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Musculoskeletal Pain: early-phase trial registry
14 of 38 indexed Musculoskeletal Pain trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #393 of 28,707 conditions by registered trial count.
38 US clinical trials · 14 currently recruiting · #393 of 28,707 conditions by registered trial count
Musculoskeletal Pain: 38 US clinical trials tracked, 14 recruiting.
Musculoskeletal Pain is the subject of 38 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 3 of these trials.
Enrollment posture brief
Registry condition musculoskeletal-pain
OPEN 14 | RECR 37% | LATE 1 | EARLY 4 | RANK #393 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Alcohol Consumption (37% recruiting · 19 trials)
Musculoskeletal Pain lists 14 open slots (37% of 38 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Musculoskeletal Pain on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Musculoskeletal Pain is recruiting below its size-band peers.
14 of 38 indexed trials (36.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Musculoskeletal Pain trials is spread across many organizations.
VA Office of Research and Development accounts for 3 of 38 trials (7.9%). 29 distinct sponsors appear on at least one study for this condition label.
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Typical Musculoskeletal Pain enrolment sits around 93 participants.
Median target enrolment is 93 among the 38 trials that report a genuine target (sentinel values excluded). 21 of those (55.3%) plan for fewer than 100 participants.
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Musculoskeletal Pain research is mostly interventional.
35 interventional and 3 observational studies make up this index (92.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
38 total, page 1 of 1
Targeted Realtime Assessment of Chronic Pain in Youth
Stanford University
NCT06867757
Overlapping Pain Trajectory Study
Children's Hospital Medical Center, Cincinnati
NCT05752396
Supraspinal Processing of Sensory Aspects of Pain
Children's Hospital Medical Center, Cincinnati
NCT05814497
Equipping Patients Using Interventions for Pain and Depression
Indiana University
NCT06500780
Online Yoga vs Acceptance and Commitment Therapy for Treating Chronic Musculoskeletal Pain
Palo Alto Veterans Institute for Research
NCT06704061
MOTIVATE to Improve Outcomes for Older Veterans With Musculoskeletal Pain and Depression
VA Office of Research and Development
NCT05220202
Eastern Principles Acceptance and Commitment Therapy For Injury Prevention Among Nurses and Nursing Aides
Bowling Green State University
NCT06813495
Improving Health for Older Adults With Pain Through Engagement
Massachusetts General Hospital
NCT06119698
Mechanisms and Modulation of Pain Modulatory Capacity
University of Florida
NCT04441619
The PROACTIVE Study for Black Elders
University of Florida
NCT06512727
Phase 1 Pilot of a Pragmatic Trial of EAET for Veterans With Chronic Pain
University of California, Los Angeles
NCT07218757
Neural Mechanisms of Light Driven Analgesia
University of North Carolina, Chapel Hill
NCT07245303
Virtual Reality (VR) Self-Hypnosis Software
Icahn School of Medicine at Mount Sinai
NCT06398847
Group Medical Visits and Chiropractic Care for Older Adults With Chronic Spine Pain
Brigham and Women's Hospital
NCT06632535
PEACE: Comparing Chronic Pain Treatment Options
Memorial Sloan Kettering Cancer Center
NCT02979574
SPRINT: Signature for Pain Recovery IN Teens
Stanford University
NCT04285112
Osteopathic Manipulation Makes a Neuropsychological Difference
Midwestern University
NCT04058431
Impact of Mesenchymal Stem Cells in Knee Osteoarthritis
University Hospitals Cleveland Medical Center
NCT03477942
Trial Outcomes for Massage: Caregiver-Assisted vs. Therapist-Treated
VA Office of Research and Development
NCT03100539
Acetaminophen (APAP) +/- Oxycodone
Montefiore Medical Center
NCT04122443
Hypnosis to Reduce Aromatase Inhibitor Pain and Improve Adherence
Icahn School of Medicine at Mount Sinai
NCT02657993
Optimizing Psychotherapy for Older Veterans With Chronic Pain
VA Office of Research and Development
NCT03918642
Soft Active Back Exosuit to Reduce Workplace Back Pain
Wyss Institute at Harvard University
NCT05802914
Pain Catastrophizing as a Cause for Systemic Inflammation
Beth Darnall, PhD
NCT00823147
The Pain & Stress Interview Study for People With Chronic Pain
Mark A. Lumley
NCT04498663
Multimodal Management of Neck and Back Pain in the Emergency Department (Multi-ED)
Duke University
NCT05221125
Altering The Transition From Acute to Chronic Pain (ATTAC-Pain)
Rhode Island Hospital
NCT03315533
Vitamin D to ENhance TraUma REcovery
University of North Carolina, Chapel Hill
NCT05458024
5-minute Mindful Pain Management Strategy
Florida State University
NCT06394765
Omega 7 Oil and Inflammatory Biomarker Study
Bastyr University
NCT03669575
Regional Manual Therapy and Motor Control Exercise for Chronic Low Back Pain
University of Texas Southwestern Medical Center
NCT02170753
Effects of Osteopathic Manipulative Treatment and Bio Electro-Magnetic Regulation Therapy on Low Back Pain in Adults.
Lake Erie College of Osteopathic Medicine
NCT04704375
Pain Rehabilitation Virtual Reality (PRVR): Innovations to Enhance Mobility in the Presence of Pain
Stanford University
NCT04636177
GET Living: Graded Exposure Treatment for Children and Adolescents With Chronic Pain
Boston Children's Hospital
NCT01974791
At-Home Telehealth Yoga for Treating Chronic Pain in People With Alzheimer's Disease and Their Caregiver's
Palo Alto Veterans Institute for Research
NCT04512040
Surgeon Core-strengthening Program as a Modifier for Exertion Associated With Vaginal Surgery
Loyola University
NCT06525701
Veteran Ear Acupuncture Pilot Project
Chillicothe VA Medical Center
NCT04208659
Enhanced Biofeedback for Musculoskeletal Pain
University of Tul
NCT02920853
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 2 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Musculoskeletal Pain records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Musculoskeletal Pain trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Musculoskeletal Pain page
38 registered trials, 14 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 14 Musculoskeletal Pain trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Musculoskeletal Pain trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Musculoskeletal Pain condition card totals 38 registered trials; most-linked intervention GET Living; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.