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ClinicalTrials.gov 16 recruiting now official registry

Pancreatic Ductal Adenocarcinoma (PDAC) clinical trials

16 of 17 indexed Pancreatic Ductal Adenocarcinoma (PDAC) trials are currently recruiting.

17 US clinical trials · 16 currently recruiting

Pancreatic Ductal Adenocarcinoma (PDAC) is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 16 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is Revolution Medicines, running 3 of these trials.

The research picture

Pancreatic Ductal Adenocarcinoma (PDAC) has 17 registered US clinical trials, 16 of them open to new participants right now, about 94% of the total.

16
recruiting participants now
94%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
3
top sponsor: Revolution Medicines
Phase 112Phase 23Phase 31

Active & Recent Trials

17 total, page 1 of 1

RECRUITING 1,000 participants

A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer

City of Hope Medical Center

NCT07224750

RECRUITING Phase 1 754 participants

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

Revolution Medicines

NCT05379985

RECRUITING Phase 1 604 participants

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

Revolution Medicines

NCT06040541

RECRUITING Phase 1 574 participants

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

Revolution Medicines

NCT07349537

RECRUITING Phase 1 300 participants

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

Kura Oncology

NCT06026410

RECRUITING Phase 1 252 participants

A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

Bristol-Myers Squibb

NCT07223047

RECRUITING Phase 1 250 participants

Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)

EMD Serono Research & Development Institute

NCT06710132

RECRUITING Phase 1 200 participants

A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

Sutro Biopharma

NCT07227168

RECRUITING Phase 3 200 participants

Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)

SOFIE

NCT07217717

RECRUITING Phase 2 60 participants

EUS-RFA PANCARDINAL-1 Trial

The University of Texas Health Science Center, Houston

NCT04990609

RECRUITING Phase 1 46 participants

ProAgio in Pancreatic Ductal Adenocarcinoma (PDAC)

ProDa BioTech

NCT06182072

RECRUITING Phase 2 45 participants

Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer

UNC Lineberger Comprehensive Cancer Center

NCT03977233

RECRUITING Phase 2 39 participants

A Study of BT5528 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

BicycleTx Limited

NCT07450859

RECRUITING Phase 1 36 participants

Perioperative Fostamatinib With Gemcitabine and Nab-paclitaxel in Resectable Pancreatic Cancer

University of California, San Diego

NCT06639724

RECRUITING Phase 1 27 participants

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

Tanabe Pharma America

NCT06943521

RECRUITING Phase 1 10 participants

Intraperitoneal Paclitaxel With NALIRIFOX for Pancreatic Ductal Adenocarcinoma With Peritoneal Carcinomatosis

University of Colorado, Denver

NCT07030283

ACTIVE NOT RECRUITING Phase 1 350 participants

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

Genmab

NCT04083599

Phase Distribution

PhaseTrial count
Phase 1 12
Phase 2 3
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Pancreatic Ductal Adenocarcinoma (PDAC) Trial Landscape

17 indexed Pancreatic Ductal Adenocarcinoma (PDAC) studies · 16 recruiting (94%).

Phase mix: 1 late (III/IV) vs 15 early (I/II).

Top sponsor: Revolution Medicines (3 trials), 9 others listed. 17 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Pancreatic Ductal Adenocarcinoma (PDAC)?

PlainTrial tracks 17 US clinical trials for Pancreatic Ductal Adenocarcinoma (PDAC), of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Pancreatic Ductal Adenocarcinoma (PDAC)?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.