Repros Therapeutics

50 total trials 38 completed

Repros Therapeutics sponsors 50 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 38 completed. 13 of these trials are in Phase 3-4 (later-stage) and 37 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Secondary Hypogonadism, with 2 trials.

Trial Pipeline

50 total, page 1 of 1

TERMINATED Phase 2

An Extension Study of 12 mg Proellex® (Telapristone Acetate) Administered Orally in the Treatment of Premenopausal Women With Confirmed Symptomatic Uterine Fibroids

NCT02811159

COMPLETED Phase 2

A Multi-Center Study in Men With Acquired Hypogonadotropic Hypogonadism to Compare Changes in Body Composition and Metabolic Parameters With Diet and Exercise in Conjunction With Treatment With 12.5 mg or 25 mg Enclomiphene

NCT02651688

COMPLETED Phase 2

A Multi-Center, Parallel Design, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of 6 and 12 mg Proellex® (Telapristone Acetate) Administered Orally in the Treatment of Premenopausal Women With Confirmed Symptomatic Uterine Fibroids

NCT02301897

COMPLETED Phase 2

Safety and Efficacy of Telapristone Acetate (Proellex®) Administered Vaginally for the Treatment of Uterine Fibroids

NCT02323646

COMPLETED Phase 1

An Open-Label, Single-Dose Study to Assess the Absorption, Metabolism, Excretion, and Mass Balance of Radiolabeled Androxal in Healthy Male Subjects After Oral Administration

NCT02274181

COMPLETED Phase 1

An Open-Label Study to Evaluate the Effect of Age Upon the Pharmacokinetics of Androxal

NCT02169804

COMPLETED Phase 1

Comparison of Two Formulations of Proellex for Oral Administration

NCT02141061

COMPLETED Phase 1

Assessment of Drug-Drug Interactions of Androxal With Cytochrome P450 Isoenyzmes in Healthy Males

NCT01991327

COMPLETED Phase 3

A Randomized, Double Blind, Placebo-Controlled, Multi-Center Phase III Study in Men With Acquired Hypogonadotropic Hypogonadism to Compare Changes in Testosterone and Sperm Concentration Following Treatment With 12.5 mg or 25 mg Androxal or AndroGel 1.62%

NCT01993225

COMPLETED Phase 3

A Randomized, Double Blind, Placebo-Controlled, Multi-Center Phase III Study in Men With Acquired Hypogonadotropic Hypogonadism to Compare Changes in Testosterone and Sperm Concentration Following Treatment With 12.5 mg or 25 mg Androxal or AndroGel 1.62%

NCT01993212

COMPLETED Phase 1

Comparison of Two Formulations of Androxal

NCT01984398

COMPLETED Phase 1

A Dose Escalating Study to Determine the Tolerability and PK of a Single Dose of Androxal

NCT01959685

COMPLETED Phase 1

Comparison of Two Formulations of Proellex for Vaginal Administration

NCT01962805

COMPLETED Phase 1

Evaluation of Pharmacokinetic and Safety Profile of Androxal in Male Subjects With Impaired Renal Function

NCT01923857

COMPLETED Phase 1

Evaluation of the Pharmacokinetics and Safety of Androxal in Male Subjects With Impaired Hepatic Function

NCT01923870

COMPLETED Phase 2

Safety and Efficacy of Telapristone Acetate (Proellex®) in the Treatment of Pre-Menopausal Women With Confirmed, Symptomatic Endometriosis

NCT01728454

COMPLETED Phase 3

Phase III Study to Evaluate Morning Testosterone Normalization in Overweight Men With Secondary Hypogonadism

NCT01739595

COMPLETED Phase 2

Extension of Study ZPV-200

NCT01631903

COMPLETED Phase 3

Assessment of the Effects of Enclomiphene Citrate on Bone Mineral Density in Men With Secondary Hypogonadism

NCT01619683

COMPLETED Phase 3

Phase III Study to Evaluated Morning Testosterone Normalization in Men With Secondary Hypogonadism

NCT01532414

COMPLETED Phase 3

Safety Study of Enclomiphene Citrate in the Treatment of Men With Secondary Hypogonadism

NCT01534208

COMPLETED Phase 2

Evaluation of Safety, Pharmacokinetics, and Efficacy of Proellex Administered Vaginally in Women With Uterine Fibroids

NCT01451424

COMPLETED Phase 2

A One Year Open Label Study for the Treatment of Hypogonadism (Low Testosterone) in Men Who Have Completed ZA-203

