Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Narcolepsy: full-pipeline trial registry
4 of 13 indexed Narcolepsy trials are currently recruiting.
Corpus placement: #1,315 of 28,707 conditions by registered trial count.
13 US clinical trials · 4 currently recruiting · #1,315 of 28,707 conditions by registered trial count
Narcolepsy: 13 US clinical trials tracked, 4 recruiting.
Narcolepsy is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Jazz Pharmaceuticals, running 5 of these trials.
Enrollment posture brief
Registry condition narcolepsy
OPEN 4 | RECR 31% | LATE 3 | EARLY 3 | RANK #1315 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Acute Decompensated Heart Failure (31% recruiting · 13 trials)
Narcolepsy lists 4 open slots (31% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Narcolepsy on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Narcolepsy is recruiting below its size-band peers.
4 of 13 indexed trials (30.8%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Narcolepsy research.
Jazz Pharmaceuticals accounts for 5 of 13 trials (38.5%). 7 distinct sponsors appear on at least one study for this condition label.
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Typical Narcolepsy enrolment sits around 140 participants.
Median target enrolment is 140 among the 13 trials that report a genuine target (sentinel values excluded). 6 of those (46.2%) plan for fewer than 100 participants.
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Narcolepsy splits between interventional and observational designs.
8 interventional and 5 observational studies make up this index (61.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
13 total, page 1 of 1
SUNOSI® (Solriamfetol) Pregnancy Registry
Axsome Therapeutics
NCT06413420
WAKIX® (Pitolisant) Pregnancy Registry
Harmony Biosciences Management
NCT05536011
Child and Adolescent Registry for Participants With Narcolepsy
Jazz Pharmaceuticals
NCT04899947
A Study to Investigate Efficacy, Safety, Tolerability, and Pharmacokinetics of JZP441 Compared With Placebo in Participants With Narcolepsy Type 1
Jazz Pharmaceuticals
NCT06961266
Study to Assess Patient Reported Outcomes With Armodafinil Treatment for Excessive Sleepiness in Adults With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome
Cephalon
NCT00228566
Development and Validation of Pediatric Narcolepsy Patient Reported Outcomes Scale
Boston Children's Hospital
NCT05373979
A Switch Study From High-Sodium Oxybate to XYWAV to Evaluate Changes in Blood Pressure in Participants With Narcolepsy
Jazz Pharmaceuticals
NCT05869773
Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy
Cephalon
NCT00107796
A Study of the Safety and Effectiveness of ADX-N05 for Excessive Daytime Sleepiness in Subjects With Narcolepsy
Jazz Pharmaceuticals
NCT01681121
Observational Study of LUMRYZ in Narcolepsy
Avadel
NCT06792708
Psychosocial Adjunctive Treatment for Hypersomnia (PATH)
Northwestern University
NCT03904238
A Study of the Safety and Effectiveness of ADX-N05 in the Treatment of Excessive Daytime Sleepiness
Jazz Pharmaceuticals
NCT01485770
Narcolepsy Nightmare Study
Northwestern University
NCT05709873
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 3 | 2 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Narcolepsy records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Narcolepsy trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Narcolepsy page
13 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 Narcolepsy trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Jazz Pharmaceuticals sponsors the most Narcolepsy trials on record, review their full trial history before evaluating a specific study. See Jazz Pharmaceuticals's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Narcolepsy condition card totals 13 registered trials; most-linked intervention ADX-N05; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.