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ClinicalTrials.gov 8 recruiting now early-phase tilt small index

Liposarcoma: early-phase trial registry

8 of 14 indexed Liposarcoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,230 of 28,707 conditions by registered trial count.

14 US clinical trials · 8 currently recruiting · #1,230 of 28,707 conditions by registered trial count

Liposarcoma: 14 US clinical trials tracked, 8 recruiting.

Liposarcoma is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is Baylor College of Medicine, running 4 of these trials.

Enrollment posture brief

Registry condition liposarcoma

OPEN 8 | RECR 57% | LATE 1 | EARLY 13 | RANK #1230 | SPON 4

Nearest open-share peer: ACL (57% recruiting · 7 trials)

Liposarcoma (this)57%Acute Respiratory Failure35.7%Adherence, Medication35.7%Acromegaly28.6%Abscess7.1%
Open-enrollment share among volume-matched conditions near Liposarcoma

Liposarcoma lists 8 open slots (57% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Liposarcoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Liposarcoma is recruiting above its size-band peers.

    8 of 14 indexed trials (57.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Liposarcoma research.

    Baylor College of Medicine accounts for 4 of 14 trials (28.6%). 11 distinct sponsors appear on at least one study for this condition label.

  3. Most Liposarcoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 24 among the 14 trials that report a genuine target (sentinel values excluded). 10 of those (71.4%) plan for fewer than 100 participants.

  4. Liposarcoma research is mostly interventional.

    14 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 23Phase 31

Open and recent trials

14 total, page 1 of 1

RECRUITING Phase 3 250 participants

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

European Organisation for Research and Treatment of Cancer - EORTC

NCT04031677

RECRUITING Phase 1 139 participants

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

St. Jude Children's Research Hospital

NCT06239272

RECRUITING Phase 1 104 participants

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

Milton S. Hershey Medical Center

NCT06541262

RECRUITING Phase 1 54 participants

A Study of Mirdametinib in Combination With Palbociclib in People With Liposarcoma

Memorial Sloan Kettering Cancer Center

NCT06843967

RECRUITING Phase 1 24 participants

BTX-A51 in Patients With Liposarcoma or CIC-rearranged Sarcoma

Michael Wagner, MD

NCT06414434

RECRUITING Phase 1 24 participants

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Baylor College of Medicine

NCT04715191

RECRUITING Phase 1 21 participants

Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells

Baylor College of Medicine

NCT06198296

RECRUITING Phase 1 21 participants

Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells

Seattle Children's Hospital

NCT07148050

ACTIVE NOT RECRUITING Phase 2 362 participants

Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors

Pfizer

NCT04557449

ACTIVE NOT RECRUITING Phase 2 40 participants

Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery

National Cancer Institute (NCI)

NCT02923778

ACTIVE NOT RECRUITING Phase 1 15 participants

Eribulin and Radiation Therapy in Treating Patients With Retroperitoneal Liposarcoma That Can Be Removed by Surgery

OHSU Knight Cancer Institute

NCT03361436

ACTIVE NOT RECRUITING Phase 1 14 participants

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Baylor College of Medicine

NCT04377932

ACTIVE NOT RECRUITING Phase 1 12 participants

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors

Baylor College of Medicine

NCT05103631

COMPLETED Phase 2 20 participants

Bevacizumab and Radiation Therapy for Sarcomas

Massachusetts General Hospital

NCT00356031

Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 3
Phase 3 1

Named interventions

Most-linked intervention names on Liposarcoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Surgery Procedure
2 trials
Radiation Therapy Radiation
2 trials
Fulvestrant Combination
1 trials
Letrozole Combination
1 trials
AGAR T cells Genetic
1 trials
Talimogene Laherparepvec Biological
1 trials
CATCH T cells Genetic
1 trials
Eribulin Mesylate Drug
1 trials

US sites by state

Facility locations filed on Liposarcoma trials. A trial with sites in several states counts in each.

Texas 7 trials
Tennessee 4 trials
Massachusetts 4 trials
California 4 trials
Missouri 3 trials
Florida 3 trials
Arizona 3 trials
Virginia 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Liposarcoma page

14 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Liposarcoma condition card totals 14 registered trials; most-linked intervention Surgery; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.