Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 6 recruiting now early-phase tilt small index

Myeloproliferative Neoplasms: early-phase trial registry

6 of 9 indexed Myeloproliferative Neoplasms trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,916 of 28,707 conditions by registered trial count.

9 US clinical trials · 6 currently recruiting · #1,916 of 28,707 conditions by registered trial count

Myeloproliferative Neoplasms: 9 US clinical trials tracked, 6 recruiting.

Myeloproliferative Neoplasms is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Incyte Corporation, running 4 of these trials.

Enrollment posture brief

Registry condition myeloproliferative-neoplasms

OPEN 6 | RECR 67% | LATE 0 | EARLY 9 | RANK #1916 | SPON 4

Nearest open-share peer: Acute Hypoxemic Respiratory Failure (67% recruiting · 6 trials)

Myeloproliferative Neopl (th…67%Acute Lymphoblastic Leukemia55.6%Acute Respiratory Distress S55.6%Acute Otitis Media22.2%Acute Heart Failure11.1%
Open-enrollment share among volume-matched conditions near Myeloproliferative Neoplasms

Myeloproliferative Neoplasms lists 6 open slots (67% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Myeloproliferative Neoplasms on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Myeloproliferative Neoplasms is recruiting above its size-band peers.

    6 of 9 indexed trials (66.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Myeloproliferative Neoplasms research.

    Incyte Corporation accounts for 4 of 9 trials (44.4%). 6 distinct sponsors appear on at least one study for this condition label.

  3. Typical Myeloproliferative Neoplasms enrolment sits around 120 participants.

    Median target enrolment is 120 among the 9 trials that report a genuine target (sentinel values excluded). 4 of those (44.4%) plan for fewer than 100 participants.

  4. Myeloproliferative Neoplasms research is mostly interventional.

    9 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 23

Open and recent trials

9 total, page 1 of 1

RECRUITING Phase 2 300 participants

Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

Masonic Cancer Center, University of Minnesota

NCT03314974

RECRUITING Phase 1 230 participants

A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms

Incyte Corporation

NCT06034002

RECRUITING Phase 1 218 participants

Study of INCA036978 in Participants With Myeloproliferative Neoplasms

Incyte Corporation

NCT07441694

RECRUITING Phase 1 186 participants

A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms

Incyte Corporation

NCT06313593

RECRUITING Phase 1 120 participants

A Study to Evaluate INCA035784 in Participants With Myeloproliferative Neoplasms

Incyte Corporation

NCT07008118

RECRUITING Phase 1 18 participants

Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation

University of Chicago

NCT06291987

ACTIVE NOT RECRUITING Phase 2 33 participants

Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders

Memorial Sloan Kettering Cancer Center

NCT04761770

ACTIVE NOT RECRUITING Phase 1 25 participants

A Phase 1 Trial of CD25/Treg-depleted DLI Plus Ipilimumab for Myeloid Disease Relapse After Matched-HCT

Dana-Farber Cancer Institute

NCT03912064

COMPLETED Phase 2 82 participants

Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Cancer

Alliance for Clinical Trials in Oncology

NCT00053196

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 3

Named interventions

Most-linked intervention names on Myeloproliferative Neoplasms records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Standard disease-directed therapy Drug
2 trials
Ruxolitinib Drug
2 trials
anti-thymocyte globulin Biological
1 trials
CD25hi Treg depleted DLI Biological
1 trials
busulfan Drug
1 trials
methotrexate Drug
1 trials
Allogeneic CD34+ selected stem cells Procedure
1 trials
conditioning regimen Drug
1 trials

US sites by state

Facility locations filed on Myeloproliferative Neoplasms trials. A trial with sites in several states counts in each.

New York 6 trials
California 5 trials
Texas 4 trials
North Carolina 4 trials
Maryland 4 trials
Massachusetts 4 trials
Florida 4 trials
Tennessee 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Myeloproliferative Neoplasms page

9 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 6 Myeloproliferative Neoplasms trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Incyte Corporation sponsors the most Myeloproliferative Neoplasms trials on record, review their full trial history before evaluating a specific study. See Incyte Corporation's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Myeloproliferative Neoplasms condition card totals 9 registered trials; most-linked intervention Standard disease-directed therapy; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.