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NCT05877729 · ClinicalTrials.gov registry record · NA
Intervention for Virologic Suppression in Youth
A NA study of Substance Use and HIV/AIDS, sponsored by University of California, San Francisco.
- Active
- Registry status
- NA
- Development phase
- 200
- Enrollment target
- 1
- Study location
NCT05877729 is a NA study of Substance Use and HIV/AIDS that is active but no longer recruiting, run by University of California, San Francisco. The registered enrollment target is 200 participants, below the 1,258-participant average among 88 other Substance Use trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05877729, a NA study of Substance Use and HIV/AIDS, is active but no longer recruiting, sponsored by University of California, San Francisco.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this randomized clinical trial is to test the effect of a technology-based intervention with an Adaptive Treatment Strategy (ATS) among youth living with HIV (YLWH) (18-29 years old). This piloted and protocolized intervention combines: (1) brief weekly sessions with a counselor via a video-chat platform (video-counseling) to discuss mental health (MH), substance use (SU), HIV care engagement, and other barriers to care; and (2) a mobile health application (app) to address barriers such as ART forgetfulness and social isolation. Individuals who are not virologically suppressed will be randomized to video-counseling+app or standard of care (SOC). Through this study, the investigators will be able to: Aim 1: Test the efficacy of video-counseling+app vs SOC on virologic suppression in YLWH.The investigators will compare HIV virologic suppression of those randomized to the intervention vs control arms at 16 weeks via an RCT. Aim 2: Assess the impact of video-counseling+app vs SOC on MH and SU in YLWH. The investigators will evaluate the MH and SU differences between the intervention vs control arms at 16 weeks via an RCT. Aim 3: Explore an ATS to individualize the intervention by assigning the: 1. virologic "non-responders" in the intervention arm to intensified video-counseling+app for 16 more weeks, 2. virologic "responders" in the intervention arm to continue only app use for 16 more weeks. Researchers will compare the characteristics of virologic responders and non-responders to the intervention, individualization of the intervention based on these variables, and linkage to MH and SU treatment services among those in need to see if delivery of care is enhanced and impact on virologic suppression.
Conditions Studied
Interventions
- OTHER Standard of Care
- BEHAVIORAL Video-counseling+app
Study Locations (1)
California
- Division of Prevention Science, Center for AIDS Prevention Studies (CAPS) - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2023-11-29 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05877729
The ClinicalTrials.gov registry entry for NCT05877729 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,258-participant average among 88 other Substance Use trials with a reported enrollment target (84% lower). The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Substance Use appearing as the primary indexed condition, and to 2 interventions - of which Standard of Care is the first listed.
NCT05877729 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT05877729 about?
NCT05877729 is a clinical study titled "Intervention for Virologic Suppression in Youth". The goal of this randomized clinical trial is to test the effect of a technology-based intervention with an Adaptive Treatment Strategy (ATS) among youth living with HIV (YLWH) (18-29 years old). This piloted and protocolized intervention combines: (1) brief weekly sessions with a counselor via a vi...
What is the current status of trial NCT05877729?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2023-11-29. Estimated completion is 2026-12-31.
What conditions does trial NCT05877729 study?
This clinical trial studies the following conditions: Substance Use, HIV/AIDS, Mental Health Issue, Young Adult, Mobile Health.
What interventions are being tested in trial NCT05877729?
The interventions under investigation include: Standard of Care (OTHER), Video-counseling+app (BEHAVIORAL).
Who is sponsoring clinical trial NCT05877729?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05877729 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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