Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Adverse Childhood Experiences: early-phase trial registry
8 of 14 indexed Adverse Childhood Experiences trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,230 of 28,707 conditions by registered trial count.
14 US clinical trials · 8 currently recruiting · #1,230 of 28,707 conditions by registered trial count
Adverse Childhood Experiences: 14 US clinical trials tracked, 8 recruiting.
Adverse Childhood Experiences is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Nathaniel Jenkins, running 2 of these trials.
Enrollment posture brief
Registry condition adverse-childhood-experiences
OPEN 8 | RECR 57% | LATE 0 | EARLY 1 | RANK #1230 | SPON 2
Volume-matched condition peers
Nearest open-share peer: ACL (57% recruiting · 7 trials)
Adverse Childhood Experiences lists 8 open slots (57% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Adverse Childhood Experiences on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Adverse Childhood Experiences is recruiting above its size-band peers.
8 of 14 indexed trials (57.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Adverse Childhood Experiences trials is spread across many organizations.
Nathaniel Jenkins accounts for 2 of 14 trials (14.3%). 13 distinct sponsors appear on at least one study for this condition label.
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Typical Adverse Childhood Experiences enrolment sits around 120 participants.
Median target enrolment is 120 among the 14 trials that report a genuine target (sentinel values excluded). 7 of those (50%) plan for fewer than 100 participants.
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Adverse Childhood Experiences research is mostly interventional.
11 interventional and 3 observational studies make up this index (78.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
14 total, page 1 of 1
School Violence Exposure as an Adverse Childhood Experience
Teachers College, Columbia University
NCT06153316
Evaluating an Adverse Childhood Experience-Targeting Advocate Model of a Substance Use Prevention Program
RTI International
NCT06236100
Building Resilient Families
Loma Linda University
NCT05388864
The THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments
University of California, Irvine
NCT06821035
Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking
Duke University
NCT05665465
The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies
Nathaniel Jenkins
NCT06454344
ACEs, SIRT1, and Premature Vascular Aging in Humans
Nathaniel Jenkins
NCT07073352
Early Life Exposures Among Children With Sickle Cell Disease
University of Alabama at Birmingham
NCT05377372
Assessing the Gut Microbiome and Its Association With Pediatric Stress and Cognition
Nova Southeastern University
NCT06269614
Playing Playfully to Overcome Adversity
Sacred Heart University
NCT06985017
The Impact of an Adapted Version of the Strengthening Families Program on IPV Among Caregivers and ACEs Among Children
University of Nebraska Lincoln
NCT05129501
ACE, Resilience, and Substance Use Disorder: Maternal and Baby Outcomes in the First Year of Life
The Cooper Health System
NCT05731557
Brief Intervention for Chronic Pain and History of Stressful Experiences
Brigham and Women's Hospital
NCT06983327
Journey of Hope in Appalachia: Supporting Resilience in the Region's Youth
Gia Mudd
NCT04096937
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Adverse Childhood Experiences records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Adverse Childhood Experiences trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Adverse Childhood Experiences page
14 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 8 Adverse Childhood Experiences trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Nathaniel Jenkins sponsors the most Adverse Childhood Experiences trials on record, review their full trial history before evaluating a specific study. See Nathaniel Jenkins's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Adverse Childhood Experiences condition card totals 14 registered trials; most-linked intervention Trauma Focused Emotional Awareness and Expression Therapy (EAET); top US site state New Jersey. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.