Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Nephrolithiasis

Open-data reference.

17 US clinical trials · 10 currently recruiting

Active & Recent Trials

RECRUITING 150 participants

Serum Endotoxin Assay to Predict the Development of Postoperative Infectious Complications and Systemic Inflammatory Response Following Percutaneous Nephrolithotomy.

University of Miami

NCT04669886

RECRUITING NA 150 participants

ClearPetra™ Vacuum-assisted Ureteral Access Sheath vs Traditional Approach

University of Kansas Medical Center

NCT06547632

RECRUITING NA 126 participants

Methocarbamol vs Oxybutynin for Management of Pain and Discomfort S/P Ureteroscopy Procedure

Northwestern University

NCT05100017

RECRUITING Phase 2 116 participants

Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain

University of Chicago

NCT06635889

RECRUITING NA 80 participants

Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease

University of Alabama at Birmingham

NCT06989320

RECRUITING NA 80 participants

Gut Oxalate Absorption in Calcium Oxalate Stone Disease

University of Alabama at Birmingham

NCT06331546

RECRUITING NA 80 participants

Evaluation of the LithoVue Elite Ureteroscope With Intra-Renal Pressure Monitoring Technology: Examination of Surgeon Behavior and Post-operative Outcomes

University of Kansas Medical Center

NCT06576661

RECRUITING NA 50 participants

Thulium Fiber Laser (TFL) vs Thulio Pulsed Thulium:YAG (p-Tm:YAG)

University of California, San Diego

NCT06721975

RECRUITING NA 40 participants

O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease

University of Alabama at Birmingham

NCT06330246

RECRUITING NA 15 participants

Evaluation of Genetic Abnormalities Amongst Calcium Phosphate Stone Formers

Ryan L Steinberg

NCT06974357

ACTIVE NOT RECRUITING NA 370 participants

Ultrasound Imaging of Kidney Stones and Lithotripsy

University of Washington

NCT02214836

ACTIVE NOT RECRUITING NA 116 participants

SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD)

SonoMotion

NCT05701098

COMPLETED NA 388 participants

Ultrasound First Clinical Decision Support for Suspected Nephrolithiasis

University of California, San Francis

NCT03461536

COMPLETED 90 participants

Brushite Kidney Stones: A Registry and Database of Clinical and Laboratory Findings

Indiana Kidney Stone Institute

NCT00169663

COMPLETED NA 85 participants

Hidrate Me Smart Water Bottle Use in Patient With Nephrolithiasis

University of Minnesota

NCT02938884

COMPLETED Phase 1 40 participants

Use of Oral Probiotics to Reduce Urinary Oxalate Excretion

Mayo Clinic

NCT00587041

COMPLETED NA 12 participants

Effect of Diet Orange Soda on Urinary Lithogenicity

VA New York Harbor Healthcare System

NCT01330940

Phase Distribution

PhaseTrial count
Early Phase 1 1
Phase 2 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Nephrolithiasis Trial Landscape

ClinicalTrials.gov lists 17 US studies indexed under Nephrolithiasis, and 10 of those are currently open to recruitment — roughly 59% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Nephrolithiasis shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Nephrolithiasis is led by University of Alabama at Birmingham with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 17 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Nephrolithiasis?

PlainTrial tracks 17 US clinical trials for Nephrolithiasis, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Nephrolithiasis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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