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NCT04990609 · ClinicalTrials.gov registry record · Phase 2
EUS-RFA PANCARDINAL-1 Trial
A Phase 2 study of Pancreatic Ductal Adenocarcinoma (PDAC), sponsored by The University of Texas Health Science Center, Houston.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT04990609: Recruiting Phase 2 study of Pancreatic Ductal Adenocarcinoma (PDAC), sponsored by The University of Texas Health Science Center, Houston.
NCT04990609 is a Phase 2 study of Pancreatic Ductal Adenocarcinoma (PDAC) that is actively recruiting participants, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 60 participants, below the 293-participant average among 16 other Pancreatic Ductal Adenocarcinoma (PDAC) trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04990609, a Phase 2 study of Pancreatic Ductal Adenocarcinoma (PDAC), is actively recruiting participants, sponsored by The University of Texas Health Science Center, Houston.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The objectives of this study are to determine the feasibility, tolerability, and treatment effect of endoscopic ultrasound (EUS) radiofrequency ablation (RFA) plus standard-of-care neoadjuvant chemotherapy (NAC) in the treatment of pancreatic ductal adenocarcinoma (PDAC). Endoscopic ultrasound (EUS) radiofrequency ablation (RFA) and neoadjuvant chemotherapy (NAC) will be performed before tumor resection surgery, with the goal of shrinking a tumor or stopping the spread of cancer so that surgery might be less invasive and more effective.
Conditions Studied
Interventions
- DRUG Neoadjuvant Chemotherapy (NAC)
- DEVICE Endoscopic Ultrasound (EUS)-Guided Radiofrequency Ablation (RFA)
Study Locations (1)
Texas
- Memorial Hermann Hospital - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2021-08-13 |
| Est. Completion | 2028-05-30 |
| Phase | Phase 2 |
What NCT04990609 shows while recruiting
NCT04990609 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 293-participant average among 16 other Pancreatic Ductal Adenocarcinoma (PDAC) trials with a reported enrollment target (80% lower).
The record links to 1 condition, with Pancreatic Ductal Adenocarcinoma (PDAC) appearing as the primary indexed condition, and to 2 interventions - of which Neoadjuvant Chemotherapy (NAC) is the first listed.
NCT04990609 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT04990609 about?
NCT04990609 is a clinical study titled "EUS-RFA PANCARDINAL-1 Trial". The objectives of this study are to determine the feasibility, tolerability, and treatment effect of endoscopic ultrasound (EUS) radiofrequency ablation (RFA) plus standard-of-care neoadjuvant chemotherapy (NAC) in the treatment of pancreatic ductal adenocarcinoma (PDAC). Endoscopic ultrasound (EUS)...
What is the current status of trial NCT04990609?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2021-08-13. Estimated completion is 2028-05-30.
What conditions does trial NCT04990609 study?
This clinical trial studies the following conditions: Pancreatic Ductal Adenocarcinoma (PDAC).
What interventions are being tested in trial NCT04990609?
The interventions under investigation include: Neoadjuvant Chemotherapy (NAC) (DRUG), Endoscopic Ultrasound (EUS)-Guided Radiofrequency Ablation (RFA) (DEVICE).
Who is sponsoring clinical trial NCT04990609?
This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04990609 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pancreatic Ductal Adenocarcinoma (PDAC)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04990609's enrollment target sits among peer trials
60 11th of 16 higher than 6 of 16 other Pancreatic Ductal Adenocarcinoma (PDAC) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pancreatic Ductal Adenocarcinoma (PDAC) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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