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2026 data Public-data reference. official source

Obese

Open-data reference.

28 US clinical trials · 8 currently recruiting

Active & Recent Trials

RECRUITING Phase 2 1,785 participants

Taxi ROADmAP (Realizing Optimization Around Diet And Physical Activity)

Memorial Sloan Kettering Cancer Center

NCT05770570

RECRUITING Phase 2 250 participants

Study to Evaluate HM15275 in Obese or Overweight Subjects Without Diabetes Mellitus

Hanmi Pharmaceutical Company Limited

NCT07205900

RECRUITING 120 participants

Exercise Response in Humans With Obesity

Mayo Clinic

NCT05857150

RECRUITING NA 100 participants

Trans-nasal Endoscopy for Bariatric Patients

Christopher C. Thompson, MD, MSc

NCT06200961

RECRUITING Phase 3 80 participants

Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome

University of Colorado, Denver

NCT05819853

RECRUITING Phase 2 50 participants

Aleniglipron Phase 2 in Type 2 Diabetes Mellitus

Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

NCT07400588

RECRUITING Phase 1 40 participants

A Single Ascending Dose Study of HM17321 in Healthy Adult Participants

Hanmi Pharmaceutical Company Limited

NCT07219589

RECRUITING Early Phase 1 30 participants

Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues

University of Chicago

NCT06171152

ACTIVE NOT RECRUITING NA 284 participants

The Expecting Study

Arkansas Children's Hospital Research Institute

NCT02125149

ACTIVE NOT RECRUITING NA 151 participants

Brain Fuel - Morning Nutrition and Cognitive Function

Arkansas Children's Hospital Research Institute

NCT03386396

ACTIVE NOT RECRUITING NA 100 participants

Project 1: Diet and Exercise Modulate the Sperm Epigenome in Men

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

NCT04175678

ACTIVE NOT RECRUITING 90 participants

Influence of Changes in Food Group Variety on Food Cravings, Energy Intake, and Weight Loss After Bariatric Surgery

The University of Tennessee, Knoxville

NCT01399177

ACTIVE NOT RECRUITING NA 44 participants

Olive Oil Polyphenols and Cardiovascular Health Biomarkers

University of California, Davis

NCT04149288

COMPLETED NA 668 participants

Financial Incentives for Weight Reduction Study

University of California, Los Angeles

NCT03157713

COMPLETED NA 301 participants

Self-Retaining Retractor in Obese Patients Undergoing Cesarean Section

St. Louis University

NCT01826604

COMPLETED NA 245 participants

Metabolism, Exercise and Nutrition at UCSD (MENU Study)

University of California, San Diego

NCT01424007

COMPLETED NA 241 participants

Families Improving Together (FIT) for Weight Loss

University of South Carolina

NCT01796067

COMPLETED NA 227 participants

UCSD Take Charge Study

University of California, San Diego

NCT01345500

COMPLETED NA 212 participants

mFit: The Mobile Fitness Project

University of California, Los Angeles

NCT01650337

COMPLETED 154 participants

Post-delivery Maternal-offspring Obesity and Metabolic Risk After a Prepregnancy Weight-loss Intervention

Kaiser Permanente

NCT06067126

COMPLETED Phase 2 141 participants

PDE5 Inhibition for Obesity-Related Cardiometabolic Dysfunction

Vanderbilt University Medical Center

NCT02819440

COMPLETED NA 100 participants

Prone Versus Left-sided Colonoscopy in Obese Patients

Dallas VA Medical Center

NCT01616602

COMPLETED NA 97 participants

Second Generation LMA Versus Endotracheal Tube in Obese Patients

University of Texas Southwestern Medical Center

NCT03748342

COMPLETED Phase 3 77 participants

Evaluating the Effects Two Diets Combined With Exercise in Persons With Abdominal Obesity (The SHAPE5 Study)

Johns Hopkins University

NCT00990457

COMPLETED NA 67 participants

Fit and Trim for Diabetes Prevention

University of California, San Francis

NCT02278939

COMPLETED NA 29 participants

Exercise and Weight Control

USDA Grand Forks Human Nutrition Research Center

NCT02152501

COMPLETED NA 16 participants

Mitochondrial Dysfunction in Diabetes

Mayo Clinic

NCT01724502

COMPLETED Phase 1 12 participants

In Vivo Leptin Signaling in Humans After Acute Leptin Administration

Beth Israel Deaconess Medical Center

NCT01275053

Reading the Obese Trial Landscape

ClinicalTrials.gov lists 28 US studies indexed under Obese, and 8 of those are currently open to recruitment — roughly 29% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Obese shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 7 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Obese is led by Arkansas Children's Hospital Research Institute with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 28 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Obese?

PlainTrial tracks 28 US clinical trials for Obese, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Obese?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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