Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Osteonecrosis: early-phase trial registry
3 of 8 indexed Osteonecrosis trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 3 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Osteonecrosis: 8 US clinical trials tracked, 3 recruiting.
Osteonecrosis is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Davis, running 2 of these trials.
Enrollment posture brief
Registry condition osteonecrosis
OPEN 3 | RECR 38% | LATE 1 | EARLY 2 | RANK #2176 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Acute-graft-versus-host Disease (38% recruiting · 8 trials)
Osteonecrosis lists 3 open slots (38% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Osteonecrosis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Osteonecrosis is recruiting below its size-band peers.
3 of 8 indexed trials (37.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Osteonecrosis research.
University of California, Davis accounts for 2 of 8 trials (25%). 7 distinct sponsors appear on at least one study for this condition label.
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Most Osteonecrosis trials plan to enrol fewer than 100 people.
Median target enrolment is 53 among the 8 trials that report a genuine target (sentinel values excluded). 6 of those (75%) plan for fewer than 100 participants.
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Osteonecrosis splits between interventional and observational designs.
5 interventional and 3 observational studies make up this index (62.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
Exactech Shoulder Post Market Clinical Follow-up Study
Exactech
NCT05603728
Alendronate for Osteonecrosis in Adults With Sickle Cell Disease
University of California, Davis
NCT06016634
Early Feasibility Study of Cartilage Defect Repair
Cytex Therapeutics
NCT06823089
Sickle Cell Disease (SCD) Bone Pain Study
University of California, Davis
NCT05283148
The Use of Genex in the Management of Early-Stage Osteonecrosis of the Femoral Head
The Cleveland Clinic
NCT05706909
Genetic Risk of Osteonecrosis of the Jaw (ONJ) in Patients With Metastatic Cancer
University of Michigan
NCT01325142
Randomized Controlled Trial of Hyperbaric Oxygen in Patients Who Have Taken Bisphosphonates
Duke University
NCT00462098
Imaging of Osteonecrosis With Ferumoxytol-Enhanced MRI
Stanford University
NCT02893293
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 1 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Osteonecrosis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Osteonecrosis trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Osteonecrosis page
8 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Osteonecrosis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of California, Davis sponsors the most Osteonecrosis trials on record, review their full trial history before evaluating a specific study. See University of California, Davis's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Osteonecrosis condition card totals 8 registered trials; most-linked intervention non-treated control group; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.