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2026 data Public-data reference. official source

Bacterial Infections

Open-data reference.

19 US clinical trials · 3 currently recruiting

Active & Recent Trials

RECRUITING Phase 3 386 participants

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

Grifols Therapeutics

NCT05645107

RECRUITING Phase 1 40 participants

A Study to Investigate Safety and Pharmacokinetics of Intravenous Cefiderocol/Xeruborbactam in Participants With Renal Impairment

Qpex Biopharma

NCT07104162

RECRUITING Phase 1 20 participants

[18F]Fluoropropyl-Trimethoprim ([18F]F-TMP) PET/CT Imaging to Evaluate Biodistribution and Kinetics in Human Subjects

University of Pennsylvania

NCT04263792

ACTIVE NOT RECRUITING Phase 1 39 participants

Dose-finding, Pharmacokinetics, and Safety of VABOMERE in Pediatric Subjects With Bacterial Infections

Rempex (a wholly owned subsidiary of Melinta Therapeutics, LLC)

NCT02687906

COMPLETED Phase 3 680 participants

Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections

Forest Laboratories

NCT00423657

COMPLETED Phase 3 598 participants

Efficacy and Safety of Intravenous to Oral 6-Day Tedizolid Phosphate vs. Intravenous to Oral 10-Day Linezolid in Patients With Acute Bacterial Skin and Skin Structure Infection (ABSSSI)

Bayer

NCT02066402

COMPLETED Phase 1 123 participants

Study of the Safety and Pharmacokinetics of KSP-1007 Alone and Coadministered With Meropenem in Healthy Subjects

Sumitovant Biopharma

NCT05226923

COMPLETED Phase 1 88 participants

Study to Evaluate Safety, Tolerability, and Pharmacokinetics of XNW4107 Alone or in Combination With Imipenem/Cilastatin

Evopoint Biosciences

NCT04482569

COMPLETED 83 participants

OR PathTrac (Tracking Intra-operative Bacterial Transmission)

Sundara Reddy

NCT03605498

COMPLETED Phase 1 82 participants

P1 Single and Multiple Ascending Dose (SAD/MAD) Study of IV QPX7728 Alone and Combined With QPX2014 in NHV

Qpex Biopharma

NCT04380207

COMPLETED Phase 1 62 participants

A Pilot of Pediatric/Adult Study of Gene Expression Profiling and Clinical Characterization of Phototoxicity

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT00353158

COMPLETED Phase 1 40 participants

A Phase 1 TP-271 Oral PK Multiple Ascending Dose Study

Tetraphase Pharmaceuticals

NCT03450187

COMPLETED 39 participants

Blood Volume Assessment in COVID-19 and Bacterial Sepsis

NYU Langone Health

NCT04517695

COMPLETED Phase 1 36 participants

Safety, Tolerability, Pharmacokinetics of Intravenous RPX2003 (Biapenem) in Healthy Adult Subjects

Rempex Pharmaceuticals (a wholly owned subsidiary of The Medicines Company)

NCT01702649

COMPLETED Phase 1 32 participants

PK & Safety Study of Xeruborbactam Oral Prodrug Combined With Ceftibuten in Participants With Renal Impairment

Qpex Biopharma

NCT06157242

COMPLETED Phase 1 22 participants

Safety and Pharmacokinetics of Clindamycin in Pediatric Subjects With BMI ≥ 85th Percentile

Phillip Brian Smith

NCT01744730

COMPLETED Phase 1 20 participants

Evaluation of Atuna Racemosa Toxicity

Mayo Clinic

NCT00318344

COMPLETED Phase 1 12 participants

A Study of Azithromycin in HIV-Infected Patients

Pfizer

NCT00002344

COMPLETED Phase 1

Phase I Study of the Clinical Pharmacology of Azithromycin in Buffy Coat of HIV-Infected Subjects.

Pfizer

NCT00002139

Phase Distribution

PhaseTrial count
Early Phase 1 14
Phase 3 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Bacterial Infections Trial Landscape

ClinicalTrials.gov lists 19 US studies indexed under Bacterial Infections, and 3 of those are currently open to recruitment — roughly 16% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Bacterial Infections shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 14 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Bacterial Infections is led by Qpex Biopharma with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 19 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Bacterial Infections?

PlainTrial tracks 19 US clinical trials for Bacterial Infections, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Bacterial Infections?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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