Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05988411 · ClinicalTrials.gov registry record · NA
ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation vs Control in Redo Ablation Patients
A NA study of Paroxysmal Atrial Fibrillation and Persistent Atrial Fibrillation, sponsored by Vivek Reddy.
- Recruiting
- Registry status
- NA
- Development phase
- 250
- Enrollment target
- 8
- Study locations
NCT05988411: Recruiting NA study of Paroxysmal Atrial Fibrillation and Persistent Atrial Fibrillation, sponsored by Vivek Reddy.
NCT05988411 is a NA study of Paroxysmal Atrial Fibrillation and Persistent Atrial Fibrillation that is actively recruiting participants, run by Vivek Reddy. The registered enrollment target is 250 participants, below the 849-participant average among 24 other Paroxysmal Atrial Fibrillation trials with a reported enrollment target (71% lower). The trial reports 8 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05988411, a NA study of Paroxysmal Atrial Fibrillation and Persistent Atrial Fibrillation, is actively recruiting participants, sponsored by Vivek Reddy.
- RECRUITING
- Registry status
- NA
- Development phase
- 250 participants
- Enrollment target
- 8
- Study locations
Study Summary
This is a Prospective, controlled, single-blind, randomized (2:1, Intervention:Control) clinical trial. The purpose of the study is to determine the role of adjunctive renal sympathetic denervation in the prevention of Atrial Fibrillation (AF) recurrence in patients with hypertension scheduled for a redo AF ablation procedure for paroxysmal or persistent AF. Patients will be randomized to either i) AF ablation (Control) or ii) AF ablation + renal sympathetic denervation (Intervention).
Primary Outcome
Freedom from atrial arrhythmias (AT/AF/AFL) recurrence ≥ 30 seconds off all antiarrhythmic drug uses (AADs) (after the 90-day blanking period).
Conditions Studied
Interventions
- DEVICE Renal Denervation
- DEVICE Catheter Ablation
Study Locations (8)
California
- UCSF - San Francisco
- Los Robles Medical Center - Thousand Oaks
Arkansas
- Arrhythmia Research Group - Jonesboro
Michigan
- Henry Ford Health System - Detroit
New York
- Mount Sinai Hospital - New York
South Carolina
- Trident Medical Center - Charleston
Texas
- Christus - Tyler
Virginia
- Virginia Commonwealth University - Richmond
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250 participants |
| Start Date | 2023-12-07 |
| Est. Completion | 2027-12 |
| Phase | NA |
What NCT05988411 shows while recruiting
NCT05988411 is an interventional study that assigns participants to a tested intervention. The registered 250 participants enrollment target is mid-sized for trials with a published cap, below the 849-participant average among 24 other Paroxysmal Atrial Fibrillation trials with a reported enrollment target (71% lower).
The record links to 2 conditions, with Paroxysmal Atrial Fibrillation appearing as the primary indexed condition, and to 2 interventions - of which Renal Denervation is the first listed.
NCT05988411 lists 8 locations in 7 states (California, Arkansas, Michigan).
Frequently Asked Questions
What is clinical trial NCT05988411 about?
NCT05988411 is a clinical study titled "ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation vs Control in Redo Ablation Patients". This is a Prospective, controlled, single-blind, randomized (2:1, Intervention:Control) clinical trial. The purpose of the study is to determine the role of adjunctive renal sympathetic denervation in the prevention of Atrial Fibrillation (AF) recurrence in patients with hypertension scheduled for a...
What is the current status of trial NCT05988411?
This trial is currently recruiting. It is a NA study. The enrollment target is 250 participants. The study started on 2023-12-07. Estimated completion is 2027-12.
What conditions does trial NCT05988411 study?
This clinical trial studies the following conditions: Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation.
What interventions are being tested in trial NCT05988411?
The interventions under investigation include: Renal Denervation (DEVICE), Catheter Ablation (DEVICE).
Who is sponsoring clinical trial NCT05988411?
This trial is sponsored by Vivek Reddy, which has 20 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05988411 being conducted?
This trial has 8 study locations across Arkansas, California, Michigan, New York, South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Paroxysmal Atrial Fibrillation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05988411's enrollment target sits among peer trials
250 10th of 24 higher than 14 of 24 other Paroxysmal Atrial Fibrillation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Paroxysmal Atrial Fibrillation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Biomarker-Guided Optimization of Transcutaneous Vagal Stimulation for Atrial (BiG tVNS-AF)
RECRUITING · NA
-
POLARx Post Approval Study (POLARx PAS)
RECRUITING · NA
-
Treatment of PAF With the Synaptic System
ACTIVE NOT RECRUITING · NA
-
Meditation and Education That is Nurse Delivered for Symptom Management in Paroxysmal Atrial Fibrillation (PAF)
ACTIVE NOT RECRUITING · NA
-
Safety and Effectiveness of the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal or Persistent Atrial Fibrillation
ACTIVE NOT RECRUITING · NA
-
TactiCath® Contact Force Ablation Catheter Study for Atrial Fibrillation Post Approval Study
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00483249 · 250 participants · NA
Endovascular Exclusion of Thoracoabdominal and/or Paravisceral Abdominal Aortic Aneurysm
- NCT00777712 · 250 participants
Mechanisms Underlying Impaired Diabetic Wound Healing
- NCT01451502 · 250 participants · NA
Infusion of Cell Populations From Unlicensed Umbilical Cord Blood Units
- NCT01771718 · 250 participants
Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI