Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 10 recruiting now early-phase tilt small index

Metastasis: early-phase trial registry

10 of 16 indexed Metastasis trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,060 of 28,707 conditions by registered trial count.

16 US clinical trials · 10 currently recruiting · #1,060 of 28,707 conditions by registered trial count

Metastasis: 16 US clinical trials tracked, 10 recruiting.

Metastasis is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is University of Texas Southwestern Medical Center, running 2 of these trials.

Enrollment posture brief

Registry condition metastasis

OPEN 10 | RECR 63% | LATE 1 | EARLY 13 | RANK #1060 | SPON 2

Nearest open-share peer: Advanced Gastroesophageal Junction Adenocarcinoma (63% recruiting · 8 trials)

Metastasis (this)63%Adolescent62.5%Alcohol Intoxication56.3%AL Amyloidosis43.8%Allergy18.8%
Open-enrollment share among volume-matched conditions near Metastasis

Metastasis lists 10 open slots (63% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Metastasis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Metastasis is recruiting above its size-band peers.

    10 of 16 indexed trials (62.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Metastasis trials is spread across many organizations.

    University of Texas Southwestern Medical Center accounts for 2 of 16 trials (12.5%). 15 distinct sponsors appear on at least one study for this condition label.

  3. Most Metastasis trials plan to enrol fewer than 100 people.

    Median target enrolment is 46 among the 16 trials that report a genuine target (sentinel values excluded). 10 of those (62.5%) plan for fewer than 100 participants.

  4. Metastasis research is mostly interventional.

    15 interventional and 1 observational studies make up this index (93.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 18Phase 25Phase 31

Open and recent trials

16 total, page 1 of 1

RECRUITING Phase 1 360 participants

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

Merck Sharp & Dohme

NCT06863272

RECRUITING Phase 1 126 participants

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

7 Hills Pharma

NCT06362369

RECRUITING NA 100 participants

Clinical Nurse Specialist Led Early Palliative Survivorship Care for Patients With Advanced Cancer

Good Samaritan Hospital Medical Center, New York

NCT05947695

RECRUITING Phase 1 58 participants

ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer

UNC Lineberger Comprehensive Cancer Center

NCT05542407

RECRUITING Phase 1 46 participants

Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases

Baptist Health South Florida

NCT05789589

RECRUITING Phase 2 45 participants

A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma

Memorial Sloan Kettering Cancer Center

NCT07477457

RECRUITING Phase 1 42 participants

Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer

Icahn School of Medicine at Mount Sinai

NCT05095207

RECRUITING Early Phase 1 30 participants

Feasibility Study of Personalized Ultra-fractionated Stereotactic Ablative Radiotherapy (PULSAR) for Cancers of the Central Lung

University of Texas Southwestern Medical Center

NCT06712745

RECRUITING Phase 2 26 participants

Definitive Radiation for High-Risk Spine Metastases

Stony Brook University

NCT06165419

RECRUITING Phase 1 21 participants

Study of PAT in Patients With Solid Tumor Cancers

Masonic Cancer Center, University of Minnesota

NCT05338658

ACTIVE NOT RECRUITING Phase 2 120 participants

Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

Aadi Bioscience

NCT05103358

ACTIVE NOT RECRUITING Phase 2 12 participants

Personalized Ultra-fractionated Stereotactic Adaptive Radiotherapy for Metastatic Cervical Cancer

University of Texas Southwestern Medical Center

NCT05021237

COMPLETED 183 participants

EchoTip AcuCore Post-Market Clinical Study

Cook Research Incorporated

NCT06358001

COMPLETED Phase 3 178 participants

A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine

Nektar Therapeutics

NCT02915744

COMPLETED Phase 2 34 participants

First-Line Treatment of Advanced Bladder Cancer Randomized vs. Gemcitabine ± Vinflunine in Patients Ineligible to Receive Cisplatin-Based Therapy

Bristol-Myers Squibb

NCT00389155

COMPLETED Phase 1 29 participants

Effect of Samarium on the Relief of Pain Due to Vertebral Metastases

New York Presbyterian Brooklyn Methodist Hospital

NCT00374751

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 5
Phase 3 1

Named interventions

Most-linked intervention names on Metastasis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Gemcitabine Drug
2 trials
Samarium (153SM) Drug
1 trials
NKTR-102 Drug
1 trials
EchoTip AcuCore Device
1 trials
Vinflunine Drug
1 trials
Ultra-fractionated radiation therapy Radiation
1 trials
Ixabepilone Drug
1 trials
Peptide Alarm Therapy (PAT) Drug
1 trials

US sites by state

Facility locations filed on Metastasis trials. A trial with sites in several states counts in each.

New York 6 trials
Texas 5 trials
Florida 5 trials
California 5 trials
Arizona 3 trials
Washington 2 trials
Tennessee 2 trials
Pennsylvania 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Metastasis page

16 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Metastasis condition card totals 16 registered trials; most-linked intervention Gemcitabine; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.