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ClinicalTrials.gov 6 recruiting now early-phase tilt

Metabolism: early-phase trial registry

6 of 20 indexed Metabolism trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #848 of 28,707 conditions by registered trial count.

20 US clinical trials · 6 currently recruiting · #848 of 28,707 conditions by registered trial count

Metabolism: 20 US clinical trials tracked, 6 recruiting.

Metabolism is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Texas Tech University, running 2 of these trials.

Enrollment posture brief

Registry condition metabolism

OPEN 6 | RECR 30% | LATE 0 | EARLY 5 | RANK #848 | SPON 2

Nearest open-share peer: Adrenocortical Carcinoma (30% recruiting · 10 trials)

Advanced or Metastatic Solid55%ALS50%Metabolism (this)30%Abdominal Pain25%Acute Myocardial Infarction25%
Open-enrollment share among volume-matched conditions near Metabolism

Metabolism lists 6 open slots (30% of 20 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Metabolism on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Metabolism is recruiting below its size-band peers.

    6 of 20 indexed trials (30%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Metabolism trials is spread across many organizations.

    Texas Tech University accounts for 2 of 20 trials (10%). 19 distinct sponsors appear on at least one study for this condition label.

  3. Most Metabolism trials plan to enrol fewer than 100 people.

    Median target enrolment is 30 among the 20 trials that report a genuine target (sentinel values excluded). 16 of those (80%) plan for fewer than 100 participants.

  4. Metabolism research is mostly interventional.

    16 interventional and 4 observational studies make up this index (80% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 21

Open and recent trials

20 total, page 1 of 1

RECRUITING NA 250,000 participants

Personalized Responses to Dietary Composition Trial 3

Zoe Global Limited

NCT04735835

RECRUITING 400 participants

Caloric Balance Markers Study

Institute for Systems Biology

NCT07141537

RECRUITING Phase 2 200 participants

NAUTICAL: Effect of Natriuretic Peptide Augmentation on Cardiometabolic Health in Black Individuals

University of Alabama at Birmingham

NCT04055428

RECRUITING 40 participants

Studying Phenotypic Risks for Obesity and Underlying Traits in Young Infants

Pennington Biomedical Research Center

NCT07096011

RECRUITING NA 30 participants

GLYLO Supplement Pilot Trial on Glycation and Aging in Postmenopausal Women

Buck Institute for Research on Aging

NCT06813261

RECRUITING NA 12 participants

Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells

Vanderbilt University Medical Center

NCT06930976

ACTIVE NOT RECRUITING NA 1,017 participants

Study of Clinical Response to Acute Metformin By Leveraging Evaluations During a Mixed Meal Tolerance Test for Exploring Glycemia and GeneticS

Massachusetts General Hospital

NCT02087826

ACTIVE NOT RECRUITING Early Phase 1 15 participants

Effects of Casein Protein on Metabolism When Taken Prior to Sleep and in the Morning

Ohio University

NCT06250270

COMPLETED 65 participants

Influence of Age and Sex on Alcohol Metabolism and Acute Responses

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT00070577

COMPLETED 64 participants

Pilot Data Collection for Activity, Adiposity, and Appetite in Adolescents

Children's Mercy Hospital Kansas City

NCT03157063

COMPLETED NA 64 participants

Development of Novel Therapies for NIDDM

Duke University

NCT01905722

COMPLETED NA 30 participants

A Study to Examine the Effect of a Thermogenic Energy Drink in Healthy Adults

Rowdy Energy

NCT05061797

COMPLETED NA 28 participants

Metabolic Effects of a Thermogenic Ready-to-drink Beverage

Texas Tech University

NCT05194475

COMPLETED NA 26 participants

Interaction Between Cannabidiol, Meal Ingestion, and Liver Function

Colorado State University

NCT04971837

COMPLETED NA 19 participants

Effects of a Caffeine- and Protein-Containing Coffee Beverage on Metabolism and Muscular Performance

Texas Tech University

NCT04180787

COMPLETED NA 10 participants

The Effects of Gyngerlean Supplementation on Energy Expenditure

Nova Southeastern University

NCT06805201

COMPLETED NA 8 participants

Duration of Physical Inactivity and Postprandial Lipid Metabolism

University of Texas at Austin

NCT06407050

COMPLETED Phase 1 8 participants

Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-Simufilam Following a Single Oral Dose in Healthy Male Subjects

Cassava Sciences

NCT06195319

COMPLETED Phase 1 6 participants

RI-AME Study OF [ISOTHIAZOLYL-3-14C]-LURASIDONE

Sumitomo Pharma America

NCT01082146

COMPLETED Phase 1 6 participants

Investigate Absorption, Metabolism and Excretion of [14C}-Proellex Following Single Oral Dose in Healthy Females

Repros Therapeutics

NCT00881062

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 1

Named interventions

Most-linked intervention names on Metabolism records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Proellex Drug
1 trials
Thermogenic Energy Drink - Active Study Product Formula Dietary supplement
1 trials
7 Tesla Other
1 trials
3 Tesla Other
1 trials
Cannabidiol (CBD) Isolate in water formulation Dietary supplement
1 trials
Cannabidiol (CBD) Gum Arabic, sorbitol base formulation Dietary supplement
1 trials
Cannabidiol (CBD) Gum Arabic, maltodextrin base formulation Dietary supplement
1 trials
Cannabidiol (CBD) Oil based tincture formulation Dietary supplement
1 trials

US sites by state

Facility locations filed on Metabolism trials. A trial with sites in several states counts in each.

Texas 4 trials
Wisconsin 3 trials
Massachusetts 2 trials
Washington 1 trials
Tennessee 1 trials
Ohio 1 trials
Missouri 1 trials
Maryland 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Metabolism page

20 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Metabolism condition card totals 20 registered trials; most-linked intervention Proellex; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.