Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04916327 · ClinicalTrials.gov registry record · NA
Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1
A NA study of Peripheral Vascular Diseases, sponsored by Virginia Commonwealth University.
- Recruiting
- Registry status
- NA
- Development phase
- 720
- Enrollment target
- 1
- Study location
NCT04916327: Recruiting NA study of Peripheral Vascular Diseases, sponsored by Virginia Commonwealth University.
NCT04916327 is a NA study of Peripheral Vascular Diseases that is actively recruiting participants, run by Virginia Commonwealth University. The registered enrollment target is 720 participants, above the 459-participant average among 19 other Peripheral Vascular Diseases trials with a reported enrollment target (57% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04916327, a NA study of Peripheral Vascular Diseases, is actively recruiting participants, sponsored by Virginia Commonwealth University.
- RECRUITING
- Registry status
- NA
- Development phase
- 720 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research study is to examine the role oxidants, substances produced in the blood that can damage blood vessel function, may play in blood vessel function in healthy individuals as well as individuals with mental health disorders (posttraumatic stress disorder (PTSD) and/or generalized anxiety disorder (GAD)).
Primary Outcome
Change in Brachial Artery Dilation from Baseline Values
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Placebo
- DIETARY_SUPPLEMENT Antioxidant
Study Locations (1)
Virginia
- Virginia Commonwealth University - Richmond
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 720 participants |
| Start Date | 2021-08-23 |
| Est. Completion | 2026-04 |
| Phase | NA |
What NCT04916327 shows while recruiting
NCT04916327 is an interventional study that assigns participants to a tested intervention. The registered 720 participants enrollment target is mid-sized for trials with a published cap, above the 459-participant average among 19 other Peripheral Vascular Diseases trials with a reported enrollment target (57% higher).
The record links to 1 condition, with Peripheral Vascular Diseases appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT04916327 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT04916327 about?
NCT04916327 is a clinical study titled "Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1". The purpose of this research study is to examine the role oxidants, substances produced in the blood that can damage blood vessel function, may play in blood vessel function in healthy individuals as well as individuals with mental health disorders (posttraumatic stress disorder (PTSD) and/or genera...
What is the current status of trial NCT04916327?
This trial is currently recruiting. It is a NA study. The enrollment target is 720 participants. The study started on 2021-08-23. Estimated completion is 2026-04.
What conditions does trial NCT04916327 study?
This clinical trial studies the following conditions: Peripheral Vascular Diseases.
What interventions are being tested in trial NCT04916327?
The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), Antioxidant (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT04916327?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04916327 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Peripheral Vascular Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04916327's enrollment target sits among peer trials
720 2nd of 19 higher than 17 of 19 other Peripheral Vascular Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Peripheral Vascular Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Randomized Controlled Trial of Alert-Based Computerized Decision Support for Patients With Peripheral Artery Disease Not Prescribed Lipid-Lowering Therapy
RECRUITING · NA
-
Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 2
RECRUITING · NA
-
Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 3
RECRUITING · NA
-
GORE-TEX PROPATEN Vascular Graft Study
COMPLETED · NA
-
GORE VIABAHN Endoprosthesis With Heparin Bioactive Surface in the Treatment of SFA Obstructive Disease (VIPER)
COMPLETED · NA
-
Implementation of Telemedicine for Patient With Lower Extremity Wounds
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT05047224 · 720 participants · NA
Addressing Disparities in Autism Spectrum Disorder Diagnosis Using a Direct-to-home Telemedicine Tool
- NCT05309395 · 720 participants · Phase 3
Food Prescriptions to Promote Affordable Diets
- NCT05466214 · 720 participants · NA
Systematic Efficacy Replication Study of Conjoint Behavioral Consultation in Elementary Schools
- NCT05768139 · 720 participants · Phase 1
First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI