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NCT06843967 · ClinicalTrials.gov registry record · Phase 1
A Study of Mirdametinib in Combination With Palbociclib in People With Liposarcoma
A Phase 1 study of Liposarcoma and Unresectable Dedifferentiated Liposarcoma, sponsored by Memorial Sloan Kettering Cancer Center.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 54
- Enrollment target
- 7
- Study locations
NCT06843967 is a Phase 1 study of Liposarcoma and Unresectable Dedifferentiated Liposarcoma that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 54 participants, below the 80-participant average among 13 other Liposarcoma trials with a reported enrollment target (32% lower). The trial reports 7 study locations across 2 states.
The verdict
NCT06843967, a Phase 1 study of Liposarcoma and Unresectable Dedifferentiated Liposarcoma, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 54 participants
- Enrollment target
- 7
- Study locations
Study Summary
The purpose of this study is to find out whether mirdametinib in combination with palbociclib is an effective and safe treatment for people with metastatic, recurrent, and unresectable liposarcoma. This study will test different doses of mirdametinib in combination with a fixed dose of palbociclib to find the best safe dose for further testing.
Conditions Studied
Interventions
- DRUG Palbociclib
- DRUG Mirdametinib
Study Locations (7)
New York
- Memorial Sloan Kettering Cancer Center Suffolk- Commack (Limited Protocol Activities) - Commack
- Memorial Sloan Kettering Westchester (Limited Protocol Activities) - Harrison
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) - New York
- Memorial Sloan Kettering Nassau (Limited Protocol Activities) - Uniondale
New Jersey
- Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities) - Basking Ridge
- Memorial Sloan Kettering Monmouth (Limited Protocol Activities) - Middletown
- Memorial Sloan Kettering Bergen (Limited Protocol Activities) - Montvale
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2025-02-19 |
| Est. Completion | 2028-08-19 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06843967
The ClinicalTrials.gov registry entry for NCT06843967 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 54 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 80-participant average among 13 other Liposarcoma trials with a reported enrollment target (32% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.
The record links to 9 conditions, with Liposarcoma appearing as the primary indexed condition, and to 2 interventions - of which Palbociclib is the first listed.
NCT06843967 reports 7 study locations spanning 2 distinct geographic areas - top geographies include New York, New Jersey.
Frequently Asked Questions
What is clinical trial NCT06843967 about?
NCT06843967 is a clinical study titled "A Study of Mirdametinib in Combination With Palbociclib in People With Liposarcoma". The purpose of this study is to find out whether mirdametinib in combination with palbociclib is an effective and safe treatment for people with metastatic, recurrent, and unresectable liposarcoma. This study will test different doses of mirdametinib in combination with a fixed dose of palbociclib t...
What is the current status of trial NCT06843967?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 54 participants. The study started on 2025-02-19. Estimated completion is 2028-08-19.
What conditions does trial NCT06843967 study?
This clinical trial studies the following conditions: Liposarcoma, Unresectable Dedifferentiated Liposarcoma, Dedifferentiated Liposarcoma, Unresectable Liposarcoma, Myxoid Liposarcoma.
What interventions are being tested in trial NCT06843967?
The interventions under investigation include: Palbociclib (DRUG), Mirdametinib (DRUG).
Who is sponsoring clinical trial NCT06843967?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06843967 being conducted?
This trial has 7 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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