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NCT04441619 · ClinicalTrials.gov registry record · NA

Mechanisms and Modulation of Pain Modulatory Capacity

A NA study of Musculoskeletal Pain, sponsored by University of Florida.

Recruiting
Registry status
NA
Development phase
180
Enrollment target
1
Study location

NCT04441619: Recruiting NA study of Musculoskeletal Pain, sponsored by University of Florida.

NCT04441619 is a NA study of Musculoskeletal Pain that is actively recruiting participants, run by University of Florida. The registered enrollment target is 180 participants, above the 151-participant average among 37 other Musculoskeletal Pain trials with a reported enrollment target (19% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04441619, a NA study of Musculoskeletal Pain, is actively recruiting participants, sponsored by University of Florida.

RECRUITING
Registry status
NA
Development phase
180 participants
Enrollment target
1
Study location

Study Summary

This project proposes to understand the sources of pain variability, and demonstrate that pain variability represents fluctuation in natural pain management. The project further proposes to determine if endogenous capacity to modulate pain can be trained to maximize their body's ability to manage pain, much as the way in which athletic performance can be trained.

Primary Outcome

Pain during movement and pain at rest using the visual analog scale (VAS). Scores are recorded every day by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain.

Conditions Studied

Interventions

  • BEHAVIORAL Delayed onset muscle soreness.

Study Locations (1)

Florida

  • Unversity of Florida - Gainesville

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2020-11-30
Est. Completion 2026-04-30
Phase NA
University of Florida

1,106 total trials

What NCT04441619 shows while recruiting

NCT04441619 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, above the 151-participant average among 37 other Musculoskeletal Pain trials with a reported enrollment target (19% higher).

The record links to 1 condition, with Musculoskeletal Pain appearing as the primary indexed condition, and to 1 intervention - of which Delayed onset muscle soreness. is the first listed.

NCT04441619 reports a single indexed study location in Florida.

Frequently Asked Questions

What is clinical trial NCT04441619 about?

NCT04441619 is a clinical study titled "Mechanisms and Modulation of Pain Modulatory Capacity". This project proposes to understand the sources of pain variability, and demonstrate that pain variability represents fluctuation in natural pain management. The project further proposes to determine if endogenous capacity to modulate pain can be trained to maximize their body's ability to manage pa...

What is the current status of trial NCT04441619?

This trial is currently recruiting. It is a NA study. The enrollment target is 180 participants. The study started on 2020-11-30. Estimated completion is 2026-04-30.

What conditions does trial NCT04441619 study?

This clinical trial studies the following conditions: Musculoskeletal Pain.

What interventions are being tested in trial NCT04441619?

The interventions under investigation include: Delayed onset muscle soreness. (BEHAVIORAL).

Who is sponsoring clinical trial NCT04441619?

This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04441619 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Musculoskeletal Pain

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04441619's enrollment target sits among peer trials

180 14th of 37 higher than 24 of 37 other Musculoskeletal Pain trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Musculoskeletal Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04441619, the US trial registry maintained by the National Library of Medicine. NCT04441619 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.