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NCT00133367 · ClinicalTrials.gov registry record · Phase 2

Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus

A Phase 2 study of Multiple Myeloma and Non-Hodgkin's Lymphoma, sponsored by Massachusetts General Hospital.

Completed
Registry status
Phase 2
Development phase
32
Enrollment target
2
Study locations

NCT00133367: Completed Phase 2 study of Multiple Myeloma and Non-Hodgkin's Lymphoma, sponsored by Massachusetts General Hospital.

NCT00133367 is a Phase 2 study of Multiple Myeloma and Non-Hodgkin's Lymphoma that has completed, run by Massachusetts General Hospital. The registered enrollment target is 32 participants, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (94% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00133367, a Phase 2 study of Multiple Myeloma and Non-Hodgkin's Lymphoma, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
Phase 2
Development phase
32 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this study is to measure the effectiveness of 2 drugs, tacrolimus and sirolimus, in preventing graft versus host disease (GVHD) after treatment with chemotherapy followed by donor cord blood transplantation.

Interventions

  • DRUG Sirolimus
  • DRUG G-CSF
  • DRUG Thymoglobulin
  • DRUG Tacrolimus
  • DRUG Antithymocyte globulin

Study Locations (2)

Massachusetts

  • Massachusetts General Hospital - Boston
  • Dana-Farber Cancer Institute - Boston

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2005-08
Est. Completion 2011-11
Phase Phase 2
Massachusetts General Hospital

2,032 total trials

What the finished NCT00133367 record still lists

NCT00133367 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (94% lower).

The record links to 5 conditions, with Multiple Myeloma appearing as the primary indexed condition, and to 5 interventions - of which Sirolimus is the first listed.

NCT00133367 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT00133367 about?

NCT00133367 is a clinical study titled "Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus". The purpose of this study is to measure the effectiveness of 2 drugs, tacrolimus and sirolimus, in preventing graft versus host disease (GVHD) after treatment with chemotherapy followed by donor cord blood transplantation.

What is the current status of trial NCT00133367?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 32 participants. The study started on 2005-08. Estimated completion is 2011-11.

What conditions does trial NCT00133367 study?

This clinical trial studies the following conditions: Multiple Myeloma, Non-Hodgkin's Lymphoma, Hodgkin's Disease, Lymphoblastic Leukemia, Myelogenous Leukemia.

What interventions are being tested in trial NCT00133367?

The interventions under investigation include: Sirolimus (DRUG), G-CSF (DRUG), Thymoglobulin (DRUG), Tacrolimus (DRUG), Antithymocyte globulin (DRUG).

Who is sponsoring clinical trial NCT00133367?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00133367 being conducted?

This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Multiple Myeloma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00133367's enrollment target sits among peer trials

32 324th of 438 higher than 104 of 438 other Multiple Myeloma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Multiple Myeloma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00133367, the US trial registry maintained by the National Library of Medicine. NCT00133367 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.