southern California Institute for Research and Education
NCT00797849
Virtual Reality Treatment for Phantom Limb Pain
University of Pennsylvania
NCT03338842
Cryoanalgesia to Treat Phantom Limb Pain Following Above-Knee Amputation
University of California, San Diego
NCT06071715
Predicting Pain Response to Transcranial Direct Current Stimulation for Phantom Limb Pain in Limb Amputees
Spaulding Rehabilitation Hospital
NCT02627495
C-RFA of Residual Limb Neuroma
University of Utah
NCT04538417
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Phantom Limb Pain Trial Landscape
ClinicalTrials.gov lists 13 US studies indexed under Phantom Limb Pain, and 3 of those are currently open to recruitment — roughly 23% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Phantom Limb Pain shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 0 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Phantom Limb Pain is led by Spaulding Rehabilitation Hospital with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 13 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Phantom Limb Pain?
PlainTrial tracks 13 US clinical trials for Phantom Limb Pain, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Phantom Limb Pain?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.