Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Nicotine Use Disorder: early-phase trial registry
6 of 8 indexed Nicotine Use Disorder trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 6 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Nicotine Use Disorder: 8 US clinical trials tracked, 6 recruiting.
Nicotine Use Disorder is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Rutgers, The State University of New Jersey, running 2 of these trials.
Enrollment posture brief
Registry condition nicotine-use-disorder
OPEN 6 | RECR 75% | LATE 0 | EARLY 2 | RANK #2176 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Adolescent Idiopathic Scoliosis (75% recruiting · 8 trials)
Nicotine Use Disorder lists 6 open slots (75% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Nicotine Use Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Nicotine Use Disorder is recruiting above its size-band peers.
6 of 8 indexed trials (75%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Nicotine Use Disorder research.
Rutgers, The State University of New Jersey accounts for 2 of 8 trials (25%). 7 distinct sponsors appear on at least one study for this condition label.
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Most Nicotine Use Disorder trials plan to enrol fewer than 100 people.
Median target enrolment is 66 among the 8 trials that report a genuine target (sentinel values excluded). 5 of those (62.5%) plan for fewer than 100 participants.
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Nicotine Use Disorder research is mostly interventional.
8 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking
Washington State University
NCT05181891
Testing the Feasibility and Acceptability of Social Media and Digital Therapeutics to Decrease Vaping Behaviors
Washington University School of Medicine
NCT05994209
Temporal Interference Methods for Addiction Treatment
Indiana University
NCT07210268
Effects of Novel E-cigarette Constituents on Adults TCORS 3.0
Yale University
NCT05932745
Identify the Optimal TMS Pulse Protocol to Modulate Reward Activity
Rutgers, The State University of New Jersey
NCT06695884
Identify the Optimal TMS Target to Modulate Reward Activity
Rutgers, The State University of New Jersey
NCT05766254
Acute Effects of TCIG vs ECIG in PLWH
University of California, Los Angeles
NCT04568395
Families With Substance Use and Psychosis: A Pilot Study
Mclean Hospital
NCT04284813
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Nicotine Use Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Nicotine Use Disorder trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Nicotine Use Disorder page
8 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 6 Nicotine Use Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Rutgers, The State University of New Jersey sponsors the most Nicotine Use Disorder trials on record, review their full trial history before evaluating a specific study. See Rutgers, The State University of New Jersey's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Nicotine Use Disorder condition card totals 8 registered trials; most-linked intervention sham control; top US site state New Jersey. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.