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ClinicalTrials.gov 16 recruiting now early-phase tilt small index

Pancreatic Ductal Adenocarcinoma (PDAC): early-phase trial registry

16 of 17 indexed Pancreatic Ductal Adenocarcinoma (PDAC) trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,004 of 28,707 conditions by registered trial count.

17 US clinical trials · 16 currently recruiting · #1,004 of 28,707 conditions by registered trial count

Pancreatic Ductal Adenocarcinoma (PDAC): 17 US clinical trials tracked, 16 recruiting.

Pancreatic Ductal Adenocarcinoma (PDAC) is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 16 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is Revolution Medicines, running 3 of these trials.

Enrollment posture brief

Registry condition pancreatic-ductal-adenocarcinoma-pdac

OPEN 16 | RECR 94% | LATE 1 | EARLY 15 | RANK #1004 | SPON 3

Nearest open-share peer: Substance Use Disorder (SUD) (94% recruiting · 16 trials)

Pancreatic Ductal Adenoc (th…94%Acute Myeloid Leukemia, in R70.6%Abdominal Aortic Aneurysm52.9%Acute Lymphoblastic Leukemia23.5%Actinic Keratosis11.8%
Open-enrollment share among volume-matched conditions near Pancreatic Ductal Adenocarcinoma (PDAC)

Pancreatic Ductal Adenocarcinoma (PDAC) lists 16 open slots (94% of 17 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Pancreatic Ductal Adenocarcinoma (PDAC) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Pancreatic Ductal Adenocarcinoma (PDAC) is recruiting above its size-band peers.

    16 of 17 indexed trials (94.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Pancreatic Ductal Adenocarcinoma (PDAC) research.

    Revolution Medicines accounts for 3 of 17 trials (17.6%). 15 distinct sponsors appear on at least one study for this condition label.

  3. Typical Pancreatic Ductal Adenocarcinoma (PDAC) enrolment sits around 200 participants.

    Median target enrolment is 200 among the 17 trials that report a genuine target (sentinel values excluded). 7 of those (41.2%) plan for fewer than 100 participants.

  4. Pancreatic Ductal Adenocarcinoma (PDAC) research is mostly interventional.

    16 interventional and 1 observational studies make up this index (94.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 112Phase 23Phase 31

Open and recent trials

17 total, page 1 of 1

RECRUITING 1,000 participants

A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer

City of Hope Medical Center

NCT07224750

RECRUITING Phase 1 754 participants

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

Revolution Medicines

NCT05379985

RECRUITING Phase 1 604 participants

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

Revolution Medicines

NCT06040541

RECRUITING Phase 1 574 participants

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

Revolution Medicines

NCT07349537

RECRUITING Phase 1 300 participants

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

Kura Oncology

NCT06026410

RECRUITING Phase 1 252 participants

A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

Bristol-Myers Squibb

NCT07223047

RECRUITING Phase 1 250 participants

Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)

EMD Serono Research & Development Institute

NCT06710132

RECRUITING Phase 1 200 participants

A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

Sutro Biopharma

NCT07227168

RECRUITING Phase 3 200 participants

Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)

SOFIE

NCT07217717

RECRUITING Phase 2 60 participants

EUS-RFA PANCARDINAL-1 Trial

The University of Texas Health Science Center, Houston

NCT04990609

RECRUITING Phase 1 46 participants

ProAgio in Pancreatic Ductal Adenocarcinoma (PDAC)

ProDa BioTech

NCT06182072

RECRUITING Phase 2 45 participants

Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer

UNC Lineberger Comprehensive Cancer Center

NCT03977233

RECRUITING Phase 2 39 participants

A Study of BT5528 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

BicycleTx Limited

NCT07450859

RECRUITING Phase 1 36 participants

Perioperative Fostamatinib With Gemcitabine and Nab-paclitaxel in Resectable Pancreatic Cancer

University of California, San Diego

NCT06639724

RECRUITING Phase 1 27 participants

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

Tanabe Pharma America

NCT06943521

RECRUITING Phase 1 10 participants

Intraperitoneal Paclitaxel With NALIRIFOX for Pancreatic Ductal Adenocarcinoma With Peritoneal Carcinomatosis

University of Colorado, Denver

NCT07030283

ACTIVE NOT RECRUITING Phase 1 350 participants

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

Genmab

NCT04083599

Phase Distribution

PhaseTrial count
Phase 1 12
Phase 2 3
Phase 3 1

Named interventions

Most-linked intervention names on Pancreatic Ductal Adenocarcinoma (PDAC) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Pembrolizumab Drug
3 trials
RMC-6236 Drug
2 trials
5-FU Drug
2 trials
GEN1042 Biological
1 trials
Endoscopic Ultrasound (EUS)-Guided Radiofrequency Ablation (RFA) Device
1 trials
BT5528 Drug
1 trials
Neoadjuvant Chemotherapy (NAC) Drug
1 trials
M9140 Drug
1 trials

US sites by state

Facility locations filed on Pancreatic Ductal Adenocarcinoma (PDAC) trials. A trial with sites in several states counts in each.

Texas 10 trials
California 9 trials
Florida 7 trials
Virginia 6 trials
Tennessee 5 trials
Massachusetts 5 trials
Ohio 4 trials
Maryland 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Pancreatic Ductal Adenocarcinoma (PDAC) page

17 registered trials, 16 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 16 Pancreatic Ductal Adenocarcinoma (PDAC) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Revolution Medicines sponsors the most Pancreatic Ductal Adenocarcinoma (PDAC) trials on record, review their full trial history before evaluating a specific study. See Revolution Medicines's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pancreatic Ductal Adenocarcinoma (PDAC) condition card totals 17 registered trials; most-linked intervention Pembrolizumab; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.