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NCT05877729 · ClinicalTrials.gov registry record · NA

Intervention for Virologic Suppression in Youth

A NA study of Substance Use and HIV/AIDS, sponsored by University of California, San Francisco.

Active
Registry status
NA
Development phase
200
Enrollment target
1
Study location

NCT05877729: Active NA study of Substance Use and HIV/AIDS, sponsored by University of California, San Francisco.

NCT05877729 is a NA study of Substance Use and HIV/AIDS that is active but no longer recruiting, run by University of California, San Francisco. The registered enrollment target is 200 participants, below the 1,258-participant average among 88 other Substance Use trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05877729, a NA study of Substance Use and HIV/AIDS, is active but no longer recruiting, sponsored by University of California, San Francisco.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
200 participants
Enrollment target
1
Study location

Study Summary

The goal of this randomized clinical trial is to test the effect of a technology-based intervention with an Adaptive Treatment Strategy (ATS) among youth living with HIV (YLWH) (18-29 years old). This piloted and protocolized intervention combines: (1) brief weekly sessions with a counselor via a video-chat platform (video-counseling) to discuss mental health (MH), substance use (SU), HIV care engagement, and other barriers to care; and (2) a mobile health application (app) to address barriers such as ART forgetfulness and social isolation. Individuals who are not virologically suppressed will be randomized to video-counseling+app or standard of care (SOC). Through this study, the investigators will be able to: Aim 1: Test the efficacy of video-counseling+app vs SOC on virologic suppression in YLWH.The investigators will compare HIV virologic suppression of those randomized to the intervention vs control arms at 16 weeks via an RCT. Aim 2: Assess the impact of video-counseling+app vs SOC on MH and SU in YLWH. The investigators will evaluate the MH and SU differences between the intervention vs control arms at 16 weeks via an RCT. Aim 3: Explore an ATS to individualize the intervention by assigning the: 1. virologic "non-responders" in the intervention arm to intensified video-counseling+app for 16 more weeks, 2. virologic "responders" in the intervention arm to continue only app use for 16 more weeks. Researchers will compare the characteristics of virologic responders and non-responders to the intervention, individualization of the intervention based on these variables, and linkage to MH and SU treatment services among those in need to see if delivery of care is enhanced and impact on virologic suppression.

Primary Outcome

Investigators will compare HIV virologic suppression of those randomized to the intervention vs control arm. HIV virologic suppression will be evaluated using home collected Hemaspot test.

Conditions Studied

Substance Use HIV/AIDS Mental Health Issue Young Adult Mobile Health

Interventions

  • OTHER Standard of Care
  • BEHAVIORAL Video-counseling+app

Study Locations (1)

California

  • Division of Prevention Science, Center for AIDS Prevention Studies (CAPS) - San Francisco

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2023-11-29
Est. Completion 2026-12-31
Phase NA
University of California, San Francisco

1,713 total trials

What the registry record for NCT05877729 still lists

NCT05877729 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 1,258-participant average among 88 other Substance Use trials with a reported enrollment target (84% lower).

The record links to 5 conditions, with Substance Use appearing as the primary indexed condition, and to 2 interventions - of which Standard of Care is the first listed.

NCT05877729 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT05877729 about?

NCT05877729 is a clinical study titled "Intervention for Virologic Suppression in Youth". The goal of this randomized clinical trial is to test the effect of a technology-based intervention with an Adaptive Treatment Strategy (ATS) among youth living with HIV (YLWH) (18-29 years old). This piloted and protocolized intervention combines: (1) brief weekly sessions with a counselor via a vi...

What is the current status of trial NCT05877729?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2023-11-29. Estimated completion is 2026-12-31.

What conditions does trial NCT05877729 study?

This clinical trial studies the following conditions: Substance Use, HIV/AIDS, Mental Health Issue, Young Adult, Mobile Health.

What interventions are being tested in trial NCT05877729?

The interventions under investigation include: Standard of Care (OTHER), Video-counseling+app (BEHAVIORAL).

Who is sponsoring clinical trial NCT05877729?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05877729 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Substance Use

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05877729's enrollment target sits among peer trials

200 47th of 88 higher than 40 of 88 other Substance Use trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Substance Use trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT05877729, the US trial registry maintained by the National Library of Medicine. NCT05877729 (mid enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.