Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Paroxysmal Atrial Fibrillation: later-stage trial registry
9 of 25 indexed Paroxysmal Atrial Fibrillation trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #652 of 28,707 conditions by registered trial count.
25 US clinical trials · 9 currently recruiting · #652 of 28,707 conditions by registered trial count
Paroxysmal Atrial Fibrillation: 25 US clinical trials tracked, 9 recruiting.
Paroxysmal Atrial Fibrillation is the subject of 25 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Boston Scientific Corporation, running 5 of these trials.
Enrollment posture brief
Registry condition paroxysmal-atrial-fibrillation
OPEN 9 | RECR 36% | LATE 4 | EARLY 1 | RANK #652 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Cannabis (36% recruiting · 25 trials)
Paroxysmal Atrial Fibrillation lists 9 open slots (36% of 25 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Paroxysmal Atrial Fibrillation on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Paroxysmal Atrial Fibrillation is recruiting below its size-band peers.
9 of 25 indexed trials (36%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
One sponsor concentrates Paroxysmal Atrial Fibrillation research.
Boston Scientific Corporation accounts for 5 of 25 trials (20%). 16 distinct sponsors appear on at least one study for this condition label.
-
Typical Paroxysmal Atrial Fibrillation enrolment sits around 228 participants.
Median target enrolment is 228 among the 25 trials that report a genuine target (sentinel values excluded). 4 of those (16%) plan for fewer than 100 participants.
-
Paroxysmal Atrial Fibrillation splits between interventional and observational designs.
15 interventional and 10 observational studies make up this index (60% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
25 total, page 1 of 1
Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation
Heart Rhythm Clinical and Research Solutions
NCT04088071
Pragmatic Evaluation of a Pentaspline Pulsed Field Ablation System to Treat Atrial Fibrillation and Related Arrhythmias
Vivek Reddy
NCT06765356
ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation vs Control in Redo Ablation Patients
Vivek Reddy
NCT05988411
The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.
Heart Rhythm Clinical and Research Solutions
NCT06324201
STOP AF First Post-Approval Study
Medtronic Cardiac Ablation Solutions
NCT05227053
POLARx Post Approval Study (POLARx PAS)
Boston Scientific Corporation
NCT06170606
Biomarker-Guided Optimization of Transcutaneous Vagal Stimulation for Atrial (BiG tVNS-AF)
University of Oklahoma
NCT05172765
Determinates of Atrial Tracking and Prevalence of Atrial Fibrillation in the Micra AV2 (DANCE AFIB)
Northwell Health
NCT07344961
EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation
Virginia Commonwealth University
NCT06212791
Safety and Effectiveness of the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal or Persistent Atrial Fibrillation
Kardium
NCT05462145
ADVENT Post Approval Study
Boston Scientific Corporation
NCT06431815
Treatment of PAF With the Synaptic System
Synaptic Medical Corporation
NCT05905835
Meditation and Education That is Nurse Delivered for Symptom Management in Paroxysmal Atrial Fibrillation (PAF)
Stanford University
NCT03834844
RHYTHMIA vs CARTO in Redo Ablation Procedures for Atrial Fibrillation
The Cleveland Clinic
NCT04835844
The FARAPULSE ADVENT PIVOTAL Trial PFA System vs SOC Ablation for Paroxysmal Atrial Fibrillation
Boston Scientific Corporation
NCT04612244
ADVENT Trial Long Term Outcomes Evaluating Atrial Fibrillation Progression Study
Boston Scientific Corporation
NCT06526546
TactiFlex Paroxysmal Atrial Fibrillation IDE Trial
Abbott Medical Devices
NCT04356040
Evaluation of VISITAG SURPOINT™ Module With External Processing Unit (EPU)
Biosense Webster
NCT03624881
Clinical Evaluation of the StablePoint Catheter and Force Sensing System for Paroxysmal Atrial Fibrillation
Boston Scientific Corporation
NCT04580914
Cryoballoon PVI With PWI Versus PVI Alone In Patients With PAF
Sacramento EP Research
NCT05296824
A Clinical Study of the Arctic Front Cryoablation Balloon for the Treatment of Paroxysmal Atrial Fibrillation
Medtronic Cardiac Rhythm and Heart Failure
NCT00523978
TactiCath® Contact Force Ablation Catheter Study for Atrial Fibrillation Post Approval Study
Abbott Medical Devices
NCT02310100
LSI (Lesion Index) Workflow Observational Study
Abbott Medical Devices
NCT03906461
A Comparison of Antiarrhythmic Drug Therapy and Radio Frequency Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation
Biosense Webster
NCT00540787
Clinical Study of the CardioFocus Endoscopic Ablation System - Adaptive Contact (EAS-AC) for the Treatment of Symptomatic Atrial Fibrillation
CardioFocus
NCT00971204
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
| Phase 3 | 1 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Paroxysmal Atrial Fibrillation records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Paroxysmal Atrial Fibrillation trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Paroxysmal Atrial Fibrillation page
25 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 9 Paroxysmal Atrial Fibrillation trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Boston Scientific Corporation sponsors the most Paroxysmal Atrial Fibrillation trials on record, review their full trial history before evaluating a specific study. See Boston Scientific Corporation's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Paroxysmal Atrial Fibrillation condition card totals 25 registered trials; most-linked intervention Cryoballoon ablation for the treatment of atrial fibrillation; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.