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ClinicalTrials.gov 3 recruiting now official registry

Influenza, Human clinical trials

3 of 19 indexed Influenza, Human trials are currently recruiting.

19 US clinical trials · 3 currently recruiting

Influenza, Human is the subject of 19 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 8 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is GlaxoSmithKline, running 5 of these trials.

The research picture

Influenza, Human has 19 registered US clinical trials, 3 of them open to new participants right now, about 16% of the total.

3
recruiting participants now
16%
of trials open to enrollment
8
in Phase 3–4 (later-stage)
5
top sponsor: GlaxoSmithKline
Phase 13Phase 23Phase 35Phase 43

Active & Recent Trials

19 total, page 1 of 1

RECRUITING Phase 2 960 participants

A Study to Evaluate the Immune Response and Safety of an Influenza Vaccine in Adults 18 Years of Age and Above

GlaxoSmithKline

NCT07204964

RECRUITING Phase 4 700 participants

Characterization of Humoral and Cellular Immune Responses Elicited by Influenza Vaccination in Healthy Adults

University of Pennsylvania

NCT05108818

RECRUITING 50 participants

Flu Infection at UPHS

University of Pennsylvania

NCT06807840

ACTIVE NOT RECRUITING Phase 3 35,800 participants

A Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of an Adjuvanted Influenza Vaccine Compared to a Non-adjuvanted Influenza Vaccine in Adults ≥65 Years of Age

Seqirus

NCT06087640

ACTIVE NOT RECRUITING Phase 2 776 participants

A Study to Assess the Immune Response and Safety of a Vaccine Against Influenza in Adults 18 Years of Age and Older

GlaxoSmithKline

NCT07121192

COMPLETED NA 228,000 participants

Mail Outreach To Increase Vaccination Acceptance Through Engagement

Brigham and Women's Hospital

NCT02243774

COMPLETED 18,157 participants

Wearable Assisted Viral Evidence (WAVE) Study A Decentralized, Prospective Study Exploring the Relationship Between Passively-collected Data From Wearable Activity Devices and Respiratory Viral Infections

Evidation Health

NCT06207929

COMPLETED Phase 3 2,250 participants

A Study to Evaluate the Immunogenicity and Safety of Seqirus Quadrivalent Influenza Vaccine (QIV) in a Pediatric Population 6 Months Through 59 Months of Age.

Seqirus

NCT02914275

COMPLETED Phase 3 2,044 participants

A Clinical Study to Evaluate the Immunogenicity and Safety of an Adjuvanted Quadrivalent Influenza Vaccine Compared With a Licensed Quadrivalent Vaccine in Adults 50 to 64 Years of Age

Seqirus

NCT05044195

COMPLETED Phase 2 1,019 participants

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of Combined Modified RNA Vaccine Candidates Against COVID-19 and Influenza

BioNTech SE

NCT05596734

COMPLETED Phase 3 626 participants

A Study of Intravenous Zanamivir Versus Oral Oseltamivir in Adults and Adolescents Hospitalized With Influenza

GlaxoSmithKline

NCT01231620

COMPLETED Phase 4 465 participants

Immunologic Response to FluMist vs. Flucelvax

Richard Zimmerman MD

NCT03982069

COMPLETED Phase 1 440 participants

A Study To Learn About The Study Vaccine (Called Self-Amplifying Ribonucleic Acid (RNA)) For The Prevention of Influenza

Pfizer

NCT05227001

COMPLETED Phase 4 402 participants

A Study to Evaluate the Safety and Tolerability of Trivalent Influenza Virus Vaccine in Children Aged 5 Years to < 9 Years

Seqirus

NCT02212106

COMPLETED Phase 3 228 participants

A Study of Oseltamivir (Tamiflu) for Treatment of Influenza in Immunocompromised Participants.

Hoffmann-La Roche

NCT00545532

COMPLETED Phase 1 40 participants

A Study to Evaluate the Effect of Intravenous Zanamivir on Cardiac Conduction in Healthy Volunteers

GlaxoSmithKline

NCT01353729

COMPLETED NA 29 participants

Resistance Exercise to Improve Flu Vaccine for Older Adults

University of Houston

NCT03736759

COMPLETED Phase 1 28 participants

A Study to Evaluate the Bioequivalence of Over-encapsulated Oseltamivir Capsules to Marketed Oseltamivir Capsules in Healthy Volunteers

GlaxoSmithKline

NCT01258530

COMPLETED 10 participants

Kinetics of the Immune Response to Inactivated Influenza Vaccine in Healthy Adults

Vanderbilt University Medical Center

NCT03743688

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 3
Phase 3 5
Phase 4 3

Top Sponsors

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Influenza, Human Trial Landscape

19 indexed Influenza, Human studies · 3 recruiting (16%).

Phase mix: 8 late (III/IV) vs 6 early (I/II).

Top sponsor: GlaxoSmithKline (5 trials), 9 others listed. 19 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Influenza, Human?

PlainTrial tracks 19 US clinical trials for Influenza, Human, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Influenza, Human?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.