Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01275053 · ClinicalTrials.gov registry record · Phase 1

In Vivo Leptin Signaling in Humans After Acute Leptin Administration

A Phase 1 study of Obese and Lean, sponsored by Beth Israel Deaconess Medical Center.

Completed
Registry status
Phase 1
Development phase
12
Enrollment target
1
Study location

NCT01275053 is a Phase 1 study of Obese and Lean that has completed, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 12 participants, below the 211-participant average among 27 other Obese trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01275053, a Phase 1 study of Obese and Lean, has completed, sponsored by Beth Israel Deaconess Medical Center.

COMPLETED
Registry status
Phase 1
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

The purpose of this research study is to help us to better understand how leptin regulates blood sugar levels. Leptin is a recently discovered hormone, which is made in fat cells. Leptin is secreted by fat and acts as a signal to the brain to decrease appetite and influences how the body regulates blood sugar levels. A synthetic form of leptin (A-100), an investigational drug and has not yet been approved by the Food and Drug Administration (FDA), will be administered to participants in this study. The expected duration of your participation is 3 study visits, which will be spread over 3-4 weeks. This study involves having fat and muscle biopsies after receiving leptin under local anesthesia in the General Clinical Research Center (GCRC), surgical unit, and/or Endocrinology exam room at the Beth Israel Deaconess Medical Center.

Interventions

  • DRUG leptin

Study Locations (1)

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2002-07
Est. Completion 2017-01
Phase Phase 1

What the Registry Record Tells You About NCT01275053

The ClinicalTrials.gov registry entry for NCT01275053 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 211-participant average among 27 other Obese trials with a reported enrollment target (94% lower). The listed sponsor is Beth Israel Deaconess Medical Center, which has 488 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Obese appearing as the primary indexed condition, and to 1 intervention - of which leptin is the first listed.

NCT01275053 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT01275053 about?

NCT01275053 is a clinical study titled "In Vivo Leptin Signaling in Humans After Acute Leptin Administration". The purpose of this research study is to help us to better understand how leptin regulates blood sugar levels. Leptin is a recently discovered hormone, which is made in fat cells. Leptin is secreted by fat and acts as a signal to the brain to decrease appetite and influences how the body regulates b...

What is the current status of trial NCT01275053?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2002-07. Estimated completion is 2017-01.

What conditions does trial NCT01275053 study?

This clinical trial studies the following conditions: Obese, Lean, Obese Diabetics.

What interventions are being tested in trial NCT01275053?

The interventions under investigation include: leptin (DRUG).

Who is sponsoring clinical trial NCT01275053?

This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01275053 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Obese

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.