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ClinicalTrials.gov 10 recruiting now early-phase tilt small index

Nephrolithiasis: early-phase trial registry

10 of 17 indexed Nephrolithiasis trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,004 of 28,707 conditions by registered trial count.

17 US clinical trials · 10 currently recruiting · #1,004 of 28,707 conditions by registered trial count

Nephrolithiasis: 17 US clinical trials tracked, 10 recruiting.

Nephrolithiasis is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is University of Alabama at Birmingham, running 3 of these trials.

Enrollment posture brief

Registry condition nephrolithiasis

OPEN 10 | RECR 59% | LATE 0 | EARLY 2 | RANK #1004 | SPON 3

Nearest open-share peer: HPV Positive Oropharyngeal Squamous Cell Carcinoma (59% recruiting · 17 trials)

Acute Myeloid Leukemia, in R70.6%Nephrolithiasis (this)59%Abdominal Aortic Aneurysm52.9%Acute Lymphoblastic Leukemia23.5%Actinic Keratosis11.8%
Open-enrollment share among volume-matched conditions near Nephrolithiasis

Nephrolithiasis lists 10 open slots (59% of 17 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Nephrolithiasis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Nephrolithiasis is recruiting above its size-band peers.

    10 of 17 indexed trials (58.8%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Nephrolithiasis research.

    University of Alabama at Birmingham accounts for 3 of 17 trials (17.6%). 14 distinct sponsors appear on at least one study for this condition label.

  3. Typical Nephrolithiasis enrolment sits around 85 participants.

    Median target enrolment is 85 among the 17 trials that report a genuine target (sentinel values excluded). 10 of those (58.8%) plan for fewer than 100 participants.

  4. Nephrolithiasis research is mostly interventional.

    15 interventional and 2 observational studies make up this index (88.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 21

Open and recent trials

17 total, page 1 of 1

RECRUITING 150 participants

Serum Endotoxin Assay to Predict the Development of Postoperative Infectious Complications and Systemic Inflammatory Response Following Percutaneous Nephrolithotomy.

University of Miami

NCT04669886

RECRUITING NA 150 participants

ClearPetra™ Vacuum-assisted Ureteral Access Sheath vs Traditional Approach

University of Kansas Medical Center

NCT06547632

RECRUITING NA 126 participants

Methocarbamol vs Oxybutynin for Management of Pain and Discomfort S/P Ureteroscopy Procedure

Northwestern University

NCT05100017

RECRUITING Phase 2 116 participants

Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain

University of Chicago

NCT06635889

RECRUITING NA 80 participants

Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease

University of Alabama at Birmingham

NCT06989320

RECRUITING NA 80 participants

Gut Oxalate Absorption in Calcium Oxalate Stone Disease

University of Alabama at Birmingham

NCT06331546

RECRUITING NA 80 participants

Evaluation of the LithoVue Elite Ureteroscope With Intra-Renal Pressure Monitoring Technology: Examination of Surgeon Behavior and Post-operative Outcomes

University of Kansas Medical Center

NCT06576661

RECRUITING NA 50 participants

Thulium Fiber Laser (TFL) vs Thulio Pulsed Thulium:YAG (p-Tm:YAG)

University of California, San Diego

NCT06721975

RECRUITING NA 40 participants

O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease

University of Alabama at Birmingham

NCT06330246

RECRUITING NA 15 participants

Evaluation of Genetic Abnormalities Amongst Calcium Phosphate Stone Formers

Ryan L Steinberg

NCT06974357

ACTIVE NOT RECRUITING NA 370 participants

Ultrasound Imaging of Kidney Stones and Lithotripsy

University of Washington

NCT02214836

ACTIVE NOT RECRUITING NA 116 participants

SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD)

SonoMotion

NCT05701098

COMPLETED NA 388 participants

Ultrasound First Clinical Decision Support for Suspected Nephrolithiasis

University of California, San Francisco

NCT03461536

COMPLETED 90 participants

Brushite Kidney Stones: A Registry and Database of Clinical and Laboratory Findings

Indiana Kidney Stone Institute

NCT00169663

COMPLETED NA 85 participants

Hidrate Me Smart Water Bottle Use in Patient With Nephrolithiasis

University of Minnesota

NCT02938884

COMPLETED Phase 1 40 participants

Use of Oral Probiotics to Reduce Urinary Oxalate Excretion

Mayo Clinic

NCT00587041

COMPLETED NA 12 participants

Effect of Diet Orange Soda on Urinary Lithogenicity

VA New York Harbor Healthcare System

NCT01330940

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1

Named interventions

Most-linked intervention names on Nephrolithiasis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

HidrateSpark Water Bottle Device
1 trials
Ultrasound-first Clinical Decision Support tool Behavioral
1 trials
Agri-King Synbiotic (AKSB) Dietary supplement
1 trials
Oxadrop Dietary supplement
1 trials
Orange soda Dietary supplement
1 trials
Verasonics Data Acquisition System (VDAS) Device
1 trials
ClearPetra Ureteral access sheath Device
1 trials
Normal saline Other
1 trials

US sites by state

Facility locations filed on Nephrolithiasis trials. A trial with sites in several states counts in each.

Illinois 4 trials
Texas 3 trials
California 3 trials
Alabama 3 trials
Washington 2 trials
Minnesota 2 trials
Kansas 2 trials
Indiana 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Nephrolithiasis page

17 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Nephrolithiasis condition card totals 17 registered trials; most-linked intervention HidrateSpark Water Bottle; top US site state Illinois. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.