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NCT00341952 · ClinicalTrials.gov registry record
Interdisciplinary Case-Control Study of Non-Hodgkin's Lymphoma
A clinical trial of Non-Hodgkin's Lymphoma, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- 2,378
- Enrollment target
- 4
- Study locations
NCT00341952: Completed study of Non-Hodgkin's Lymphoma, sponsored by National Cancer Institute (NCI).
NCT00341952 is a study of Non-Hodgkin's Lymphoma that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 2,378 participants, above the 184-participant average among 63 other Non-Hodgkin's Lymphoma trials with a reported enrollment target (1192% higher). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00341952, a study of Non-Hodgkin's Lymphoma, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- 2,378 participants
- Enrollment target
- 4
- Study locations
Study Summary
Non-Hodgkin's lymphoma (NHL) incidence rates have risen three percent per year in the U.S. for four decades. Mortality from NHL has risen 1.6 percent, compared with 0.2 percent for all cancers combined. This epidemic curve appears in both sexes and around the world, suggesting the possibility of an etiologic agent increasing in prevalence in the general environment. Recent research has identified several possible candidates including pesticides, other organochlorines, drinking water nitrates, and sunlight. There is an urgent need to evaluate whether these common exposures are contributing to the rapid rise in NHL, and to investigate other hypothesized risk factors such as viruses, medical conditions, hair dye use, and genetic factors. The purpose of this study is to examine the contribution to NHL risk of these important environmental, occupational, viral, medical, and personal exposures, and to pursue important leads emerging from on-going NHL research. This multidisciplinary, population-based case-control study will involve personal interviews to collect information on demographics, residential history, pesticide use, and occupational exposures; self-administered questionnaires to collect information on diet, family and medical history, and other exposures; tap water and carpet dust sampling to collect information on nitrate and pesticide exposures; and blood sampling for measurements of compounds in the serum, antibodies to viruses, and examination of genetic polymorphisms.
Primary Outcome
non-Hodgkin lymphoma cases versus controls
Conditions Studied
Study Locations (4)
California
- University of Southern California - Los Angeles
Iowa
- University of Iowa - Iowa City
Michigan
- Wayne State University Hutzel Hospital - Detroit
Washington
- University of Washington - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,378 participants |
| Start Date | 1998-04-15 |
| Est. Completion | 2007-04-17 |
What the finished NCT00341952 record still lists
NCT00341952 is an observational study that tracks outcomes without assigning an intervention. Its 2,378 participants enrollment target places it among the larger protocols in the corpus, above the 184-participant average among 63 other Non-Hodgkin's Lymphoma trials with a reported enrollment target (1192% higher).
The record links to 1 condition, with Non-Hodgkin's Lymphoma appearing as the primary indexed condition, and to 0 interventions.
NCT00341952 reports a single indexed study location in California, Iowa, Michigan.
Frequently Asked Questions
What is clinical trial NCT00341952 about?
NCT00341952 is a clinical study titled "Interdisciplinary Case-Control Study of Non-Hodgkin's Lymphoma". Non-Hodgkin's lymphoma (NHL) incidence rates have risen three percent per year in the U.S. for four decades. Mortality from NHL has risen 1.6 percent, compared with 0.2 percent for all cancers combined. This epidemic curve appears in both sexes and around the world, suggesting the possibility of an ...
What is the current status of trial NCT00341952?
This trial is currently completed. The enrollment target is 2,378 participants. The study started on 1998-04-15. Estimated completion is 2007-04-17.
What conditions does trial NCT00341952 study?
This clinical trial studies the following conditions: Non-Hodgkin's Lymphoma.
Who is sponsoring clinical trial NCT00341952?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00341952 being conducted?
This trial has 4 study locations across California, Iowa, Michigan, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00341952's enrollment target sits among peer trials
2,378 1st of 63 higher than 63 of 63 other Non-Hodgkin's Lymphoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Non-Hodgkin's Lymphoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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