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ClinicalTrials.gov 15 recruiting now early-phase tilt small index

Substance Use Disorder (SUD): early-phase trial registry

15 of 16 indexed Substance Use Disorder (SUD) trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,060 of 28,707 conditions by registered trial count.

16 US clinical trials · 15 currently recruiting · #1,060 of 28,707 conditions by registered trial count

Substance Use Disorder (SUD): 16 US clinical trials tracked, 15 recruiting.

Substance Use Disorder (SUD) is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 15 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, San Francisco, running 3 of these trials.

Enrollment posture brief

Registry condition substance-use-disorder-sud

OPEN 15 | RECR 94% | LATE 1 | EARLY 2 | RANK #1060 | SPON 3

Nearest open-share peer: Pancreatic Ductal Adenocarcinoma (PDAC) (94% recruiting · 17 trials)

Substance Use Disorder (this)94%Adolescent62.5%Alcohol Intoxication56.3%AL Amyloidosis43.8%Allergy18.8%
Open-enrollment share among volume-matched conditions near Substance Use Disorder (SUD)

Substance Use Disorder (SUD) lists 15 open slots (94% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Substance Use Disorder (SUD) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Substance Use Disorder (SUD) is recruiting above its size-band peers.

    15 of 16 indexed trials (93.8%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Substance Use Disorder (SUD) research.

    University of California, San Francisco accounts for 3 of 16 trials (18.8%). 14 distinct sponsors appear on at least one study for this condition label.

  3. Typical Substance Use Disorder (SUD) enrolment sits around 100 participants.

    Median target enrolment is 100 among the 16 trials that report a genuine target (sentinel values excluded). 8 of those (50%) plan for fewer than 100 participants.

  4. Substance Use Disorder (SUD) research is mostly interventional.

    16 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 41

Open and recent trials

16 total, page 1 of 1

RECRUITING NA 1,270 participants

Pathways to Perinatal Mental Health Equity

University of Massachusetts, Worcester

NCT06790641

RECRUITING NA 640 participants

Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons

University of Arkansas

NCT06923423

RECRUITING NA 488 participants

Calls and Coordination for Transitions of Care at Re-entry

University of Wisconsin, Madison

NCT06794983

RECRUITING NA 318 participants

California MEPS Hub

University of California, Los Angeles

NCT07433985

RECRUITING NA 124 participants

The Trans-Led Care Study

Illinois Institute of Technology

NCT06880705

RECRUITING NA 120 participants

Transcranial Direct Current Stimulation (tDCS) for Treatment of Cocaine Use Disorder

Icahn School of Medicine at Mount Sinai

NCT07318480

RECRUITING Phase 4 100 participants

Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs

Massachusetts General Hospital

NCT07199335

RECRUITING NA 62 participants

Adolescent Stress and Substance Intervention Subsequent to Trauma

Rhode Island Hospital

NCT07197476

RECRUITING Phase 1 50 participants

Open-Label Psilocybin Study in Transdiagnostic Population

Yale University

NCT06442423

RECRUITING NA 50 participants

WORTH Paths Intervention

Fairleigh Dickinson University

NCT06889831

RECRUITING NA 50 participants

Wellness, Intervention Strategies and HIV Care

University of California, San Francisco

NCT07069374

RECRUITING NA 40 participants

Substance Use in Pregnant People - Optimizing Retention in Treatment

Washington University School of Medicine

NCT07104123

RECRUITING NA 36 participants

Contingency Management for Veteran Smokers Undergoing Major Elective Surgery

University of California, San Francisco

NCT06678672

RECRUITING Early Phase 1 20 participants

Evaluating Pain Control Strategies in Postpartum Patients on Opioid Use Disorder Medications.

Medical College of Wisconsin

NCT06617949

RECRUITING NA 6 participants

Individualized Adaptive Deep Brain Stimulation in Opioid Use Disorder

University of California, San Francisco

NCT07214467

ACTIVE NOT RECRUITING NA 360 participants

Addressing Barriers to Care for Substance Use Disorder Trial

Kaiser Permanente

NCT06729957

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 4 1

Named interventions

Most-linked intervention names on Substance Use Disorder (SUD) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Care Navigation Behavioral
1 trials
Movie Night Club - Attention and Time Matched Control Behavioral
1 trials
Wellness, Intervention Strategies and HIV Care (WISH) Behavioral
1 trials
Phone calls and texts - NCM Other
1 trials
Phone calls and texts Other
1 trials
In-person visit with NCM Other
1 trials
In-person visit with study team member Other
1 trials
PSI Peer Support Behavioral
1 trials

US sites by state

Facility locations filed on Substance Use Disorder (SUD) trials. A trial with sites in several states counts in each.

California 4 trials
Wisconsin 2 trials
Massachusetts 2 trials
Washington 1 trials
Rhode Island 1 trials
New York 1 trials
New Jersey 1 trials
North Dakota 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Substance Use Disorder (SUD) page

16 registered trials, 15 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Substance Use Disorder (SUD) condition card totals 16 registered trials; most-linked intervention Care Navigation; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.