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NCT05766254 · ClinicalTrials.gov registry record · NA

Identify the Optimal TMS Target to Modulate Reward Activity

A NA study of Nicotine Use Disorder, sponsored by Rutgers, The State University of New Jersey.

Recruiting
Registry status
NA
Development phase
36
Enrollment target
1
Study location

NCT05766254 is a NA study of Nicotine Use Disorder that is actively recruiting participants, run by Rutgers, The State University of New Jersey. The registered enrollment target is 36 participants, below the 98-participant average among 7 other Nicotine Use Disorder trials with a reported enrollment target (63% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05766254, a NA study of Nicotine Use Disorder, is actively recruiting participants, sponsored by Rutgers, The State University of New Jersey.

RECRUITING
Registry status
NA
Development phase
36 participants
Enrollment target
1
Study location

Study Summary

Our primary goal will be to identify the optimal prefrontal-cingulate target by systematically measuring the efficacy of various image-based targeting techniques to increase the reward positivity using the 10-Hz TMS protocol in dependent smokers. Our secondary objective will be to measure the targets' effectiveness to increase decision-making capacity using the probabilistic selection task (PST). Our third objective will be to specifically assess whether the TMS targets has a differential impact on state levels of craving relative to baseline (Tobacco Craving Questionnaire \[TCQ\]. We plan to accomplish these three objectives using a randomized, controlled experiment involving 3 sessions.

Conditions Studied

Interventions

  • DEVICE Active 10-Hz TMS to the DLPFC
  • DEVICE Sham TMS-DLPFC

Study Locations (1)

New Jersey

  • Rutgers University - Newark - Newark

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2023-03-24
Est. Completion 2026-09
Phase NA

What the Registry Record Tells You About NCT05766254

The ClinicalTrials.gov registry entry for NCT05766254 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 98-participant average among 7 other Nicotine Use Disorder trials with a reported enrollment target (63% lower). The listed sponsor is Rutgers, The State University of New Jersey, which has 413 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Nicotine Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which Active 10-Hz TMS to the DLPFC is the first listed.

NCT05766254 reports 1 study location spanning 1 distinct geographic area - top geographies include New Jersey.

Frequently Asked Questions

What is clinical trial NCT05766254 about?

NCT05766254 is a clinical study titled "Identify the Optimal TMS Target to Modulate Reward Activity". Our primary goal will be to identify the optimal prefrontal-cingulate target by systematically measuring the efficacy of various image-based targeting techniques to increase the reward positivity using the 10-Hz TMS protocol in dependent smokers. Our secondary objective will be to measure the target...

What is the current status of trial NCT05766254?

This trial is currently recruiting. It is a NA study. The enrollment target is 36 participants. The study started on 2023-03-24. Estimated completion is 2026-09.

What conditions does trial NCT05766254 study?

This clinical trial studies the following conditions: Nicotine Use Disorder.

What interventions are being tested in trial NCT05766254?

The interventions under investigation include: Active 10-Hz TMS to the DLPFC (DEVICE), Sham TMS-DLPFC (DEVICE).

Who is sponsoring clinical trial NCT05766254?

This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05766254 being conducted?

This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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