NCT01386567

COMPLETED Phase 2

The Effect on Androxal Versus Androgel on Morning Testosterone in Men With Secondary Hypogonadism (Low Testosterone)

NCT01386606

COMPLETED Phase 2

Normalization of Morning Testosterone Levels in Men With Secondary Hypogonadism

NCT01270841

COMPLETED Phase 2

Study to Evaluate the Efficacy of Androxal in Controlling Blood Glucose in Men With Type-2 Diabetes Mellitus

NCT01191320

COMPLETED Phase 1

Determination of the Lowest, Safe and Effective Dose of Proellex

NCT01187043

COMPLETED Phase 1

Investigate Absorption, Metabolism and Excretion of [14C}-Proellex Following Single Oral Dose in Healthy Females

NCT00881062

TERMINATED Phase 3

Safety of 25 and 50 mg Proellex® in the Treatment of Women With Symptomatic Uterine Fibroids

NCT01069120

TERMINATED Phase 2

Study Evaluating the Safety and Efficacy of Proellex® in the Treatment of Endometriosis-extension Study

NCT00958412

TERMINATED Phase 3

Evaluating the Safety and Efficacy of Proellex® in Premenopausal Women With Symptomatic Uterine Fibroids

NCT00853567

TERMINATED Phase 1

Study to Evaluate Menses Induction in Women Administered Proellex

NCT00881608

COMPLETED Phase 1

Evaluate the Safety and PK of Proellex® in Female Patients With Impaired Hepatic Function and Healthy Adults

NCT00741273

TERMINATED Phase 1

Evaluate PK and Safety of Proellex® in Females With Various Stages of Impaired Renal Function and Healthy Females

NCT00787618

TERMINATED Phase 3

Multicenter Study Evaluating the Safety of Proellex® in Premenopausal Women With Uterine Fibroids

NCT00737282

COMPLETED Phase 1

Crossover Study of the Safety and PK Properties of Proellex®

NCT00749879

TERMINATED Phase 3

Evaluating the Safety and Efficacy of Proellex® (CDB-4124) in Premenopausal Women With Symptomatic Uterine Fibroids

NCT00735553

COMPLETED Phase 1

Open-Label, Multiple-Dose, Non-Randomized Study to Assess Drug-Drug Interactions of Proellex® in Female Subjects

NCT00741468

COMPLETED Phase 2

To Evaluate Sperm Parameters in Men With Secondary Hypogonadism Previously Treated With Topical Testosterone

NCT00706719

TERMINATED Phase 3

Safety and Efficacy of Proellex in Pre-menopausal Anemic Women With Symptomatic Uterine Fibroids

NCT00702702

TERMINATED Phase 2

An Extension Study Evaluating Safety and Efficacy of Proellex® In Women Who Have Previously Completed ZPU 003 Ext

NCT00958893

TERMINATED Phase 2

Pharmacokinetics, Safety and Efficacy Study of Proellex in Pre-menopausal Women With Symptomatic Uterine Fibroids

NCT00683917

COMPLETED Phase 1

Proellex® Pharmacokinetic Bridging Study II

NCT00620503

COMPLETED Phase 1

A Safety and Pharmacokinetic Study of Proellex®

NCT00619385

TERMINATED Phase 2

Safety and Efficacy Study to Evaluate Proellex in the Treatment of Premenopausal Women With Symptomatic Endometriosis

NCT00556075

COMPLETED Phase 1

Proellex Pharmacokinetics Bridging Study

NCT01067807

COMPLETED Phase 2

Extension Study of Proellex in Women Who Have Previously Completed Study ZPU 003

NCT00958334

COMPLETED Phase 3

Study to Evaluate the Safety and Efficacy of Androxal™ Treatment in Men With Secondary Hypogonadism

NCT00962637

COMPLETED Phase 3

Study to Evaluate the Safety and Efficacy of Androxal Treatment in Men With Secondary Hypogonadism

NCT01067365

COMPLETED Phase 2

Study of Proellex in Pre-menopausal Women With Symptomatic Uterine Fibroids

NCT00882258

Phase Distribution

PhaseTrial count
Phase 1 19
Phase 2 18
Phase 3 13

What the Pipeline for Repros Therapeutics Shows

According to the ClinicalTrials.gov registry, Repros Therapeutics is linked to 50 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 38 are already marked complete, representing roughly 76% of the total.

The phase mix for Repros Therapeutics reports 13 late-stage studies (Phase 3 and Phase 4 combined) and 37 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Repros Therapeutics is Secondary Hypogonadism with 2 linked trials, and 8 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.