Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT06974357 · ClinicalTrials.gov registry record · NA

Evaluation of Genetic Abnormalities Amongst Calcium Phosphate Stone Formers

A NA study of Nephrolithiasis, sponsored by Ryan L Steinberg.

Recruiting
Registry status
NA
Development phase
15
Enrollment target
1
Study location

NCT06974357 is a NA study of Nephrolithiasis that is actively recruiting participants, run by Ryan L Steinberg. The registered enrollment target is 15 participants, below the 123-participant average among 16 other Nephrolithiasis trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT06974357, a NA study of Nephrolithiasis, is actively recruiting participants, sponsored by Ryan L Steinberg.

RECRUITING
Registry status
NA
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

Kidney stones continue to affect more and more people in the United States with the most recent estimate being 1 in 9 people will develop a stone in their life. While family history is a known risk factor for stone disease, it remains unclear whether this is related to learned dietary habits or a truly inheritable genetic condition. Known inheritable genetic conditions linked to stone formation are uncommon, and thus, routine genetic testing is not currently recommended by any major urologic organizations. Patients who form calcium phosphate predominant stones, a less common type of stone composition, tend to have alkaline urine pH which suggests that the kidneys are unable to rid the body of acid. Management of such patients for stone prevention can be difficult. The Iowa Institute for Human Genomics is one of only a handful of commercial labs which offers genetic testing for stone disease. The aim of this study is to assess the rate of genetic abnormalities amongst calcium phosphate predominant stone formers with alkaline urine. To this end, the investigators plan to enroll calcium phosphate predominant stone forming patients with alkaline urine on 24 hour urine collection who obtain their health care at UIHC to undergo free genetic testing via blood draw to assess for genetic abnormalities. The investigators will also collect information already available in the subject's chart to assess for other patterns between blood and urine tests and any genetic variants.

Conditions Studied

Nephrolithiasis

Interventions

  • DIAGNOSTIC_TEST Genetic testing

Study Locations (1)

Iowa

  • University of Iowa - Iowa City

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2025-03-15
Est. Completion 2027-03-01
Phase NA

Sponsor

Ryan L Steinberg

1 total trials

Interested in This Trial?

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06974357

The ClinicalTrials.gov registry entry for NCT06974357 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 123-participant average among 16 other Nephrolithiasis trials with a reported enrollment target (88% lower). The listed sponsor is Ryan L Steinberg, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Nephrolithiasis appearing as the primary indexed condition, and to 1 intervention - of which Genetic testing is the first listed.

NCT06974357 reports 1 study location spanning 1 distinct geographic area - top geographies include Iowa.

Frequently Asked Questions

What is clinical trial NCT06974357 about?

NCT06974357 is a clinical study titled "Evaluation of Genetic Abnormalities Amongst Calcium Phosphate Stone Formers". Kidney stones continue to affect more and more people in the United States with the most recent estimate being 1 in 9 people will develop a stone in their life. While family history is a known risk factor for stone disease, it remains unclear whether this is related to learned dietary habits or a tr...

What is the current status of trial NCT06974357?

This trial is currently recruiting. It is a NA study. The enrollment target is 15 participants. The study started on 2025-03-15. Estimated completion is 2027-03-01.

What conditions does trial NCT06974357 study?

This clinical trial studies the following conditions: Nephrolithiasis.

What interventions are being tested in trial NCT06974357?

The interventions under investigation include: Genetic testing (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT06974357?

This trial is sponsored by Ryan L Steinberg, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06974357 being conducted?

This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Nephrolithiasis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Explore more on PlainTrial

Nephrolithiasis

All registered trials for this condition

Iowa

All trials with a study site in Iowa

Recruiting now

Find trials open to new participants near you

Rankings

Top sponsors, conditions, and phases

Read our methodology - how this data is sourced, computed, and verified.

Related

Browse all → | Rankings →
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.