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ClinicalTrials.gov 10 recruiting now early-phase tilt small index

Metastatic Prostate Adenocarcinoma: early-phase trial registry

10 of 19 indexed Metastatic Prostate Adenocarcinoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #902 of 28,707 conditions by registered trial count.

19 US clinical trials · 10 currently recruiting · #902 of 28,707 conditions by registered trial count

Metastatic Prostate Adenocarcinoma: 19 US clinical trials tracked, 10 recruiting.

Metastatic Prostate Adenocarcinoma is the subject of 19 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 17 in Phase 1-2 (earlier-stage). The most active sponsor is Alliance for Clinical Trials in Oncology, running 2 of these trials.

Enrollment posture brief

Registry condition metastatic-prostate-adenocarcinoma

OPEN 10 | RECR 53% | LATE 2 | EARLY 17 | RANK #902 | SPON 2

Nearest open-share peer: Colorectal Cancer Metastatic (53% recruiting · 19 trials)

Metastatic Prostate Aden (th…53%Amyotrophic Lateral Sclerosi52.6%Anesthesia, Local42.1%Alcohol Consumption36.8%Attention Deficit Hyperactiv26.3%
Open-enrollment share among volume-matched conditions near Metastatic Prostate Adenocarcinoma

Metastatic Prostate Adenocarcinoma lists 10 open slots (53% of 19 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Metastatic Prostate Adenocarcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Metastatic Prostate Adenocarcinoma is recruiting above its size-band peers.

    10 of 19 indexed trials (52.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Metastatic Prostate Adenocarcinoma trials is spread across many organizations.

    Alliance for Clinical Trials in Oncology accounts for 2 of 19 trials (10.5%). 16 distinct sponsors appear on at least one study for this condition label.

  3. Most Metastatic Prostate Adenocarcinoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 47 among the 19 trials that report a genuine target (sentinel values excluded). 16 of those (84.2%) plan for fewer than 100 participants.

  4. Metastatic Prostate Adenocarcinoma research is mostly interventional.

    19 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 211Phase 32

Open and recent trials

19 total, page 1 of 1

RECRUITING Phase 3 1,260 participants

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

Alliance for Clinical Trials in Oncology

NCT06931340

RECRUITING Phase 2 200 participants

Modifying Metabolic Syndrome and Cardiovascular Risk for Prostate Cancer Patients on ADT Using a Risk Factor Modification Program and Continuous Fitbit Monitoring

M.D. Anderson Cancer Center

NCT05054296

RECRUITING Phase 2 70 participants

Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer

City of Hope Medical Center

NCT04734730

RECRUITING Phase 2 69 participants

Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study

University of Washington

NCT06039371

RECRUITING Phase 1 48 participants

Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer

Fred Hutchinson Cancer Center

NCT06236139

RECRUITING Phase 2 47 participants

Bipolar Androgen Therapy (BAT) and Radium-223 (RAD) in Metastatic Castration-resistant Prostate Cancer (mCRPC)

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT04704505

RECRUITING Phase 1 39 participants

Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer

University of Michigan Rogel Cancer Center

NCT06616155

RECRUITING Phase 2 33 participants

Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer, The AtezoCab Trial

University of Utah

NCT05168618

RECRUITING Phase 1 30 participants

Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

Vadim S Koshkin

NCT05113537

RECRUITING Phase 2 15 participants

Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer

Fred Hutchinson Cancer Center

NCT06145633

ACTIVE NOT RECRUITING Phase 1 145 participants

Testing the Safety of Different Doses of Olaparib Given Radium-223 for Men With Advanced Prostate Cancer With Bone Metastasis

National Cancer Institute (NCI)

NCT03317392

ACTIVE NOT RECRUITING Phase 2 84 participants

A Study to Evaluate Hypofractionated Proton Therapy or IMRT for Recurrent, Oligometastatic Prostate Cancer

Mayo Clinic

NCT04190446

ACTIVE NOT RECRUITING Phase 3 61 participants

A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With Metastatic Prostate Cancer That Has Become Resistant To Testosterone-Deprivation Therapy

Alliance for Clinical Trials in Oncology

NCT04455750

ACTIVE NOT RECRUITING Phase 2 61 participants

ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer

Rahul Aggarwal

NCT04471974

ACTIVE NOT RECRUITING Phase 2 28 participants

Antiandrogen Therapy and SBRT in Treating Patients With Recurrent, Metastatic Prostate Cancer

Jonsson Comprehensive Cancer Center

NCT03902951

ACTIVE NOT RECRUITING Phase 2 8 participants

CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations

Mayo Clinic

NCT05689021

ACTIVE NOT RECRUITING Phase 1 7 participants

Cyclophosphamide and Dexamethasone for the Treatment of Metastatic Castration Resistant Prostate Cancer

Rashmi Verma, MD

NCT05479578

COMPLETED Phase 2 36 participants

Genetic and Molecular Mechanisms in Assessing Response in Patients With Prostate Cancer Receiving Enzalutamide Therapy

OHSU Knight Cancer Institute

NCT02099864

COMPLETED Phase 1 16 participants

Evaluation of PSMA Antagonist Produced by Two Different Methods

Weill Medical College of Cornell University

NCT04685811

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 11
Phase 3 2

Named interventions

Most-linked intervention names on Metastatic Prostate Adenocarcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Computed Tomography Procedure
8 trials
Biospecimen Collection Procedure
6 trials
Bone Scan Procedure
5 trials
Enzalutamide Drug
4 trials
Leuprolide Acetate Drug
3 trials
Questionnaire Administration Other
3 trials
Biopsy Procedure Procedure
3 trials
Magnetic Resonance Imaging Procedure
3 trials

US sites by state

Facility locations filed on Metastatic Prostate Adenocarcinoma trials. A trial with sites in several states counts in each.

California 9 trials
Washington 3 trials
Michigan 3 trials
Arizona 3 trials
Minnesota 2 trials
Maryland 2 trials
Illinois 2 trials
Utah 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Metastatic Prostate Adenocarcinoma page

19 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Metastatic Prostate Adenocarcinoma condition card totals 19 registered trials; most-linked intervention Computed Tomography; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.