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2026 data Public-data reference. official source

Metastasis

Open-data reference.

16 US clinical trials · 10 currently recruiting

Active & Recent Trials

RECRUITING Phase 1 360 participants

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

Merck Sharp & Dohme

NCT06863272

RECRUITING Phase 1 126 participants

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

7 Hills Pharma

NCT06362369

RECRUITING NA 100 participants

Clinical Nurse Specialist Led Early Palliative Survivorship Care for Patients With Advanced Cancer

Good Samaritan Hospital Medical Center, New York

NCT05947695

RECRUITING Phase 1 58 participants

ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer

UNC Lineberger Comprehensive Cancer Center

NCT05542407

RECRUITING Phase 1 46 participants

Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases

Baptist Health South Florida

NCT05789589

RECRUITING Phase 2 45 participants

A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma

Memorial Sloan Kettering Cancer Center

NCT07477457

RECRUITING Phase 1 42 participants

Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer

Icahn School of Medicine at Mount Sinai

NCT05095207

RECRUITING Early Phase 1 30 participants

Feasibility Study of Personalized Ultra-fractionated Stereotactic Ablative Radiotherapy (PULSAR) for Cancers of the Central Lung

University of Texas Southwestern Medical Center

NCT06712745

RECRUITING Phase 2 26 participants

Definitive Radiation for High-Risk Spine Metastases

Stony Brook University

NCT06165419

RECRUITING Phase 1 21 participants

Study of PAT in Patients With Solid Tumor Cancers

Masonic Cancer Center, University of Minnesota

NCT05338658

ACTIVE NOT RECRUITING Phase 2 120 participants

Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

Aadi Bioscience

NCT05103358

ACTIVE NOT RECRUITING Phase 2 12 participants

Personalized Ultra-fractionated Stereotactic Adaptive Radiotherapy for Metastatic Cervical Cancer

University of Texas Southwestern Medical Center

NCT05021237

COMPLETED 183 participants

EchoTip AcuCore Post-Market Clinical Study

Cook Research Incorporated

NCT06358001

COMPLETED Phase 3 178 participants

A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine

Nektar Therapeutics

NCT02915744

COMPLETED Phase 2 34 participants

First-Line Treatment of Advanced Bladder Cancer Randomized vs. Gemcitabine ± Vinflunine in Patients Ineligible to Receive Cisplatin-Based Therapy

Bristol-Myers Squibb

NCT00389155

COMPLETED Phase 1 29 participants

Effect of Samarium on the Relief of Pain Due to Vertebral Metastases

New York Presbyterian Brooklyn Methodist Hospital

NCT00374751

Phase Distribution

PhaseTrial count
Early Phase 1 8
Phase 2 5
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Metastasis Trial Landscape

ClinicalTrials.gov lists 16 US studies indexed under Metastasis, and 10 of those are currently open to recruitment — roughly 63% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Metastasis shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 13 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Metastasis is led by University of Texas Southwestern Medical Center with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 16 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Metastasis?

PlainTrial tracks 16 US clinical trials for Metastasis, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Metastasis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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