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ClinicalTrials.gov 7 recruiting now official registry

Multiple Myeloma in Relapse clinical trials

7 of 13 indexed Multiple Myeloma in Relapse trials are currently recruiting.

13 US clinical trials · 7 currently recruiting

Multiple Myeloma in Relapse is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Oncotherapeutics, running 2 of these trials.

The research picture

Multiple Myeloma in Relapse has 13 registered US clinical trials, 7 of them open to new participants right now, about 54% of the total.

7
recruiting participants now
54%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: Oncotherapeutics
Phase 16Phase 26

Active & Recent Trials

13 total, page 1 of 1

RECRUITING Phase 2 43 participants

Daratumumab, Carfilzomib, Pomalidomide, Dexamethasone In MM

Andrew Yee, MD

NCT04176718

RECRUITING Phase 2 39 participants

A Study of Venetoclax in Combination With Isatuximab and Dexamethasone for Relapsed/Refractory Multiple Myeloma

Oncotherapeutics

NCT06115135

RECRUITING Phase 1 30 participants

LMY-920 for Treatment of Relapsed or Refractory Myeloma

Luminary Therapeutics

NCT05546723

RECRUITING Phase 1 30 participants

A Trial of Selinexor, Ruxolitinib and Methylprednisolone

Oncotherapeutics

NCT06225310

RECRUITING Phase 2 27 participants

HCMT/MM2401: Ph2 Study of Selinexor + Bispecific Antibody for RRMM

Duke University

NCT06822972

RECRUITING Phase 2 23 participants

Subcutaneous Talquetamab in Elderly Patients With Multiple Myeloma in Early Relapse

Larysa Sanchez

NCT06827860

RECRUITING Phase 1 18 participants

TriPRIL CAR T Cells in Multiple Myeloma

Marcela V. Maus, M.D.,Ph.D.

NCT05020444

ACTIVE NOT RECRUITING 200 participants

Impact of a Health Technology Intervention on Patient Activation in Multiple Myeloma

All4Cure

NCT05673083

ACTIVE NOT RECRUITING Phase 1 100 participants

Study of HPN217 in Participants With Relapsed/Refractory Multiple Myeloma MK-4002 (MK-4002-001)

Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

NCT04184050

ACTIVE NOT RECRUITING Phase 1 52 participants

Ixazomib + Pomalidomide + Dexamethasone In MM

Omar Nadeem, MD

NCT04094961

ACTIVE NOT RECRUITING Phase 2 25 participants

Elotuzumab, Pomalidomide, & Dexamethasone (Elo-Pom-Dex) With Second Autologous Stem Cell Transplantation for Relapsed Multiple Myeloma

Washington University School of Medicine

NCT03030261

ACTIVE NOT RECRUITING Phase 2 18 participants

Personalized Selinexor-based Therapy for Relapsed/Refractory Multiple Myeloma

University of Colorado, Denver

NCT04925193

COMPLETED Phase 1 14 participants

Study of Ibrutinib in Combination With Revlimid/Dexamethasone in Relapsed/Refractory Multiple Myeloma

Alliance Foundation Trials

NCT03702725

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 6

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Multiple Myeloma in Relapse Trial Landscape

13 indexed Multiple Myeloma in Relapse studies · 7 recruiting (54%).

Phase mix: 0 late (III/IV) vs 12 early (I/II).

Top sponsor: Oncotherapeutics (2 trials), 9 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Multiple Myeloma in Relapse?

PlainTrial tracks 13 US clinical trials for Multiple Myeloma in Relapse, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Multiple Myeloma in Relapse?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.