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2026 data Public-data reference. official source

Peripheral Vascular Diseases

Open-data reference.

20 US clinical trials · 10 currently recruiting

Active & Recent Trials

RECRUITING 5,000 participants

Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature

Boston Scientific Corporation

NCT04674969

RECRUITING NA 720 participants

Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1

Virginia Commonwealth University

NCT04916327

RECRUITING NA 400 participants

Randomized Controlled Trial of Alert-Based Computerized Decision Support for Patients With Peripheral Artery Disease Not Prescribed Lipid-Lowering Therapy

Brigham and Women's Hospital

NCT06300450

RECRUITING NA 360 participants

Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 2

Virginia Commonwealth University

NCT04922762

RECRUITING NA 240 participants

Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 3

Virginia Commonwealth University

NCT04916340

RECRUITING Phase 3 210 participants

SMART Exercise for PAD

Northwestern University

NCT06032065

RECRUITING 175 participants

MRI Guided Management of Occlusive Peripheral Arterial Disease

The Methodist Hospital Research Institute

NCT06782100

RECRUITING Phase 2 34 participants

Fisetin to Reduce Senescence and Mobility Impairment in PAD

Northwestern University

NCT06399809

RECRUITING Early Phase 1 20 participants

Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease

University of Nebraska

NCT06319339

RECRUITING Phase 1 10 participants

The Effects of ATLAS Therapy on Nitric Oxide Bioavailability in Patients With Intermittent Claudication

Louis Messina

NCT04800692

ACTIVE NOT RECRUITING Phase 2 720 participants

Virtual Diabetes Group Visits Across Health Systems

University of Chicago

NCT06094491

COMPLETED 519 participants

Magnetic Resonance Imaging to Identify Characteristics of Plaque Build-Up in People With Peripheral Arterial Disease

Northwestern University

NCT00520312

COMPLETED NA 355 participants

Reducing Risk Factors in Peripheral Arterial Disease

Northwestern University

NCT00217919

COMPLETED NA 200 participants

GORE-TEX PROPATEN Vascular Graft Study

W.L.Gore & Associates

NCT00205790

COMPLETED NA 119 participants

GORE VIABAHN Endoprosthesis With Heparin Bioactive Surface in the Treatment of SFA Obstructive Disease (VIPER)

W.L.Gore & Associates

NCT00541307

COMPLETED NA 116 participants

Implementation of Telemedicine for Patient With Lower Extremity Wounds

University of California, Davis

NCT04440839

COMPLETED 100 participants

Distributed Registry

Stanford University

NCT03898570

COMPLETED Phase 2 100 participants

Alfimeprase for Thrombolysis in Acute Peripheral Arterial Occlusion

ARCA Biopharma

NCT00073554

COMPLETED Phase 4 30 participants

Peripheral Nerve Blocks for Above-the-knee Amputations

University of Florida

NCT03404180

COMPLETED Phase 1 9 participants

Natural Vascular Scaffold (NVS) Therapy for Treatment of Atherosclerotic Lesions (Activate I)

Alucent Biomedical

NCT04188262

Phase Distribution

PhaseTrial count
Early Phase 1 3
Phase 2 3
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Peripheral Vascular Diseases Trial Landscape

ClinicalTrials.gov lists 20 US studies indexed under Peripheral Vascular Diseases, and 10 of those are currently open to recruitment — roughly 50% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Peripheral Vascular Diseases shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Peripheral Vascular Diseases is led by Northwestern University with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 20 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Peripheral Vascular Diseases?

PlainTrial tracks 20 US clinical trials for Peripheral Vascular Diseases, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Peripheral Vascular Diseases?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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