Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Netherton Syndrome: early-phase trial registry
4 of 7 indexed Netherton Syndrome trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,497 of 28,707 conditions by registered trial count.
7 US clinical trials · 4 currently recruiting · #2,497 of 28,707 conditions by registered trial count
Netherton Syndrome: 7 US clinical trials tracked, 4 recruiting.
Netherton Syndrome is the subject of 7 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is Quoin Pharmaceuticals, running 3 of these trials.
Enrollment posture brief
Registry condition netherton-syndrome
OPEN 4 | RECR 57% | LATE 0 | EARLY 7 | RANK #2497 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Adverse Childhood Experiences (57% recruiting · 14 trials)
Netherton Syndrome lists 4 open slots (57% of 7 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Netherton Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Netherton Syndrome is recruiting above its size-band peers.
4 of 7 indexed trials (57.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Netherton Syndrome research.
Quoin Pharmaceuticals accounts for 3 of 7 trials (42.9%). 5 distinct sponsors appear on at least one study for this condition label.
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Most Netherton Syndrome trials plan to enrol fewer than 100 people.
Median target enrolment is 20 among the 7 trials that report a genuine target (sentinel values excluded). 7 of those (100%) plan for fewer than 100 participants.
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Netherton Syndrome research is mostly interventional.
7 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
7 total, page 1 of 1
A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725
BioCryst Pharmaceuticals
NCT06539507
Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome
Quoin Pharmaceuticals
NCT05789056
Evaluation of Topical ATR12-351 in Adults With Netherton Syndrome
Azitra
NCT06137157
Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome
Quoin Pharmaceuticals
NCT06953466
Safety, Tolerability and Efficacy of QRX003 Lotion in Subjects With Netherton Syndrome
Quoin Pharmaceuticals
NCT05521438
The Efficacy and Safety of Secukinumab in Patients With Ichthyoses
Northwestern University
NCT03041038
Safety Study of Elidel (Pimecrolimus) 1% Cream to Treat Netherton Syndrome
Children's Hospital of Philadelphia
NCT00208026
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Netherton Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Netherton Syndrome trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Netherton Syndrome page
7 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 Netherton Syndrome trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Quoin Pharmaceuticals sponsors the most Netherton Syndrome trials on record, review their full trial history before evaluating a specific study. See Quoin Pharmaceuticals's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Netherton Syndrome condition card totals 7 registered trials; most-linked intervention QRX003, 4% Lotion; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.