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NCT06195319 · ClinicalTrials.gov registry record · Phase 1

Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-Simufilam Following a Single Oral Dose in Healthy Male Subjects

A Phase 1 study of Metabolism and Absorption, sponsored by Cassava Sciences.

Completed
Registry status
Phase 1
Development phase
8
Enrollment target
1
Study location

NCT06195319 is a Phase 1 study of Metabolism and Absorption that has completed, run by Cassava Sciences. The registered enrollment target is 8 participants, below the 13,265-participant average among 19 other Metabolism trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06195319, a Phase 1 study of Metabolism and Absorption, has completed, sponsored by Cassava Sciences.

COMPLETED
Registry status
Phase 1
Development phase
8 participants
Enrollment target
1
Study location

Study Summary

To evaluate the absorption, metabolism, and excretion of \[14C\]-simufilam in healthy male subjects following a single oral administration of 100 mg of (approximately 100 µCi) \[14C\]-simufilam.

Interventions

  • DRUG Simufilam

Study Locations (1)

Wisconsin

  • Fortrea - Madison

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2024-02-07
Est. Completion 2024-03-27
Phase Phase 1

Sponsor

Cassava Sciences

9 total trials

What the Registry Record Tells You About NCT06195319

The ClinicalTrials.gov registry entry for NCT06195319 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 8 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 13,265-participant average among 19 other Metabolism trials with a reported enrollment target (100% lower). The listed sponsor is Cassava Sciences, which has 9 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Metabolism appearing as the primary indexed condition, and to 1 intervention - of which Simufilam is the first listed.

NCT06195319 reports 1 study location spanning 1 distinct geographic area - top geographies include Wisconsin.

Frequently Asked Questions

What is clinical trial NCT06195319 about?

NCT06195319 is a clinical study titled "Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-Simufilam Following a Single Oral Dose in Healthy Male Subjects". To evaluate the absorption, metabolism, and excretion of \[14C\]-simufilam in healthy male subjects following a single oral administration of 100 mg of (approximately 100 µCi) \[14C\]-simufilam.

What is the current status of trial NCT06195319?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2024-02-07. Estimated completion is 2024-03-27.

What conditions does trial NCT06195319 study?

This clinical trial studies the following conditions: Metabolism, Absorption, Excretion.

What interventions are being tested in trial NCT06195319?

The interventions under investigation include: Simufilam (DRUG).

Who is sponsoring clinical trial NCT06195319?

This trial is sponsored by Cassava Sciences, which has 9 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06195319 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.